KARIN AĞRISININ NADİR BİR NEDENİ: APENDİKS MUKOSEL OLGU SUNUMU

Apendiksin mukoseli, apendiks lümeninin anormal müsinöz sekresyonu sebebiyle dilatasyonu ile karakterize nadir görülen klinik bir durumdur. İnflamatuar bir duruma veya tümör kaynaklı olabilir. Mukosel, mukozal hiperplazi, müsinöz kistadenom veya müsinöz kistadenokarsinom sonucunda oluşabilir. Apendiks müsinöz kistadenomu en sık görülen şekli olup çok farklı klinik durumlarla kendini belli eder. Apendektomi spesimenlerinin %0.2?0.3’ünde saptanır. Preoperatif tanı konması zordur ve sıklıkla laparotomide saptanır. Rüptür riski, klinik olarak cerrahları zorlamaktadır. Cerrahi planlanmasında tam bir konsensus olmamakla birlikte genellikle apendektomi ya da sağ hemikolektomi ameliyatları uygulanır. Bu yazımızda plastron apendisit tanısıyla takip edilip sağ alt kadran ağrısı ve kitle saptanan apendiks mukosel olgusunu literatür eşliğinde tartıştık.Appendiceal mucocele is a rare clinical condition characterized by dilatation of the appendix lumen due to abnormal mucin secretion. It may be due to inflammatory conditions or neoplastic lesions. Mucocele may occur as a result of mucosal hyperplasia, mucinous cystadenoma or mucinous cystadenocarcinoma histopathologically. Mucinous cystadenoma is the most common form and it manifests itself as many different clinical pictures. It is detected in 0.2?0.3%of appendectomy specimens. As preoperative diagnosis is often difficult, it is generally detected during laparotomy. Appendiceal mucocele is a clinical challenge for surgeons due to its risks of perforation and dissemination. Although there is no consensus for type of surgical treatment, appendectomy or right hemicolectomy are usually prefered. Herein, we present an appendiceal mucocele cystadenoma case with right lower quadrant pain and palpable mass who was followed up with the pre-diagnosis of plastron appendicitis in the context of the literature

A Rare Cause of Abdominal Pain: A Case of Appendiceal Mucocele

Apendiksin mukoseli, apendiks lümeninin anormal müsinöz sekresyonu sebebiyle dilatasyonu ile karakterize nadir görülen klinik bir durumdur. İnflamatuar bir duruma veya tümör kaynaklı olabilir. Mukosel, mukozal hiperplazi, müsinöz kistadenom veya müsinöz kistadenokarsinom sonucunda oluşabilir. Apendiks müsinöz kistadenomu en sık görülen şekli olup çok farklı klinik durumlarla kendini belli eder. Apendektomi spesimenlerinin %0.2?0.3’ünde saptanır. Preoperatif tanı konması zordur ve sıklıkla laparotomide saptanır. Rüptür riski, klinik olarak cerrahları zorlamaktadır. Cerrahi planlanmasında tam bir konsensus olmamakla birlikte genellikle apendektomi ya da sağ hemikolektomi ameliyatları uygulanır. Bu yazımızda plastron apendisit tanısıyla takip edilip sağ alt kadran ağrısı ve kitle saptanan apendiks mukosel olgusunu literatür eşliğinde tartıştık.Appendiceal mucocele is a rare clinical condition characterized by dilatation of the appendix lumen due to abnormal mucin secretion. It may be due to inflammatory conditions or neoplastic lesions. Mucocele may occur as a result of mucosal hyperplasia, mucinous cystadenoma or mucinous cystadenocarcinoma histopathologically. Mucinous cystadenoma is the most common form and it manifests itself as many different clinical pictures. It is detected in 0.2?0.3%of appendectomy specimens. As preoperative diagnosis is often difficult, it is generally detected during laparotomy. Appendiceal mucocele is a clinical challenge for surgeons due to its risks of perforation and dissemination. Although there is no consensus for type of surgical treatment, appendectomy or right hemicolectomy are usually prefered. Herein, we present an appendiceal mucocele cystadenoma case with right lower quadrant pain and palpable mass who was followed up with the pre-diagnosis of plastron appendicitis in the context of the literature

Healing of Ischemic Colon Anastomosis in Rats Could Be Provided by Administering Dexpanthenol or Coenzyme Q10

Background: In this study, the effectiveness of dexpanthenol and coenzyme Q10 (CoQ10) on the healing of ischemic colon anastomosis was investigated. Methods: Forty eight male Wistar Albino rats were divided into four equal groups (Sham-S, Sham-I, DXP, Q10). Following full layer colon resection, single layer colon anastomosis, without creating ischemia, was performed on the Sham-S group. The same experimental model was performed on remaining groups after ischemia was created. Intraperitoneal dexpanthenol and CoQ10 was administered to the DXP and Q10 groups once a day for three days. Ten days later, all colon anastomoses were investigated histopathologically and biochemically, as well as their burst pressure values, in all sacrificed rats. Results: The highest burst pressure value was observed in the Sham-S group, decreasing from high to low in the DXP, Q10, and Sham-I groups, respectively (p = 0.008). Furthermore, tissue hydroxyproline (p = 0.001) level values were significantly different among the groups. Additionally, histopathological analysis revealed a significant difference among groups regarding reepithelization (p = 0.027) and polymorphonuclear leukocyte density (p = 0.022). Conclusions: This preliminary study has shown that ischemia-reperfusion injury may impair the healing of colon anastomosis and it has been concluded that dexpanthenol and CoQ10 may have positive effects on the healing of ischemic colon anastomosis in rat, although re-epithelization may be adversely affected using CoQ10