Registro de neoplasias caninas diagnosticadas en la Unidad de Prácticas Veterinarias, Universidad Maza, Mendoza, Argentina, 2006-2020

This study aims to present the relative frequency of canine tumors diagnosed at a Veterinary Practice Unit, University service with regional scope, in the period 2006- 2020. A retrospective analysis was carried out based on the information extracted from the medical records. In total, 4500 clinical histories were consulted, among which 238 cases of canine tumors were diagnosed. Information about epidemiological aspects was recorded. Neoplasms were confirmed by histological or cytological analysis in 49% of the cases, which were mostly malignant (60%). In the canine population under study, the animals manifested tumors primarily between 9 and 10 years of age. The 49.5% of the animals with neoplasia were of purebreds, represented mostly by Argentinian Dogo with squamous cell carcinoma and hemangiosarcoma, and boxer with mast cell tumor and multicentric lymphoma, which suggests a predisposition of certain breeds to some type of neoplasms. The most common tumor was Transmissible Venereal Tumor TVT (16% of the total neoplasms), presented mainly in mixed breeds. Next in order of frequency, mast cell tumors and hemangiosarcoma (8.4% each), followed by squamous cell carcinoma (7.6%). The registration of animal tumors is important to delineate the behavior of cancer in the canine population and to provide data that can be compared with human ones, useful for identifying possible risk factors. This study constitutes a preliminary step to characterize and understand the occurrence of canine tumors in the region.Este estudio tiene como objetivo presentar la frecuencia relativa de tumores caninos diagnosticados en una Unidad de Prácticas Veterinarias, servicio universitario de ámbito regional, en el periodo 2006- 2020. El análisis retrospectivo se realizó a partir de la información extraída de las historias clínicas, se consultaron 4500 en total, que evidenciaron 238 casos de tumores caninos. Se registró la información disponible acerca de aspectos epidemiológicos. Las neoplasias se confirmaron mediante análisis histológico o citológico en el 49% de los casos, los que en su mayoría fueron malignos (60%). En la población canina objeto de estudio, los animales manifestaron tumores principalmente entre los 9 y 10 años de edad. El 49,5% de los animales con neoplasia eran de raza pura, representados en su mayoría por Dogo Argentino con carcinoma de células escamosas y hemangiosarcoma, y bóxer con mastocitoma y linfoma multicéntrico, lo que sugiere una predisposición de ciertas razas a algún tipo de neoplasias. El tumor más frecuente fue el Tumor Venéreo Transmisible TVT (16% del total), presentado principalmente en mestizos. Le siguen en orden de frecuencia el mastocitoma y el hemangiosarcoma (8,4% cada uno), seguidos del carcinoma de células escamosas (7,6%). El registro de tumores en animales es importante para delinear el comportamiento del cáncer en la población canina y proporcionar datos que puedan compararse con los humanos, lo cual es útil para identificar posibles factores de riesgo. Este estudio constituye un paso preliminar para caracterizar y comprender la ocurrencia de tumores caninos en la región

Registry of canine neoplasias diagnosed at the Veterinary Practice Unit, Maza University, Argentina, 2006-2020

