Monoclinic form of (cyanato-κN){2,2′-[ethane-1,2-diylbis(nitrilo­methyl­idyne)]diphenolato-κ4 O,N,N′,O′}manganese(III)

The title compound, [Mn(C16H14N2O2)(NCO)], is a monoclinic polymorph of the previously published ortho­rhom­bic form [Lu et al. (2006 ▶). Inorg. Chem. 45, 3538–3548]. The MnIII ion is chelated by a tetra­dentate Schiff base ligand and coordinated by the N atom of a cyanate ligand in a distorted square-pyramidal arrangement. In the crystal, there are short inter­molecular Mn⋯Ophenolate distances of 2.752 (3) Å between pairs of inversion-related mol­ecules

3,3′-(m-Phenyl­enedi­oxy)diphthalonitrile

In the title compound, C22H10N4O2, the dihedral angles between the mean planes of the central benzene ring and the pendant rings are 79.20 (6) and 80.29 (6)°. The dihedral angle between the pendant rings is 10.27 (7)°

8,10-Diiodo-2,6-dioxo-4λ3-ioda-3,5-dioxatricyclo­[5.3.1.04,11]undeca-1(11),7,9-triene-9-carb­oxy­lic acid

In the title compound, C9HI3O6·2H2O, the mol­ecule is located on a twofold axis that gives rise to disorder of the carboxyl group. This disorder is correlated with the disorder of one of the H atoms of the water mol­ecule. The carboxyl group is twisted relative to the attached benzene ring by 75.1 (4)°. The intra­molecular I⋯O distance is 2.112 (6) Å. Mol­ecules are linked via O—H⋯O hydrogen bonding, C—I⋯O halogen bonding, with I⋯O distances in the range 3.156 (5)–3.274 (6) Å, and dipolar C=O⋯C=O inter­actions between the carboxyl and carboxyl­ate groups, with an O⋯C distance of 2.944 (10) Å

Preparation, structural and magnetic characterization of trinuclear and one-dimensional cyanide-bridged Co(III)-Cu(II) complexes

341-345By employing two trans-dicyanocobolt(III) building blocks K[Co(bpb)(CN)2] (bpb2- = 1,2-bis(pyridine-2-carboxamido)benzenate), K[Co(bpmb)(CN)2] (bpmb2- = 1,2-bis(pyridine-2-carboxamido)-4-methyl-benzenate) and one 14-membered macrocycle Cu(II) compound as assembling segment, two cyanide-bridged CoIII-CuII complexes {{[Cu(cyclam)][Co(bpb)(CN)2]}ClO4}n·nCH3OH·nH2O (1) and {[Cu(cyclam)][Co(bpmb)(CN)2]2}·4H2O (2) (cyclam = 1,4,8,11-tetraazacyclotetradecane) have been successfully prepared and characterized by elemental analysis, IR spectroscopy and X-ray structure determination. Single X-ray diffraction analysis shows that complex 1 can be structurally characterized as one-dimensional cationic single chain consisting of alternating units of [Cu(cyclam)]2+ and [Co(bpb)(CN)2]- with free ClO4- as balanced anion, while complex 2 presents cyanide-bridged neutral trinuclear bimetallic structure containing Co2Cu core, giving clear information that the substitute group on the cyanide precursor has obvious influence on the structure type of the target compound. Investigation over magnetic properties of complex 1 reveals the weak antiferromagnetic coupling between the neighboring Cu(II) ions through the diamagnetic cyanide building block

The Paramagnetic or Spin Crossover Iron(III) Complexes Based-on Pentadentate Schiff Base Ligand: Crystal Structure, and Magnetic Property Investigation

A series of bi- or mononuclear hexacoordinate iron(III) complexes, [Fe(L)][Fe(bpb)(CN)2]·CH3OH·0.5H2O (1), [Fe(L)][Co(bpb)(CN)2]·CH3OH (2) [(Fe (L))2(4,4’-bipy)](BPh4)2 (3), [Fe(L)(py)](BPh4) (4) and [Fe(L)(dmap)](BPh4) (5) (bpb = 1,2-bis(pyridine-2-carboxamido)benzenate, L = N,N’-bis(2-hydroxybenzyliden)-1,7-diamino-4-azaheptane, dmap = 4-dimethylaminopyridine), have been prepared with the pentadentate Schiff base iron(III) compound as assemble precursor and characterized by element analysis, IR and X-ray diffraction. Single crystal structural determination revealed the neutral cyanide-bridged binuclear entity for complexes 1 and 2 and the cationic di- or mononuclear structure for complexes 3–5 with the positive charge(s) balanced by BPh4– ion(s). The experimental study and theoretical simulation of the magnetic property discovered the ferromagnetic coupling between the Fe(III) ions bridged by cyanide group in complex 1 and the always high spin state of the Fe(III) ion coordinated to the Schiff base ligand in both complexes 1 and 2. The temperature dependent magnetic susceptibility investigation over complexes 3–5 showed the occurrence of the thermo-induced gradual complete spin crossover (SCO) property at about 115, 170 and 200 K, respectively

