101 research outputs found

    Jordan symmetry reduction for conic optimization over the doubly nonnegative cone: theory and software

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    A common computational approach for polynomial optimization problems (POPs) is to use (hierarchies of) semidefinite programming (SDP) relaxations. When the variables in the POP are required to be nonnegative, these SDP problems typically involve nonnegative matrices, i.e. they are conic optimization problems over the doubly nonnegative cone. The Jordan reduction, a symmetry reduction method for conic optimization, was recently introduced for symmetric cones by Parrilo and Permenter [Mathematical Programming 181(1), 2020]. We extend this method to the doubly nonnegative cone, and investigate its application to known relaxations of the quadratic assignment and maximum stable set problems. We also introduce new Julia software where the symmetry reduction is implemented.Comment: 19 pages, titled change from earlier version. arXiv admin note: text overlap with arXiv:1908.0087

    Crystalluria and Urolithiasis in a Relatively Stone-Free Population

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    The occurrence of renal stone in South African blacks is extremely rare. Whites however are prone to calculi to the same extent as that reported in other Western communities. The nature of the particulate material and crystalluria in urine samples from the two population groups were investigated using a Coulter Counter and scanning electron microscope. In addition, 10 calculi obtained from black patients over a 5 year period were analysed. The particle size distribution curves obtained for normal black and white males were identical. The curves for normal black and white females were also identical but different from those for males. Black male stone formers had larger particles than their controls while the single black female stone former investigated had particles of the same size as female controls, but in greater numbers. Scanning electron microscopy revealed profuse amounts of crystalline NaCl, KCl and other salts in the urinary sediments of blacks. These were not observed in the specimens from whites nor in the black stone formers\u27 urines. Analysis of the calculi identified chemical and ultrastructural features similar to those observed in stones from whites. The hypothesis that the lower incidence of stone disease in blacks may be due to a high Na/Ca ratio is supported by our findings. It is suggested that various salts play a role in lowering the stone forming potential of such urines by a competitive substitution mechanism in which lattice calcium is displaced by sodium. It is also suggested that when urinary stone formation does occur in blacks, it does so via the same physicochemical mechanisms as in any other race group

    Co-expression of aroma liberating enzymes in a wine yeast strain

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    Thesis (Msc (Viticulture and Oenology. Institute for Wine Biotechnology))--University of Stellenbosch, 2009.Monoterpenes are important aroma compounds in certain grape varieties such as Muscat, Gewürztraminer and Riesling and are present as either odourless, glycosidically bound complexes or as free aromatic monoterpenes. These complexes occur as monoglucosides or, when present as diglycosides, most commonly as 6-O-α-L-arabinofuranosyl-β-D-glucopyranosides of mainly linalool, geraniol, nerol and citronellol. The release of monoterpenes from non-volatile glycosidically bound precursors occurs either by acid hydrolysis or enzymatic hydrolysis. High temperature acid hydrolysis causes a rearrangement of the monoterpene aglycones and a decrease in the aroma and changes in the aromatic characteristics of monoterpenes and is therefore not suitable. Enzymatic hydrolysis does not modify the monoterpene aglycones and can be an efficent method to release potentially volatile monoterpenes. α-L-arabinofuranosidase and β-glucosidase are important enzymes responsible for the liberation of monoterpene alcohols from their glycosides. Glycosidases from Vitis vinifera and Saccharomyces cerevisiae are severely inhibited by winemaking conditions and this leads to unutilized aroma potential, while commercial preparations of aroma liberating enzymes are crude extracts that often have unwanted and unpredictable side effects. It is therefore of interest to investigate alternative measures to release glycosidically bound monoterpenes to increase the floral aroma of wine without side activities that impact negatively on wine. Heterologous α-L-arabinofuranosidases and β-glucosidases have previously been expressed in S. cerevisiae and these studies have evaluated and found increased glycosidic activities against both natural and synthetic substrates. In this study, we expressed the Aspergillus awamori α-L-arabinofuranosidase (AwAbfB) in combination with either the β-glucosidases Bgl2 from Saccharomycopsis fibuligera or the BglA from Aspergillus kawachii in the industrial yeast strain S. cerevisiae VIN13 to facilitate the sequential enzymatic hydrolysis of monoterpene diglycosides. Enzyme assays and GC-FID (Gas Chromatography with a Flame Ionization Detector) results show a significant increase in the amount of free monoterpene concentrations under winemaking conditions in the strain co-expressing the AwAbfB and the Bgl2. The increases in free monoterpene levels obtained were similar to those obtained with a commercial enzyme preparation, LAFAZYM AROM. Sensorial evaluation confirmed the improvement in the wine aroma profile, particularly the floral character. This yeast strain permits a single culture fermentation which improves the sensorial quality and complexity of wine. Further investigations on the factors influencing the stability and reactivity of monoterpenes during alcoholic fermentation are needed

    A usability study on widget design for selecting boolean operations

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    Applying the correct set of Boolean operations is a fundamental task in constructive solid geometry (CSG), which is a staple in automated manufacturing systems. Although textual buttons and icons are the most common interfaces to apply such operations, these require an unnecessary cognitive load that hampers the solid modeling process. This study presents VennPad, a novel CSG widget that gathers all Boolean operations under the same user interface control element and is represented as a two-set Venn diagram. Contrary to conventional CSG widgets, VennPad supports a graphical interface that gives simultaneous access to several types of Boolean operations (intersection, union, difference, symmetric difference and split). A usability study was conducted to ascertain whether VennPad is a more natural interface compared to textual buttons and icon-based widgets for different solid modeling tasks. VennPad proved to be an effective interface to perform Boolean operations. Qualitative feedback places VennPad as the preferred interface, but efficiency results are operation dependent, thus, opening the way to new design iterations.info:eu-repo/semantics/publishedVersio