Este estudio tiene como objetivo presentar la frecuencia relativa de tumores caninos diagnosticados en una Unidad de Prácticas Veterinarias, servicio universitario de ámbito regional, en el periodo 2006- 2020. El análisis retrospectivo se realizó a partir de la información extraída de las historias clínicas, se consultaron 4500 en total, que evidenciaron 238 casos de tumores caninos. Se registró la información disponible acerca de aspectos epidemiológicos. Las neoplasias se confirmaron mediante análisis histológico o citológico en el 49% de los casos, los que en su mayoría fueron malignos (60%). En la población canina objeto de estudio, los animales manifestaron tumores principalmente entre los 9 y 10 años de edad. El 49,5% de los animales con neoplasia eran de raza pura, representados en su mayoría por Dogo Argentino con carcinoma de células escamosas y hemangiosarcoma, y bóxer con mastocitoma y linfoma multicéntrico, lo que sugiere una predisposición de ciertas razas a algún tipo de neoplasias. El tumor más frecuente fue el Tumor Venéreo Transmisible TVT (16% del total), presentado principalmente en mestizos. Le siguen en orden de frecuencia el mastocitoma y el hemangiosarcoma (8,4% cada uno), seguidos del carcinoma de células escamosas (7,6%). El registro de tumores en animales es importante para delinear el comportamiento del cáncer en la población canina y proporcionar datos que puedan compararse con los humanos, lo cual es útil para identificar posibles factores de riesgo. Este estudio constituye un paso preliminar para caracterizar y comprender la ocurrencia de tumores caninos en la región.This study aims to present the relative frequency of canine tumors diagnosed at a Veterinary Practice Unit, University service with regional scope, in the period 2006- 2020. A retrospective analysis was carried out based on the information extracted from the medical records. In total, 4500 clinical histories were consulted, among which 238 cases of canine tumors were diagnosed. Information about epidemiological aspects was recorded. Neoplasms were confirmed by histological or cytological analysis in 49% of the cases, which were mostly malignant (60%). In the canine population under study, the animals manifested tumors primarily between 9 and 10 years of age. The 49.5% of the animals with neoplasia were of purebreds, represented mostly by Argentinian Dogo with squamous cell carcinoma and hemangiosarcoma, and boxer with mast cell tumor and multicentric lymphoma, which suggests a predisposition of certain breeds to some type of neoplasms. The most common tumor was Transmissible Venereal Tumor TVT (16% of the total neoplasms), presented mainly in mixed breeds. Next in order of frequency, mast cell tumors and hemangiosarcoma (8.4% each), followed by squamous cell carcinoma (7.6%). The registration of animal tumors is important to delineate the behavior of cancer in the canine population and to provide data that can be compared with human ones, useful for identifying possible risk factors. This study constitutes a preliminary step to characterize and understand the occurrence of canine tumors in the region.Fil: Caliri Barchiesi, Martina Noel. Universidad "juan Agustin Maza". Facultad de Cs.veterinarias y Ambientales. Cátedra de Genetica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza; ArgentinaFil: Ferré, Daniela Marisol. Universidad "juan Agustin Maza". Facultad de Cs.veterinarias y Ambientales. Cátedra de Genetica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza; ArgentinaFil: Palma Leotta, María Evangelina. Universidad "juan Agustin Maza". Facultad de Cs.veterinarias y Ambientales. Cátedra de Genetica; ArgentinaFil: Gorla, Nora Bibiana Maria. Universidad "juan Agustin Maza". Facultad de Cs.veterinarias y Ambientales. Cátedra de Genetica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza; Argentin

Recent advances in thermosensitive hydrogels as drug delivery systems: A review

Polymers that exhibit physicochemical responses to stimuli have been widely explored as potential drug delivery systems. Different kind of stimuli investigated to date includes, for example, chemical substances and changes in temperature, pH and electric fields. Polymers that exhibit dramatic changes in their behavior in an aqueous solution at temperatures close to the body temperature are of particular interest in drug delivery and biomedical applications. Thermosensitive polymers have a wide range of applications, specially, the thermosensitive triblock copolymers because they exhibit unique aqueous solution properties, biodegradability and biocompatibility. These copolymers can be designed to be used as potential drug delivery systems for therapeutic protein drugs or poorly water soluble drugs. This article reviews the applications of polymer solutions with the ability to form in situ implants under temperature changes, in areas of interest to biomedical, pharmacist and engineer scientists. Recent advantages on thermosensitive and biodegradable polymers are discussed to give a wide overview of the available strategies to modify them in order to make them suitable for potential applications in health products.Fil: Bermudez, Jose Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones para la Industria Química. Universidad Nacional de Salta. Facultad de Ingeniería. Instituto de Investigaciones para la Industria Química; ArgentinaFil: Quinteros, Daniela Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica; ArgentinaFil: Grau, Ricardo José Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Allemandi, Daniel Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica; ArgentinaFil: Palma, Santiago Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica; Argentin

