What kind of individual support activities in interventions foster pre-service and beginning teachers’ self-efficacy? A meta-analysis

During the early stages of the teaching profession, pre-service and beginning teachers often participate in individual support activities intended to develop their teacher self-efficacy. These individual support activities (modeling, feedback on lesson plans or lessons, and reflection) are provided as part of an intervention by a mentor, cooperating teacher, instructor, or supervisor. We conducted a meta-analysis to investigate the effectiveness of these interventions and the individual support activities for pre-service and beginning teachers’ self-efficacy. We found a medium-sized overall effect of interventions on teacher self-efficacy based on 28 studies (49 effect sizes) in our meta-analysis. Providing feedback on lesson plans amplified the intervention effect (large effect). However, this moderator effect slightly missed the significance level of 0.05. The moderator effect of providing feedback on lesson plans was stable after controlling for mastery experiences and methodological moderator variables. Implications for future interventions regarding teacher self-efficacy for early career teachers are discussed

Zeitverwendung im Alltag: Zusatzinstrumente zum ifb-Zeitverwendungstagebuch

Die vorliegenden Instrumente zur Messung der Zeitverwendung im Alltag wurden im Rahmen des DFG geförderten Projekts "Innerfamiliale Arbeitsteilung als Prozess" entwickelt und als Kontrollinstrument und potenzielle methodologische Alternative zum ifb-Zeitverwendungstagebuch im Frühjahr 2005 erstmalig im Rahmen von Paarbefragungen (n = 98 Personen) getestet. Die Zielsetzung dieses Vorhabens war es, ein innovatives Erhebungsinstrument zur Messung der Arbeitsteilung von Paaren im Beziehungsverlauf zu entwickeln. Das vorliegende Dokument enthält die Zusatzinstrumente (1) Standarddemografie, (2) Zeitschätzung und (3) Einschätzung der Aufgabenteilung (TPI). (ICI2

Zeitverwendung im Alltag: das ifb-Zeitverwendungstagebuch

Das Dokument enthält das ifb-Zeitverwendungstagebuch, welches im Rahmen des DFG-Projekts "Innerfamiliale Arbeitsteilung als Prozess" entstand. Gegenstand dieser Untersuchung ist der Prozess der familialen Arbeitsteilung in der Beziehungs- und Familienentwicklung. Das Forschungsprojekt greift dabei auf Theorien der kontext- und situationsbezogenen (Wahl-)Handlungen interdependenter Akteure zurück und versucht nicht nur die Entwicklung von Umfang und Art der geschlechtsspezifischen Tätigkeiten quantitativ im Längsschnitt zu bestimmen, sondern auch die damit verbundenen dynamischen Entscheidungsprozesse qualitativ zu entschlüsseln. (ICI2

Tijdbesteding in het leven van alledag: das ifb-Zeitverwendungstagebuch (niederländische Übersetzung)

Dieser Materialienband enthält die niederländische Übersetzung des ifb-Zeitverwendungstagebuches (ifb-Materialien 3/2005). Die Übersetzung wurde erstellt von Ida van der Woude

68Ga-PSMA-11 PET/MR Can Be False Positive in Normal Prostatic Tissue

Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein expressed in the cytosol of normal prostate tissue and highly overexpressed on the membrane of prostate cancer, therefore increasingly used to image prostate cancer. We report a case of a 65-year-old man with two focal PSMA-positive areas on a Ga-PSMA-11 PET/MR, one corresponding to a prostate carcinoma (Gleason score 4 + 3) and another region without any evidence of malignancy, but with corresponding high PSMA-expression on immunohistochemistry

Publisher Correction: Coherent diffractive imaging of single helium nanodroplets with a high harmonic generation source

In the original version of this Article, the affiliation for Luca Poletto was incorrectly given as ‘European XFEL GmbH, Holzkoppel 4, 22869 Schenefeld, Hamburg, Germany’, instead of the correct ‘CNR, Istituto di Fotonica e Nanotecnologie Padova, Via Trasea 7, 35131 Padova, Italy’. This has now been corrected in both the PDF and HTML versions of the Article

Thin-disk laser-pumped OPCPA system delivering 4.4 TW few-cycle pulses

We present an optical parametric chirped pulse amplification (OPCPA) system delivering 4.4 TW pulses centered at 810 nm with a sub-9 fs duration and a carrier-envelope phase stability of 350 mrad. The OPCPA setup pumped by sub-10 ps pulses from two Yb:YAG thin-disk lasers at 100 Hz repetition rate is optimized for a high conversion-efficiency. The terawatt pulses of the OPCPA are utilized for generating intense extreme ultraviolet (XUV) pulses by high-order harmonic generation, achieving XUV pulse energies approaching the microjoule level. © 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreemen

