229 research outputs found

    Sequences of Fuzzy Soft Multi Points

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    In this paper we introduce a new sequence of fuzzy soft multi points in fuzzy soft multi topological space. The concepts of subsequence and convergence sequence of fuzzy soft multi points are proposed. The notion of cluster fuzzy soft multi points of sequences are also introduced. Some basic properties regarding the above concepts are explored

    Assessment of Damage in Prismatic Beams Using Modal Parameters

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    In this study, the modal parameters of un-cracked and cracked plain cement concrete prismatic beams have been studied. A crack in a beam element introduces considerable local flexibility, which has been expressed by local flexibility matrix, the dimension of which depends upon the numbers of degree of freedom considered. An approach based on linear fracture mechanics theory has been used to find flexibility matrix for the cracked element. The FEM program has been developed for eigen-value problems to determine the modal parameters of the cracked beams. Numerical studies are performed by considering simply supported beam with single and multiple cracks at different locations with different crack depths. The changes in displacement mode shapes are not localized in the region of damage and hence, they do not give indication of the location of damage very precisely. With curvature mode shape, the damage location can be attained in a very efficient manner. The absolute changes in the curvature mode shapes of the damaged and intact structure are localized in the region of damage and hence can be used to detect the damage in a structure. Curvature damage factors are also calculated with the help of curvature mode shapes for the number of modes considered to detect the damage in a structure

    A study of Ka-Band Signal Attenuation at Umiam, Meghalaya with ISRO’s GSAT-14 Satellite

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    A study at NE-SAC, Umiam of Rain Attenuation to Ka-Band signals has been made with ISRO’s GSAT-14 Satellite carrying two Ka-Band beacons at 20.2 Ghz and 30.5 Ghz and with the help of instruments like High Gain receiving antennas; Humidity Profiler Radiometer, Tipping Bucket Rain Gauge , GPS antenna etc.. The study has been a joint collaboration of ISRO and CNES/ONERA, the French Aerospace Lab. The study comprises simultaneous signal attenuation and rainfall recording of a time period ranging from Pre-Monsoon to Post –Monsoon season at Umiam, from March to October for the year 2016

    Chemistry of ruthenium with some dioxime ligands. Syntheses, structures and reactivities

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    Reaction of two dioxime ligands, viz. dimethylglyoxime (H2dmg) and diphenylglyoxime (H2dpg), (abbreviated in general as H2L, where H stands for the oxime protons) with [Ru(PPh3)3Cl2] in 1¦1 mole ratio affords complexes of type [Ru(PPh3)2(H2L)Cl2]. Structure of the [Ru(PPh3)2(H2dpg)Cl2] complex has been solved by X-ray crystallography. The coordination sphere around ruthenium is N2P2Cl2 with the two PPh3 ligands in trans and the two chlorides in cis positions. Reaction of the dioxime ligands with [Ru(PPh3)3Cl2] in 2¦1 mole ratio in the presence of a base affords complexes of type [Ru(PPh3)2(HL)2]. Structure of the [Ru(PPh3)2(Hdmg)2] complex has been solved by X-ray crystallography. The coordination sphere around ruthenium is N4P2 with the two PPh3 ligands in trans positions. Reaction of the [Ru(PPh3)2(H2dpg)Cl2] complex with a group of bidentate acidic ligands, viz. picolinic acid (Hpic), quinolin-8-ol (Hq) and 1-nitroso-2-naphthol (Hnn), (abbreviated in general as HL′, where H stands for the acidic proton) in the presence of a base affords complexes of type [Ru(PPh3)2(H2dpg)(L′)]+ isolated as perchlorate salts. All the complexes are diamagnetic (low-spin d6, S=0) and in dichloromethane solution show several intense MLCT transitions in the visible region. Cyclic voltammetry on all the complexes shows a reversible ruthenium(II)-ruthenium(III) oxidation within 0.36-0.98 V versus SCE followed by a quasi-reversible ruthenium(III)-ruthenium(IV) oxidation within 0.94-1.60 V versus SCE

    Modelling temporal and spatial features of collaboration network

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    The collaboration network is an example of a social network which has both non-trivial temporal and spatial dependence. Based on the observations of collaborations in Physical Review Letters, a model of collaboration network is proposed which correctly reproduces the time evolution of the link length distributions, clustering coefficients, degree distributions and assortative property of real data to a large extent.Comment: 8 pages, 10 figures; follow up work on arXiv.org/physics/0511181; accepted for publication in IJMP

    Vasculogenic Mimicry: Role of melanoma differentiation associated gene-9/syntenin

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    Malignant melanoma (MM) is the most aggressive skin cancer and the most frequent skin disorder in Caucasians. MM is associated with aggressive and progressive disease states, leading to major cancer-related morbidity and mortality. Recent investigations identify a new non-angiogenesis-dependent pathway vasculogenic mimicry (VM), which is considered a cancer hallmark that can independently facilitate tumor neovascularization by the formation of fluid-conducting and vascular endothelial cells. MM cells undergoing VM can dedifferentiate into numerous cellular phenotypes and acquire endothelial-like features, resulting in the formation of the de novo matrix-rich vascular-like network, such as plasma and red blood cells. The co-generation of endothelial cells, channels, laminar structures, and heparin sulfate proteoglycans are the main pathophysiological characteristics of VM in human melanoma patients. In highly aggressive melanoma cells downregulation of vascular endothelial cadherin and upregulation of ECM components promote the perfusion of the VM pathway. We investigated whether mda-9/syntenin, a pro-metastatic gene, affects VM in MM. The expression of mda-9/syntenin was modulated using gain-of-function and loss-of-function strategies to determine its potential role in VM. Downregulation of mda-9/syntenin in aggressive melanoma cells decreases VM, while over expressing mda-9/syntenin in immortalized melanoma cells increases VM. These findings shed light on a novel role and molecular mechanism of action of mda-9/syntenin in VM, which may contribute significantly to the metastatic phenotype of these aggressive cancers.https://scholarscompass.vcu.edu/gradposters/1137/thumbnail.jp
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