Estado del arte de la incidencia de los beneficios incluidos en las reformas tributarias de los últimos 12 años frente al recaudo del impuesto sobre la renta para personas naturales

Cuando se plantean metas alrededor de una idea de investigacion, se discute como sera organizado y que cualificaciones y/o cuantificaciones involucradas para defender la teoria a plantear y que tipo de practicas de desarrollaran alrededor de esta. Por ello, se constituye un proyecto que incluye el estudio y la valoracion de un camino compuesto por un periodo de 12 años y una produccion cientifica que cuenta con condiciones economicas, fiscales, tributarias, sociales que se imparten alrededor de politicas que establecen la constitucion de los tributos para el recaudo del impuesto sobre la renta para personas naturales en Colombia. Estructurando así, el comparativo entre las deficiencias, los beneficios, el nivel de recaudo y su incidencia frente a estructuras consolidadas como lo son el recaudo del impuesto sobre la renta neto y su aporte frente al gasto público; situación que conlleva a políticas que otorguen mejores resultados frente al recaudo, la disminución de la de la evasión, la elusión, el lavado de activos, entre otros; por medio del control fiscal administrado por la Dirección de Impuestos y Aduanas Nacionales DIAN.When goals are raised around a research idea, it is discussed how it will be organized and what qualifications and / or quantifications involved to defend the theory to be proposed and what type of practices will be developed around it. For this reason, a project is constituted that includes the study and assessment of a path composed of a period of 12 years and a scientific production that has economic, fiscal, tax, social conditions that are taught around policies that new the constitution of the taxes for the collection of the income tax for natural persons in Colombia. Thus structuring the comparison between the deficiencies, the benefits, the level of collection and their incidence compared to consolidated structures such as the collection of net income tax and its contribution against public spending; situation that leads to policies that provide better results in the face of collection, reduction of evasion, avoidance, money laundering, among others; through fiscal control administered by the National Tax and Customs Directorate DIAN

Is the monoclonal spread of the ST258, KPC-3-producing clone being replaced in southern Italy by the dissemination of multiple clones of carbapenem nonsusceptible, KPC-3-producing Klebsiella pneumoniae?

Spread of carbapenemase-producing Klebsiella pneumoniae has been identified as an issue of serious worldwide concern from clinical and public health perspectives. Italy is an country endemic for and a reservoir of K. pneumoniae carbapenemases (KPC). Nineteen isolates of CR-Kp from 16 different patients admitted in two hospital of Palermo in the period April-May 2014 were studied. Seven of 16 isolates belonged to ST307, six to ST258 and three to ST273. All isolates were KPC-3 producers. Our data emphasize the increasing difficulties in controlling the spread of KPC-K

Los entornos virtuales de aprendizaje una alternativa de solución a los procesos educativos en tiempos de pandemia

