Detecting spam e-mails using stop word TF-IDF and stemming algorithm with Naïve Bayes classifier on the multicore GPU

A spam filter is a program which is used to identify unwanted emails and prevents those messages from getting into a user's mail. The study was focused on how the algorithms can be applied on a number of e-mails consisting of both ham and spam e-mails. First, the working principle and steps which are followed for implementation of stop words, TF-IDF and stemming algorithm on NVIDIA’s Tesla P100 GPU are discussed and to verify the findings by executing of Naïve Bayes algorithm. After complete training and testing of the spam e-mails dataset taken from Kaggle by using the proposed method, we got a high training accuracy of 99.67% and got a testing accuracy of about 99.03% on the multicore GPU that boosted the speed of execution of training time period and testing time period which is improved of training and testing accuracy around 0.22% and 0.18% respectively when compared to that after applying only Naïve Bayes i.e. conventional method to the same dataset where we found training and testing accuracy to be 99.45% and 98.85% respectively. Also, we found that training time taken on GPU is 1.361 seconds which was about 1.49X faster than that taken on CPU which is 2.029 seconds. And the testing time taken on GPU is 1.978 seconds which was about 1.15X faster than that taken on CPU which is 2.280 seconds

Transpedicular screw fixation for the treatment of thoracolumbar spine fracture

One of the most popular procedures for treating the unstable thoracolumbar fracture is the short segment pedicle screw fixation. Due to lack of adequate neurological improvement, progressive kyphosis and hardware failure, the efficacy of different methods remain debatable. One hundred patients of thoracolumbar burst fractures were managed from January 2010 to December 2014 by  transforaminal thoracolumbar interbody fusion and short-segment pedicle screw stabilization. Each patient was followed-up for a minimum of 2 years. Bony fusion was done in each patient in between two vertebra along with transpedicular fixation. Follow-up radiological images showed good reduction and the fusion of the vertebral body was good. Excellent neurological improvement of the Frankel grade C and D was seen in 81 patients. Eight patients had  grade B, improvement which was not satisfactory. Fifteen patients with no paraplegia/hemiplegia on admission remained neurologically intact. For the management of thoracolumbar burst fractures short segment posterior transpedicular fixation with bone graft is very economic and safe procedure with good neurological improvement

Transpedicular screw fixation for the treatment of thoracolumbar spine fracture

One of the most popular procedures for treating the unstable thoracolumbar fracture is the short segment pedicle screw fixation. Due to lack of adequate neurological improvement, progressive kyphosis and hardware failure, the efficacy of different methods remain debatable. One hundred patients of thoracolumbar burst fractures were managed from January 2010 to December 2014 by  transforaminal thoracolumbar interbody fusion and short-segment pedicle screw stabilization. Each patient was followed-up for a minimum of 2 years. Bony fusion was done in each patient in between two vertebra along with transpedicular fixation. Follow-up radiological images showed good reduction and the fusion of the vertebral body was good. Excellent neurological improvement of the Frankel grade C and D was seen in 81 patients. Eight patients had  grade B, improvement which was not satisfactory. Fifteen patients with no paraplegia/hemiplegia on admission remained neurologically intact. For the management of thoracolumbar burst fractures short segment posterior transpedicular fixation with bone graft is very economic and safe procedure with good neurological improvement

Correlation between Glasgow coma scale on admission and clinical outcome of patients with unilateral chronic subdural hematoma after surgery

This study was undertaken to determine the influence of Glasgow coma scale (GCS) on admission on clinical outcome of patients with unilateral chronic subdural hematoma after surgery. A cross- sectional study was conducted on 33 consecutive patients, among them 28 were male, 5 were female with GCS 6 to 15. 19 patients out of 22 who had GCS 14-15 had favorable GOS at 24 hours as compared to 2 out of 7 in GCS 9-13 group and none in GCS ?8 group. All patients (22 out of 22) had favorable GOS at the time of discharge in GCS 14-15 group while 8 out of 9 had favorable GOS in GCS 9-14 group and 1 out of 2 patients had favorable GOS in GCS ?8 group. Chi square test showed significant difference in outcome between 14-15, 9-13 and ?8 GCS groups (p values 0.001, 0.015, 0.013 respectively). In conclusion, clinical outcome of patients with unilateral chronic subdural hematoma depends on Glasgow coma scale on admission.

