A survey of dog behavior modification practice in the UK: Who is offering it, what methods are they using and how effective do their clients perceive practitioners to be?

Thousands of dogs are relinquished each year in the UK owing to behavioral problems. Hence, there is a clear role for behavior modification therapy in the mitigation of this canine welfare risk. Since statutory regulation and a universal register of canine professionals (CPs) does not yet exist in the UK, it remains unclear who is offering such therapy, which behaviors are being treated, what types of approaches various CPs may be taking and the success (or otherwise) CPs are having. This study aimed to provide some insight into these issues from the perspective of pet dog owners (clients).An online survey of 235 participants showed that the primary reason for seeking behavior help from a CP was related to aggression, although often more than one issue was reported. Regardless of the behavior problem, no significant differences were found for the type of CP consulted (dog trainer versus behaviorist). Furthermore, in the client's opinion, there were no significant differences between CP types in their ability to improve their dog's unwanted behavior. Interestingly, behaviorists were significantly more likely than dog trainers to use ‘reward-based’ methods over ‘balanced training’ (balanced being a mix of reward and punishment; =8.226, df=1, p=0.004).In conclusion, in the current UK vacuum of statutory regulation, clients are just as likely to employ a trainer as a behaviorist, regardless of their dog's unwanted behavior. However, both CP types were equally able to facilitate behavior improvement, as reported by the client, regardless of the type of training methods (reward-based versus balanced) adopted. This study raises further questions to be explored including the client's opinion of the extent to which the ends (behavior outcomes) justify the means (e.g. punitive training methods which are likely to be aversive for the dog). Also, the general public's understanding of the potential welfare implications of the type of behavior modification plan they may or may not choose to follow

A survey of dog behavior modification practice in the UK: Who is offering it, what methods are they using and how effective do their clients perceive practitioners to be?

Thousands of dogs are relinquished each year in the UK owing to behavioral problems. Hence, there is a clear role for behavior modification therapy in the mitigation of this canine welfare risk. Since statutory regulation and a universal register of canine professionals (CPs) does not yet exist in the UK, it remains unclear who is offering such therapy, which behaviors are being treated, what types of approaches various CPs may be taking and the success (or otherwise) CPs are having. This study aimed to provide some insight into these issues from the perspective of pet dog owners (clients). An online survey of 235 participants showed that the primary reason for seeking behavior help from a CP was related to aggression, although often more than one issue was reported. Regardless of the behavior problem, no significant differences were found for the type of CP consulted (dog trainer versus behaviorist). Furthermore, in the client's opinion, there were no significant differences between CP types in their ability to improve their dog's unwanted behavior. Interestingly, behaviorists were significantly more likely than dog trainers to use ‘reward-based’ methods over ‘balanced training’ (balanced being a mix of reward and punishment; =8.226, df=1, p=0.004). In conclusion, in the current UK vacuum of statutory regulation, clients are just as likely to employ a trainer as a behaviorist, regardless of their dog's unwanted behavior. However, both CP types were equally able to facilitate behavior improvement, as reported by the client, regardless of the type of training methods (reward-based versus balanced) adopted. This study raises further questions to be explored including the client's opinion of the extent to which the ends (behavior outcomes) justify the means (e.g. punitive training methods which are likely to be aversive for the dog). Also, the general public's understanding of the potential welfare implications of the type of behavior modification plan they may or may not choose to follow

The importance of identified cause-of-death information being available for public health surveillance, actions and research

An amendment to the South African Births and Deaths Registration Act has compromised efforts to strengthen local mortality surveillance to provide statistics for small areas and enable data linkage to provide information for public health actions. Internationally it has been recognised that a careful balance needs to be kept between protecting individual patient confidentiality and enabling effective public health intelligence to guide patient care and service delivery and prevent harmful exposures. This article describes the public health benefits of a local mortality surveillance system in the Western Cape Province, South Africa (SA), as well as its potential for improving the quality of vital statistics data with integration into the national civil registration and vital statistics system. It also identifies other important uses for identifiable cause-of-death data in SA that have been compromised by this legislation

The importance of identified cause-of-death information being available for public health surveillance, actions and research

An amendment to the South African Births and Deaths Registration Act has compromised efforts to strengthen local mortality surveillance to provide statistics for small areas and enable data linkage to provide information for public health actions. Internationally it has been recognised that a careful balance needs to be kept between protecting individual patient confidentiality and enabling effective public health intelligence to guide patient care and service delivery and prevent harmful exposures. This article describes the public health benefits of a local mortality surveillance system in the Western Cape Province, South Africa (SA), as well as its potential for improving the quality of vital statistics data with integration into the national civil registration and vital statistics system. It also identifies other important uses for identifiable cause-of-death data in SA that have been compromised by this legislation.

What are the causal effects of breastfeeding on IQ, obesity and blood pressure? Evidence from comparing high-income with middle-income cohorts

Background A novel approach is explored for improving causal inference in observational studies by comparing cohorts from high-income with low- or middle-income countries (LMIC), where confounding structures differ. This is applied to assessing causal effects of breastfeeding on child blood pressure (BP), body mass index (BMI) and intelligence quotient (IQ)

Enhancement of red blood cell transfusion compatibility using CRISPR‐mediated erythroblast gene editing

Regular blood transfusion is the cornerstone of care for patients with red blood cell (RBC) disorders such as thalassaemia or sickle-cell disease. With repeated transfusion, alloimmunisation often occurs due to incompatibility at the level of minor blood group antigens. We use CRISPR-mediated genome editing of an immortalised human erythroblast cell line (BEL-A) to generate multiple enucleation competent cell lines deficient in individual blood groups. Edits are combined to generate a single cell line deficient in multiple antigens responsible for the most common transfusion incompatibilities: ABO (Bombay phenotype), Rh (Rhnull), Kell (K0), Duffy (Fynull), GPB (S−s−U−). These cells can be differentiated to generate deformable reticulocytes, illustrating the capacity for coexistence of multiple rare blood group antigen null phenotypes. This study provides the first proof-of-principle demonstration of combinatorial CRISPR-mediated blood group gene editing to generate customisable or multi-compatible RBCs for diagnostic reagents or recipients with complicated matching requirements