Spin Crossover in a Series of Non-Hofmann-Type Fe(II) Coordination Polymers Based on [Hg(SeCN)3]-; or [Hg(SeCN)4]2-; Building Blocks

This document is the Accepted Manuscript version of a Published Work that appeared in final form in Inorganic Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://pubs.acs.org/doi/10.1021/acs.inorgchem.1c00802.[EN] Self-assembly of [Hg(SeCN)(4)](2)-tetrahedral building blocks, iron(II) ions, and a series of bis-monodentate pyridyltype bridging ligands has afforded the new heterobimetallic Hg-II-Fe-II coordination polymers {Fe[Hg(SeCN)(3)](2)(4,4'-bipy)(2)}(n) (1), {Fe[Hg(SeCN)(4)](tvp)}(n) (2), {Fe[Hg(SeCN)(3)](2)(4,4'-azpy)(2)}(n) (3), {Fe[Hg(SeCN)(4)](4,4'-azpy)(MeOH)} n (4), {Fe[Hg(SeCN)(4)](3,3'- bipy)} n (5) and {Fe[Hg(SeCN)4](3,3'-azpy)}(n) (6) (4,4-bipy = 4,4'-bipyridine, tvp = trans-1,2-bis(4-pyridyl)ethylene, 4,4'-azpy = 4,4'-azobispyridine, 3,3-bipy = 3,3'bipyridine, 3,3'-azpy = 3,3'-azobispyridine). Single-crystal X-ray analyses show that compounds 1 and 3 display a two-dimensional robust sheet structure made up of infinite linear [(FeL)n]2n+ (L = 4,4'-bipy or 4,4'-azpy) chains linked by in situ formed {[Hg(L)(SeCN)(3)](2)}(2)-anionic dimeric bridges. Complexes 2 and 4-6 define three-dimensional networks with different topological structures, indicating, in combination with complexes 1 and 3, that the polarity, length, rigidity, and conformation of the bridging organic ligand play important roles in the structural nature of the products reported here. The magnetic properties of complexes 1 and 2 show the occurrence of temperature-and light-induced spin crossover (SCO) properties, while complexes 4-6 are in the high-spin state at all temperatures. The current results provide a new route for the design and synthesis of new SCO functional materials with non-Hofmann-type traditional structures.This work was supported by the Natural Science Foundation of China (21671121and 21773006), the Spanish Ministerio de Ciencia e Innovacion (MICINN) and FEDER funds (PID2019-106147GB-I00), and Unidad de Excelencia Maria de Maeztu (CEX2019-000919-M).Cao, T.; Valverde-Muñoz, FJ.; Duan, X.; Zhang, M.; Wang, P.; Xing, L.; Sun, F.... (2021). Spin Crossover in a Series of Non-Hofmann-Type Fe(II) Coordination Polymers Based on [Hg(SeCN)3]-; or [Hg(SeCN)4]2-; Building Blocks. Inorganic Chemistry. 60(15):11048-11057. https://doi.org/10.1021/acs.inorgchem.1c008021104811057601

Apelin-13 Administration Protects Against LPS-Induced Acute Lung Injury by Inhibiting NF-κB Pathway and NLRP3 Inflammasome Activation

Background/Aims: Acute lung injury (ALI) is induced by a variety of external and internal factors and leads to acute progressive respiratory failure. Previous studies have shown that apelin-13 can decrease the acute lung injury induced by LPS, but the specific mechanism is unclear. Therefore, a mouse lung injury model and a cell model were designed to explore the mechanism of how apelin-13 alleviates the acute lung injury caused by LPS. Methods: The effect of apelin-13 on LPS-induced structural damage was determined by H&E staining and by the wet/dry weight ratio. The related inflammatory factors in BALF were examined by ELISA. The apoptotic pathway and the NF-κB and NLRP3 inflammasome pathways were evaluated by using Western blotting and immunofluorescence staining. Results: LPS induced the structural damage and the production of inflammatory cytokines in the lung tissues of mice. These deleterious effects were attenuated by apelin-13 administration. The protective effects of apelin-13 were associated with decreased reactive oxygen species (ROS) formation and the inhibition of the activation of the NF-κB and NLRP3 inflammasome pathways in mice and in Raw264.7 cells. Conclusion: Taken together, these data suggest that apelin-13 administration ameliorates LPS-induced acute lung injury by suppressing ROS formation, as well as by inhibiting the NF-κB pathway and the activation of the NLRP3 inflammasome in the lungs

Bis(4-chloropyridine){2,2′-[ethane-1,2-diylbis(nitrilomethylidyne)]diphenolato}cobalt(III) perchlorate methanol monosolvate

In the title complex, [Co(C16H14N2O2)(C5H4ClN)2]ClO4·CH3OH, the CoIII ion is in a slightly distorted octahedral CoN4O2 coordination environment with the two 4-chloropyridine ligands in a trans arrangement