A Simple Hydrophilic Palladium(II) Complex as a Highly Efficient Catalyst for Room Temperature Aerobic Suzuki Coupling Reactions in Aqueous Media

A study on room temperature Suzuki cross-coupling in an aqueous medium was carried out using a simple hydrophilic palladium (II) complex, trans-PdCl2(NH2CH2COOH)2 as catalyst in the presence of K2CO3 in air. This approach with a comparatively inexpensive and hydrophilic catalyst, mild reaction condition and aqueous media exhibits excellent catalytic activity towards the Suzuki coupling of aryl bromides and arylboronic acids, and good yields were obtained in the Suzuki coupling of activated aryl chlorides

Highly Stereoselective Cyclopropanation of Olefins Catalyzed by a Novel <i>C</i>₃-Symmetric Arsine

<div><p></p><p>A novel <i>C</i>₃-symmetric arsine was employed in the one-pot cyclopropanation of olefins with carbonyl-stabilized arsonium ylides formed in situ from phenacyl bromide in the presence of NaHCO₃. This new arsine demonstrates good stereoselectivity and activity in the one-pot cyclopropanation of arylidenemalononitrile.</p> <p>[Supplementary materials are available for this article. Go to the publisher's online edition of <i>Synthetic Communications</i>® for the following free supplemental resource(s): Full experimental and spectral details.]</p> </div

Efficient synthesis of fluoro-containing liquid crystal materials via Pd-catalysed room temperature aerobic Suzuki reactions in aqueous media

<div><p>A series of fluoro-containing liquid crystal materials were synthesised at room temperature under aerobic conditions in excellent yields starting from fluoro-containing phenylboronic acids with aryl halides in the presence of a simple hydrophilic <i>trans</i>-PdCl₂(NH₂CH₂COOH)₂ as catalyst via aqueous media Suzuki cross-coupling reactions. Details relevant to the above reactions and to the reaction sequences adopted to get the corresponding fluoro-containing liquid crystal materials are presented. The structures of above catalyst and liquid crystal materials were characterised by element analyses, electrospray mass spectra, ¹H NMR and ¹³C NMR.</p></div