    The development of behavioral and endocrine abnormalities in rats after repeated exposure to direct and indirect stress

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    The present study compared the effects of direct and indirect stress on the behavior and hypothalamic-pituitary-adrenal axis of rats. Animals were placed in a two compartment box. In one compartment the direct stressed rat was subjected to electric foot shocks randomly applied for 10 minutes (0.5 mA of 1 s duration). In the adjacent compartment, the indirect stressed rats witnessed the application of these electric foot shocks. Our data showed substantial behavioral changes in the open field test, but limited effects in the elevated plus maze. The findings suggested that single and repeated stress exposure may have different consequences, that the effects of stress exposure may develop over time and persist for an extended period, and that both direct and indirect stressed rats displayed a hyposensitive HPA axis following acute restraint stress. Overall our observations moderately indicate direct exposure to elicit behavioral changes, and both direct and indirect exposure to stress to result in aberrations within the neuroendocrine system. With additional development our stress models may be considered for studying the complex interrelationship between an external stressor, and the experience of the organism

    A Usability Study on Widget Design for Selecting Boolean Operations

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    Applying the correct set of Boolean operations is a fundamental task in constructive solid geometry (CSG), which is a staple in automated manufacturing systems. Although textual buttons and icons are the most common interfaces to apply such operations, these require an unnecessary cognitive load that hampers the solid modeling process. This study presents VennPad, a novel CSG widget that gathers all Boolean operations under the same user interface control element and is represented as a two-set Venn diagram. Contrary to conventional CSG widgets, VennPad supports a graphical interface that gives simultaneous access to several types of Boolean operations (intersection, union, difference, symmetric difference and split). A usability study was conducted to ascertain whether VennPad is a more natural interface compared to textual buttons and icon-based widgets for different solid modeling tasks. VennPad proved to be an effective interface to perform Boolean operations. Qualitative feedback places VennPad as the preferred interface, but efficiency results are operation dependent, thus, opening the way to new design iterations.info:eu-repo/semantics/publishedVersio

    Resistance of Nguni, Bonsmara and Hereford cattle to ticks in a Bushveld region of South Africa

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    Counts of engorged female ticks on naturally infested cattle over a 2 year period, showed that indigenous Nguni cattle harboured significantly fewer Amblyomma hebraeum, Boophilus decoloratus and Hyalomma spp. during periods of peak abundance than either Bonsmara or Hereford cattle. Fewer abscesses, associated with tick bite, were also present in the Nguni cattle. Individual tick resistance indices, determined after artificial tick infestation in the field, could not be correlated with hair length, skin thickness or conglutinin titres. The consistently large percentage of Nguni cattle showing high tick resistance according to index determinations, indicates a superior level of natural immunity in this breed. The relative incidence of individuals in high, medium and low resistance classes reflected an increase in resistance with exposure to ticks and the potential for the selection for tick resistance within all 3 breeds.The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.lmchunu2014mn201

    The host preferences of Nuttalliella namaqua (Ixodoidea : Nuttalliellidae) : a generalist approach to surviving multiple host-switches

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    Nuttalliella namaqua has been described as a “living fossil” and the closest extant species to the ancestral tick lineage. It was previously proposed that the Nuttalliella lineage parasitized reptile-like mammals in the Permian and had to switch hosts several times due to mass or host lineage extinctions. Extant hosts include girdled lizards and murid rodents. The current study extends knowledge on the extant host range of N. namaqua using gut meal analysis of field collected specimens. Nymphs and females can parasitize a variety of reptiles that includes skinks, geckos and girdled lizards. Blood-meal from a hyrax was also detected in a specimen suggesting that N. namaqua could parasitize a broader range of mammals than the previously suggested murid rodents. Rather than being host specific, N. namaqua is proposed to be a generalist and the ability to switch and parasitize multiple hosts allowed it to survive multiple mass and host lineage extinctions.The Joy Liebenberg Trust (21/19/JT02) allocated to BM, an incentive funding for rated researchers grant from the National Research Foundation of South Africa (NRF-Mans 76499) and a South African National Research Foundation grant allocated to AL (NRF-Spain).http://link.springer.com/journal/10493hb2014ab201

    An update of the tsetse fly (Diptera: Glossinidae) distribution and African animal trypanosomosis prevalence in north-eastern KwaZulu-Natal, South Africa

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    An unpredicted outbreak of African animal trypanosomosis or nagana in 1990 in north-eastern KwaZulu-Natal necessitated an emergency control programme, utilising the extensive cattledipping system in the area, as well as a reassessment of the tsetse and trypanosomosis problem in the province. Since 1990, sporadic blood sampling of cattle at the dip tanks in the naganainfested areas were undertaken to identify trypanosome species involved and to determine the infection prevalence in cattle. The distribution and species composition of the tsetse populations in the area were also investigated. From November 2005 to November 2007 selected dip tanks were surveyed for trypanosome infection prevalence. During April 2005 to August 2009 the distribution and abundance of tsetse populations were assessed with odour-baited H traps. The tsetse and trypanosome distribution maps were updated and potential correlations between tsetse apparent densities (ADs) and the prevalence of trypanosomosis were assessed. Glossina brevipalpis Newstead and Glossina austeni Newstead were recorded in locations where they have not previously been collected. No significant correlation between tsetse relative abundance and nagana prevalence was found, which indicated complex interactions between tsetse fly presence and disease prevalence. This was epitomised by data that indicated that despite large differences in the ADs of G. austeni and G. brevipalpis, trypanosome infection prevalence was similar in all three districts in the area. This study clearly indicated that both tsetse species play significant roles in trypanosome transmission and that it will be essential that any control strategy, which aims at sustainable management of the disease, should target both species
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