122 research outputs found

    Electronic governance technologies in the system of providing administrative services

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    The practice of using the term “electronic governance” does not differentiate the concepts of the subject of management, that is, the three branches of government, with forms, processes and technologies of governance, which is not correct, since the use of information technology in state activities is not a top priority. On the other hand, electronic governance technologies cannot be considered separately from the automated governance processes as well as electronic governance technologies are not a supplement or an analogue of the traditional state, as intended to communicate by means of electronic governance technologies to increase the efficiency of the entire system of public administration, in particular in the system of administrative services

    Adaptation of domestic state governance to international governance models

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    The purpose of the article is to provide the evolving international trends of modern management models and authorial vision of model of state governance system in Ukraine, its subsystems, in particular, the system of provision of administrative services that is appropriate for the contemporary times. Methodology. On the basis of scientific and theoretical approaches to the definitions of terms “state governance” and “public governance”, there was an explanation of considerable difference between them and, taking into consideration, the mentality of Ukrainian society and peculiar weak side in self-organization, the authors offered to form authorial model of governance on the basis of historically traditional for Ukraine model of state governance and to add some elements of management concepts that proved their significance, efficiency and priority in practice. Results. The authors emphasized the following two prevailing modern management models in the international practice: “new state management” and “good governance”. The first concept offered for consideration served as a basis for the semantic content of state activity that reflects more the state of administrative reformation. Practical meaning. A practical introduction of management to the domestic model of governance creates the range of contradictions that do not allow implementing herein concept. Pursuant to authors, the second one allows in considerable measure to reform state governance, considering historically developed peculiarities of this model. Moreover, the involvement of concept herein into introduction of informational and communicational technologies in the process of governance eliminates the necessity of power decentralization, it allows to form real net structure and, at the same, to keep vertical power structure, to involve citizens for formation and taking of management decisions, to form electronic communicational channel of feedback, to provide citizens with electronic administrative services. All indicated advantages of the concept certify about the necessity to reform state governance exactly in this field. Meaning/ Distinction. This article raises a question about the significance of formation and sequence of state policy in Ukraine aimed at creating an information-oriented society, space, as well as informational and technological infrastructure

    Net structure of subject-to-subject relations in the management of the system of administrative services provision

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    The purpose of the work is to form the net structure of management of the system of administrative services provision on the basis of implementation of subject-to-subject interactions between state sector and civil society. Methodology. The methodology basis for the investigation is the abstract-logical analysis of theoretical and methodological backgrounds for management of relations and interactions. For the theoretical generalization and formation of net structure, there are used scientific recommendations of Ukrainian scientists regarding the necessity to implement subject-to-subject relations in the system of administrative services provision. Results. The investigations allowed confirming that the hierarchical structure of the state governance system does not give an opportunity to implement equal interaction between a subject of provision and a subject of an appeal as these relations have one – way communication and the feedback channel has a formal character. Moreover, the civil society is not considered by state sector to be a source of methods and ways to develop the system of state governance, in particular, the management system of administrative services provision. Practical meaning. The net structure of management will allow implementing the subject-subject relations in the system, under which the actions of the subject of provision – that means state sector – will be directed to the realization of rights and interests of the subjects of appeal. In their turn, apart from the performance of all legislative responsibilities that they should perform, they can carry out activities directed to the development of management activity in the system of administrative services provision and the whole system of state governance as an integral system of management. Meaning/Distinction. The provided model of the net structure will allow involving citizens in the processes of state governance and increasing the impact of the civil sector during the making of state and management decisions and, as a result, to confirm subject-to-subject positions in the relations

    Peculiarities of the dielectric properties of ternary 0.5(Y0.1Zr0.9O2) - 0.5(0.6SrTiO3 - 0.4BiScO3) ceramic system

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    Ceramic samples of ternary 0.5(Y0.1Zr0.9O2) - 0.5(0.6SrTiO3 - 0.4BiScO3) system consisting of individual Y0.1Zr0.9O2 and 0.6SrTiO3 - 0.4BiScO3 subsystems were synthesized via solid-state processing techniques. By XRD analysis, a coexistence of tetragonal P42/nmc phase related to the Y0.1Zr0.9O2 subsystem, and cubic Pm3̅m and tetragonal P4mm phases associated with the 0.6SrTiO3 - 0.4BiScO3 subsystem was foun

    Electric field effect on variable-range hopping conductivity in Bi1.9Lu0.1Te3

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    Electric field effect on low-temperature electrical resistivity of n-type Bi1.9Lu0.1Te3 was examined and analyzed. It was found that with decreasing temperature from 35 down to 2.5 K, the conductivity mechanism changes from metal type to semiconductor one resulting in appearance of minimum in the specific electrical resistivity,