A large part of the measures that countries adopted in the face of the pandemic crisis today are related to the suspension of face-to-face classes and it is here where virtuality acquires particular relevance. The traditional classroom is a potential source of contagion and, therefore, preventive measures against the transmission of this virus have included among their first actions the cancellation of face-to-face classes at all levels. For this reason, for several months we have had millions of people facing a new way of teaching and learning. The present research aimed to analyze virtual environments as an alternative solution to teaching-learning processes in times of pandemic, a non-experimental methodology was used, under a descriptive quantitative approach. Based on the results, it was possible to show that virtual learning environments have been an option for the majority of students, with advantages such as time to work or carry out other activities, saving money and organization through established work schedules, and an obstacle to Others, who do not have access to the internet or have the necessary resources to attend virtual classes, existing inequalities in the use of digital pedagogical technologies and resources, these inconveniences are manifested in relation to the type of management, educational level, the socioeconomic situation of the students, academic performance and support from the student's family.Gran parte de las medidas que los países adoptaron ante la crisis de la pandemia en la actualidad se relacionan con la suspensión de clases presenciales y es aquí donde la virtualidad adquiere particular relevancia. El salón tradicional de clases es un potencial foco de contagio y, por esto, las medidas preventivas contra la transmisión de este virus han incluido entre sus primeras acciones la cancelación de las clases presenciales a todos los niveles. Por esto, durante varios meses hemos tenido a millones de personas enfrentándose a un nuevo modo de enseñar y aprender. La presente investigación tuvo como objetivo analizar los entornos virtuales como una alternativa de solución a los procesos de enseñanza-aprendizaje en tiempos de pandemia, se empleó una metodología no experimental, bajo un enfoque cuantitativo de tipo descriptivo. En base a los resultados se pudo evidenciar que los entornos virtuales de aprendizaje han sido una opción para la mayoría de estudiantes, con ventajas como tiempo para trabajar o realizar otras actividades, ahorro de dinero y organización mediante cronogramas de trabajo establecidos, y un obstáculo para otros, quienes no tienen acceso a internet ni cuentan con los recursos necesarios para asistir a las clases virtuales, las desigualdades existentes en cuanto al uso de tecnologías y recursos pedagógicos digitales, estos inconvenientes se manifiestan en relación con el tipo de gestión, el nivel educativo, la situación socioeconómica de los estudiantes, el rendimiento académico y el apoyo por parte de la familia del estudiante

Case Report A Fatal Bloodstream Infection by Staphylococcus pettenkoferi in an Intensive Care Unit Patient

Coagulase negative staphylococci are increasingly recognized as leading pathogens in bacteremia, with incidence peaking in intensive care units. Interpretation of blood cultures that are positive for CoNS is often doubtful. We describe a fatal case of bacteremia by a newly recognized species of CoNS, Staphylococcus pettenkoferi, in an ICU patient

Estrogen Receptor Expression in Cutaneous Melanoma

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Endoscopic and Surgical Removal of Gastrointestinal Foreign Bodies in Dogs: An Analysis of 72 Cases

In emergency veterinary practice, gastrointestinal foreign body (GFB) removal is a common procedure that is performed with different techniques, such as endoscopy or surgery. The aims of this retrospective, multicentre, clinical study were to report the common locations and types of objects recovered and to investigate clinical factors and outcomes in dogs after surgical or endoscopic treatment for GFB removal. Records of dogs with a GFB diagnosis referred to the Teaching Veterinary Hospital or treated in three different veterinary hospitals from September 2017 to September 2019 were examined. The data obtained from each case included breed, age, clinical signs at presentation, duration of clinical signs, type and location of the GFB, treatment, length of hospitalisation and outcome. Seventy-two dogs were enrolled in the study. There were 42 males (58%) and 30 females (42%). The median age was 36 months (range: 3 months to 8 years). Endoscopic retrieval was performed in 56% of GFBs (located in the stomach or duodenum), whereas 44% of dogs underwent surgery. The type of FB detected varied greatly: kid toy (14%), metallic object/coin (13%), cloth (13%), sock (8%), ball (8%), plastic material (8%), peach stone (7%), fishhook (6%), sewing needle (4%), hair tie (4%), pacifier (3%), plant materials (3%) and others (9%). Moreover, the FBs were classified as sharp (13%, n = 9), pointed (33%, n = 24), blunt (26%, n = 19), or linear (28%, n = 20). In this study, 68% of FBs were localised in the stomach, 25% in the intestinal tract (50% duodenum, 28% jejunum, and 22% ileum), and 7% in both the stomach and small intestine. The type of GFB was not significantly associated with age, site or breed. There was a significant association between the type of GFB and sex: if the dog was male, there was a 38% probability of ingesting linear GFBs. The dog survival rate was 100% in cases treated by gastric endoscopic or surgical removal, 94% in cases treated with enterotomy and 33% in cases in which enterectomy was necessary. Enterectomy and multiple surgical sites were associated with a poor outcome. The presence of vomiting for more than 24 h was significantly associated with death

SARS-CoV-2 Infection Incidence and Outcome Before and After Full Vaccination in Patients With Monoclonal Gammopathy of Undetermined Significance

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