Pre-clinical study on hypo-testicular activity of hydro-ethanol (60:40) extract of Areca catechu (L.) in albino rat: Dose-dependent response

The study focused to assess the dose-dependent hypo-testicular activity of hydro-ethanol seed extract of Areca catechu (10, 20 and 40 mg/ 100 g body weight) in albino rats. For this purpose, body weight, reproductive organo-somatic indices, as well as motility, count, hypo-osmotic swelling and acrosomal cap status of sperm along with the quantity of testicular androgenic key enzyme activities, serum testosterone, oxidative stress sensors, seminal vesicular fructose (SVF), apoptosis linked gene expression study and histology of testicular tissue for spermatokinetics were covered here. All the said doses revealed a significant (p<0.05) downward deviation in spermiological profile, serum testosterone, SVF levels, activities of testicular ∆5,3β and 17β-HSD, seminiferous tubular diameter compared to the vehicle-treated control (VTC). In contrast to the VTC, activities of superoxide dismutase and peroxidase were decreased along with elevation in the levels of thio-barbituric acid reactive substances significantly (p<0.05) in testis and sperm pellet of extract-treated groups. Testicular pro-apoptotic Bax gene expression was elevated and anti-apoptotic Bcl-2 gene expression was diminished significantly (p<0.05) after extract treatment compared to the VTC. Non-significant changes (p>0.05) were noted in hepatic acid and alkaline phosphatase activities which focused the non-toxic characteristics of said extract in general. This study interpreted that, 40 mg showed drastic hypo-testicular efficacy cum necrotic changes compared to other doses though the therapeutic dose that cross the borderline of fertile sensors from spermiological indicators is 20 mg dose. Liquid chromatography-mass spectrometry analysis of the said extract showed that ten phyto-molecules belong to flavonoid, alkaloid and isoflavone groups mainly

Clinical outcomes and recurrences after homologous autoimplantation therapy for warts: A prospective study

Background: Warts are mucocutaneous infections caused by human papillomavirus (HPV). Of the various modalities of treatment currently available, no single modality is uniformly efficacious and recurrences are common. Homologous autoimplantation is a minimally invasive procedure, which treats warts by stimulating a specific immune response against HPV. Aim: The aim of the study was to evaluate the clinical outcomes and recurrences after a single sitting of homologous autoimplantation therapy for multiple nonvenereal warts. Materials and Methods: Single homologous autoimplantation of wart tissue was done in 75 patients of multiple facial, palmoplantar, or common warts, reporting to a tertiary care dermatology center. They were assessed at 3 months for the outcome of the procedure, and those with complete clearance were followed up for 1 year for any recurrences. Results: Complete clearance was observed in 30 (40%) of the cases and 10 (13.3%) cases showed moderate clearance. In 13 (17.3%) cases, there was mild clearance, whereas 22 (29.3%) patients did not show any response to treatment. Patients with facial warts showed good therapeutic response with complete clearance seen in 62.5%, compared to plantar warts, where complete clearance was achieved only in 16%. At the end of the study period, recurrence was seen in only 1 (3.33%) patient in the complete clearance group. Conclusion: Autoimplantation therapy as a one time minimally invasive procedure has moderate efficacy in treating multiple warts with the best outcome being for facial warts. The virus-specific immunity generated in the process reduces the chances of recurrences

Transpedicular screw fixation for the treatment of thoracolumbar spine fracture

One of the most popular procedures for treating the unstable thoracolumbar fracture is the short segment pedicle screw fixation. Due to lack of adequate neurological improvement, progressive kyphosis and hardware failure, the efficacy of different methods remain debatable. One hundred patients of thoracolumbar burst fractures were managed from January 2010 to December 2014 by  transforaminal thoracolumbar interbody fusion and short-segment pedicle screw stabilization. Each patient was followed-up for a minimum of 2 years. Bony fusion was done in each patient in between two vertebra along with transpedicular fixation. Follow-up radiological images showed good reduction and the fusion of the vertebral body was good. Excellent neurological improvement of the Frankel grade C and D was seen in 81 patients. Eight patients had  grade B, improvement which was not satisfactory. Fifteen patients with no paraplegia/hemiplegia on admission remained neurologically intact. For the management of thoracolumbar burst fractures short segment posterior transpedicular fixation with bone graft is very economic and safe procedure with good neurological improvement

Resolution of Papilledema Following Ventriculoperitoneal Shunt or Endoscopic Third Ventriculostomy for Obstructive Hydrocephalus: A Pilot Study

Background and Objectives: Ventriculoperitoneal Shunt (VPS) and Endoscopic Third Ventriculostomy (ETV) are both gold standard procedures to reduce intracranial pressure (ICP) in patients with obstructive hydrocephalus, which often results in papilledema. This comparative study was carried out at the Department of Neurosurgery of Dhaka Medical College and Hospital to compare the efficacy of VPS and ETV in the resolution of papilledema in 18 patients with obstructive hydrocephalus. Materials and Methods: The success of CSF diversion was evaluated by a decrease in retinal nerve fiber layer (RNFL) thickness by optical coherence tomography (OCT) and modified Frisen grading of papilledema at the same time. The statistical analyses were carried out by using paired sample t test and the Spearman’s correlation coefficient test. The level of significance (p value) was set at Results: After 7 days, both VPS and ETV were able to reduce RNFL thickness of both eyes with a p value = 0.016 (right eye) and 0.003 (left eye) in group A (VPS) and with a p value p value > 0.05. Further, the inter-group comparison between VPS and ETV showed no difference in decreasing RNFL thickness and modified Frisen grading (p value = 0.56). Conclusion: VPS and ETV procedures both appear very efficient in treating obstructive hydrocephalus, which in turn reduces papilledema in these patients. This paper is preliminary and requires further work