    Anisotropic thermoelectric properties of Bi1.9Lu0.1Te2.7Se0.3 textured via spark plasma sintering

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    An onset of intrinsic conductivity observed above Td ≈ 410 K results in appearance of maxima in the temperature dependences of the specific electrical resistivity, the Seebeck coefficient and the thermoelectric figure-of-merit coefficient and minimum in the temperature dependence of the total thermal conductivity. The intrinsic conductivity is harmful for the thermoelectric efficiency enhancement since thermal excitation of the electron-hole pairs reduces the Seebeck coefficient and increases the thermal conductivit

    Sustainable Closed-Loop Mask Supply Chain Network Design Using Mathematical Modeling and a Fuzzy Multi-Objective Approach

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    The outbreak of the deadly coronavirus, which is increasing the number of victims every day, has created many changes in today�s world. The use of various masks is the most important social tool against this virus. Given the importance of rapid and quality supply of masks in the current situation, it is necessary to study supply chain in particular. In this research, the design of a closed chain supply chain network for different types of masks is assessed. The studied supply chain includes suppliers, manufacturers, distributors, and retailers in the forward flow and collection centers, separate centers, recycling centers, and disposal centers in the backward flow. In this regard, a multi-objective mathematical model with the objectives of increasing the total profit and reducing the total environmental impact, and maximizing social responsibility is presented. The optimization of this mathematical model has been done using a fuzzy optimization approach in GAMS software. The results of this study show that maximizing the total profit and minimizing the environmental effects and maximizing social responsibility are in contrast to each other. In addition, the sensitivity analysis indicated that the customers� demand can affect all aspects of the sustainable supply chain simultaneously

    Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme

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    Detailed structural comparisons of sperm-specific glyceraldehyde 3-phosphate dehydrogenase, spermatogenic (GAPDHS) and the somatic glyceraldehyde 3-phosphate dehydrogenase (GAPDH) isozyme should facilitate the identification of selective GAPDHS inhibitors for contraceptive development

    Countering Extremism and Terrorism Among Youth — the Age of Digitalization

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    This study is based on the thesis that ensuring a favorable socio-political environment is one of the priority tasks of both society as a whole and law enforcement agencies of the state. The study is aimed at studying the situation of young people as the most vulnerable representatives of society in the face of dangerous ideological phenomena, unable to withstand these challenges.Aim. Identify measures that can counteract extremism and terrorism in the digital space among young people.Tasks. Consider the current legislation of the Russian Federation, on the basis of which educational and career guidance activities are carried out among the younger generation. To study the practice of applying measures aimed at countering extremism and terrorism. Evaluate the measures applied in practice and make suggestions for their improvement and updating.Methods. The current regulatory legal acts that are used in the implementation of educational programs to counter extremism and terrorism are analyzed. Career-oriented practices, programs of higher and additional education applied on the territory of the Russian Federation are also subject to consideration.Results. Within the framework of higher educational institutions, active work is carried out with students, which is expressed both in the preparation of scientific and pedagogical personnel for subsequent work with students, and information and discussion platforms are organized. Particular attention is paid to the work to involve students in practical activities in the framework of security.Conclusions. Information and educational work with young people in the framework of countering extremism and terrorism is carried out in sufficient volume. But the measures that can ensure the safety of the younger generation on the Internet are not sufficient, which it seems possible to make up for by creating and spreading the practices of cyber teams and involving students in working with digital platforms under the guidance of mentors from among the scientific and pedagogical staff of educational institutions

    Development and Implementation of a High Throughput Screen for the Human Sperm-Specific Isoform of Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDHS)

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    Glycolytic isozymes that are restricted to the male germline are potential targets for the development of reversible, non-hormonal male contraceptives. GAPDHS, the sperm-specific isoform of glyceraldehyde-3-phosphate dehydrogenase, is an essential enzyme for glycolysis making it an attractive target for rational drug design. Toward this goal, we have optimized and validated a high-throughput spectrophotometric assay for GAPDHS in 384-well format. The assay was stable over time and tolerant to DMSO. Whole plate validation experiments yielded Z’ values >0.8 indicating a robust assay for HTS. Two compounds were identified and confirmed from a test screen of the Prestwick collection. This assay was used to screen a diverse chemical library and identified fourteen small molecules that modulated the activity of recombinant purified GAPDHS with confirmed IC50 values ranging from 1.8 to 42 µM. These compounds may provide useful scaffolds as molecular tools to probe the role of GAPDHS in sperm motility and long term to develop potent and selective GAPDHS inhibitors leading to novel contraceptive agents
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