Development and external validation of a multivariable [68^{68}Ga]Ga-PSMA-11 PET-based prediction model for lymph node involvement in men with intermediate or high-risk prostate cancer

PURPOSE To develop and evaluate a lymph node invasion (LNI) prediction model for men staged with [$^{68}$Ga]Ga-PSMA-11 PET. METHODS A consecutive sample of intermediate to high-risk prostate cancer (PCa) patients undergoing [$^{68}$Ga]Ga-PSMA-11 PET, extended pelvic lymph node dissection (ePLND), and radical prostatectomy (RP) at two tertiary referral centers were retrospectively identified. The training cohort comprised 173 patients (treated between 2013 and 2017), the validation cohort 90 patients (treated between 2016 and 2019). Three models for LNI prediction were developed and evaluated using cross-validation. Optimal risk-threshold was determined during model development. The best performing model was evaluated and compared to available conventional and multiparametric magnetic resonance imaging (mpMRI)-based prediction models using area under the receiver operating characteristic curves (AUC), calibration plots, and decision curve analysis (DCA). RESULTS A combined model including prostate-specific antigen, biopsy Gleason grade group, [$^{68}$Ga]Ga Ga-PSMA-11 positive volume of the primary tumor, and the assessment of the [$^{68}$Ga]Ga-PSMA-11 report N-status yielded an AUC of 0.923 (95% CI 0.863-0.984) in the external validation. Using a cutoff of  ≥ 17%, 44 (50%) ePLNDs would be spared and LNI missed in one patient (4.8%). Compared to conventional and MRI-based models, the proposed model showed similar calibration, higher AUC (0.923 (95% CI 0.863-0.984) vs. 0.700 (95% CI 0.548-0.852)-0.824 (95% CI 0.710-0.938)) and higher net benefit at DCA. CONCLUSIONS Our results indicate that information from [$^{68}$Ga]Ga-PSMA-11 may improve LNI prediction in intermediate to high-risk PCa patients undergoing primary staging especially when combined with clinical parameters. For better LNI prediction, future research should investigate the combination of information from both PSMA PET and mpMRI for LNI prediction in PCa patients before RP

Quantitative imaging parameters to predict the local staging of prostate cancer in intermediate- to high-risk patients

Objectives: PSMA PET/MRI showed the potential to increase the sensitivity for extraprostatic disease (EPD) assessment over mpMRI; however, the interreader variability for EPD is still high. Therefore, we aimed to assess whether quantitative PSMA and mpMRI imaging parameters could yield a more robust EPD prediction. Methods: We retrospectively evaluated PCa patients who underwent staging mpMRI and [68Ga]PSMA-PET, followed by radical prostatectomy at our institution between 01.02.2016 and 31.07.2019. Fifty-eight cases with PET/MRI and 15 cases with PET/CT were identified. EPD was determined on histopathology and correlated with quantitative PSMA and mpMRI parameters assessed by two readers: ADC (mm2/1000 s), longest capsular contact (LCC, mm), tumor volume (cm3), PSMA-SUVmax and volume-based parameters using a fixed threshold at SUV > 4 to delineate PSMAtotal (g/ml) and PSMAvol (cm3). The t test was used to compare means, Pearson's test for categorical correlation, and ROC curve to determine the best cutoff. Interclass correlation (ICC) was performed for interreader agreement (95% CI). Results: Seventy-three patients were included (64.5 ± 6.0 years; PSA 14.4 ± 17.1 ng/ml), and 31 had EPD (42.5%). From mpMRI, only LCC reached significance (p = 0.005), while both volume-based PET parameters PSMAtotal and PSMAvol were significantly associated with EPD (p = 0.008 and p = 0.004, respectively). On ROC analysis, LCC, PSMAtotal, and PSMAvol reached an AUC of 0.712 (p = 0.002), 0.709 (p = 0.002), and 0.718 (p = 0.002), respectively. ICC was moderate-good for LCC 0.727 (0.565-0.828) and excellent for PSMAtotal and PSMAvol with 0.944 (0.990-0.996) and 0.985 (0.976-0.991), respectively. Conclusions: Quantitative PSMA parameters have a similar potential as mpMRI LCC to predict EPD of PCa, with a significantly higher interreader agreement. Keywords: Extracapsular extension; PSMA PET (MRI) Prostate cancer; Prediction; Seminal vesicle infiltration