Efektivitas Pendampingan dalam Produksi dan Pengunaan Insektisida Organik di Kelompok Tani Sumber Urip Malang

Indonesia has the potential huge vegetable in the production of organic insecticide. In many areas still needed assistance to the farmer groups to produce and use organic insecticide. The objective of this study was to determine the effectiveness of assistance in the production and use of organic insecticides in Farmers Group Sumber Urip Malang. The design study is cross sectional. Assistance performed 10 times in the production and use of organic insecticides involving 10 Farmers Group Sumber Urip I and 10 Farmers Group Sumber Urip II. Before the assistance do is the pretest and after the assistance do is posttest to knowing the knowledge and skills in the production and use of organic insecticides. Data collection method used was a questionnaire, observation, and interviews, while the method of data analysis used is the paired t-test. The results showed that; 1) there is a significant difference of knowledge production of organic insecticide before and after assistance (t-hit> t-tab0,01, 7.259 > 2.861), 2) there are significant differences of organic insecticide production skills before and after assistance (t-hit > t-tab0,01, 10.057 > 2.861), 3) there are significant differences knowledge of the use of organic insecticides before and after assistance (t-hit > t-tab0,01, 8.731 > 2.861), and 4) there are differences significant organic insecticide USAge skills before and after assistance (t-hit > t-tab0,01, 8.028 > 2.861). From the results of such research can be summed up the results of research that effective assistance to increase skills and knowledge production and use of organic insecticides

Exclusion criteria for systematic reviews and meta-analyses of pandemic influenza interventions.

<p>Exclusion criteria for systematic reviews and meta-analyses of pandemic influenza interventions.</p

Systematic review flow diagram.

<p>Systematic review flow diagram.</p

Summary of reviews included in the systematic review of pandemic influenza interventions.

<p>Summary of reviews included in the systematic review of pandemic influenza interventions.</p

Assessing the State of Knowledge Regarding the Effectiveness of Interventions to Contain Pandemic Influenza Transmission: A Systematic Review and Narrative Synthesis

<div><p>Background</p><p>Influenza pandemics occur when a novel influenza strain, to which humans are immunologically naïve, emerges to cause infection and illness on a global scale. Differences in the viral properties of pandemic strains, relative to seasonal ones, can alter the effectiveness of interventions typically implemented to control seasonal influenza burden. As a result, annual control activities may not be sufficient to contain an influenza pandemic.</p><p>Purpose</p><p>This study seeks to inform pandemic policy and planning initiatives by reviewing the effectiveness of previous interventions to reduce pandemic influenza transmission and infection. Results will inform the planning and design of more focused in-depth systematic reviews for specific types of interventions, thus providing the most comprehensive and current understanding of the potential for alternative interventions to mitigate the burden of pandemic influenza.</p><p>Methods</p><p>A systematic review and narrative synthesis of existing systematic reviews and meta-analyses examining intervention effectiveness in containing pandemic influenza transmission was conducted using information collected from five databases (PubMed, Medline, Cochrane, Embase, and Cinahl/EBSCO). Two independent reviewers conducted study screening and quality assessment, extracting data related to intervention impact and effectiveness.</p><p>Results and Discussion</p><p>Most included reviews were of moderate to high quality. Although the degree of statistical heterogeneity precluded meta-analysis, the present systematic review examines the wide variety of interventions that can impact influenza transmission in different ways. While it appears that pandemic influenza vaccination provides significant protection against infection, there was insufficient evidence to conclude that antiviral prophylaxis, seasonal influenza cross-protection, or a range of non-pharmaceutical strategies would provide appreciable protection when implemented in isolation. It is likely that an optimal intervention strategy will employ a combination of interventions in a layered approach, though more research is needed to substantiate this proposition.</p><p>Trial Registration</p><p>PROSPERO 42016039803</p></div

Systematic review search strategy as executed in Medline.

<p>Systematic review search strategy as executed in Medline.</p

Thiazolidinedione drugs in the treatment of type 2 diabetes mellitus: past, present and future

<p>Thiazolidinedione (TZD) drugs used in the treatment of type 2 diabetes mellitus (T2DM) have proven effective in improving insulin sensitivity, hyperglycemia, and lipid metabolism. Though well tolerated by some patients, their mechanism of action as ligands of peroxisome proliferator-activated receptors (PPARs) results in the activation of several pathways in addition to those responsible for glycemic control and lipid homeostasis. These pathways, which include those related to inflammation, bone formation, and cell proliferation, may lead to adverse health outcomes. As treatment with TZDs has been associated with adverse hepatic, cardiovascular, osteological, and carcinogenic events in some studies, the role of TZDs in the treatment of T2DM continues to be debated. At the same time, new therapeutic roles for TZDs are being investigated, with new forms and isoforms currently in the pre-clinical phase for use in the prevention and treatment of some cancers, inflammatory diseases, and other conditions. The aims of this review are to provide an overview of the mechanism(s) of action of TZDs, a review of their safety for use in the treatment of T2DM, and a perspective on their current and future therapeutic roles.</p

Predicted number of deaths, and percentage of total mortality accounted for by each age group.

<p>Predicted number of deaths, and percentage of total mortality accounted for by each age group.</p

Daily acute-care hospital demand, charted as the percentage of all acute-care hospital beds in the Ottawa–Gatineau CMA, under seven key intervention scenarios.

<p>Daily acute-care hospital demand, charted as the percentage of all acute-care hospital beds in the Ottawa–Gatineau CMA, under seven key intervention scenarios.</p

Transmissibility function parameters.

<p>Transmissibility function parameters.</p