Undergraduate technical skills training guided by student tutors – Analysis of tutors' attitudes, tutees' acceptance and learning progress in an innovative teaching model-0

<p><b>Copyright information:</b></p><p>Taken from "Undergraduate technical skills training guided by student tutors – Analysis of tutors' attitudes, tutees' acceptance and learning progress in an innovative teaching model"</p><p>http://www.biomedcentral.com/1472-6920/8/18</p><p>BMC Medical Education 2008;8():18-18.</p><p>Published online 9 Apr 2008</p><p>PMCID:PMC2324090.</p><p></p

MOESM1 of MicroRNA expression profiling for the prediction of resistance to neoadjuvant radiochemotherapy in squamous cell carcinoma of the esophagus

Additional file 1. Target sequences of miRNAs

Proapoptotic activity of Ukrain is based on L. alkaloids and mediated via a mitochondrial death pathway-12

<p><b>Copyright information:</b></p><p>Taken from "Proapoptotic activity of Ukrain is based on L. alkaloids and mediated via a mitochondrial death pathway"</p><p>BMC Cancer 2006;6():14-14.</p><p>Published online 17 Jan 2006</p><p>PMCID:PMC1379651.</p><p>Copyright © 2006 Habermehl et al; licensee BioMed Central Ltd.</p> extract adjusted to the respective chelidonine concentration. Apoptosis induction was analysed by fluorescence microscopy upon combined staining with Hoechst33342 and propidium iodide. The percentage of cells with characteristic apoptotic nuclear morphology was determined by counting a minimum of 250 cells per data point in each of at least three independent experiments. Data represent the percentage of cells with apoptotic nuclear morphology (means ± SD, n = 3). . Jurkat Vector cells were treated for 24 h with medium supplemented with solvent or 50 μM extract adjusted to the respective chelidonine-concentration. Apoptosis induction was analysed by fluorescence microscopy upon combined staining with Hoechst33342 and propidium iodide. Characteristic micrographs of nuclear morphology are shown. . Jurkat vector cells were treated for 24 h with medium supplemented with solvent or 1, 5, 10 and 50 μM L. extract adjusted to the respective chelidonine-concentration. Induction of apoptosis was then measured using flow cytometry (cell shrinkage: white bars; breakdown of mitochondrial membrane potential: grey bars; caspase-activation: black bars). Data show means ± SD (n ≥ 3)

Proapoptotic activity of Ukrain is based on L. alkaloids and mediated via a mitochondrial death pathway-5

<p><b>Copyright information:</b></p><p>Taken from "Proapoptotic activity of Ukrain is based on L. alkaloids and mediated via a mitochondrial death pathway"</p><p>BMC Cancer 2006;6():14-14.</p><p>Published online 17 Jan 2006</p><p>PMCID:PMC1379651.</p><p>Copyright © 2006 Habermehl et al; licensee BioMed Central Ltd.</p>medium or 10 μg/ml Ukrain, for 12 h with medium or 25 μM Etoposide and for 48 h with medium or irradiated with 10 Gy 48 h prior to determination of apoptosis. Apoptosis was quantified by fluorescence microscopy upon Hoechst33342-staining by counting cells with apoptotic nuclear morphology. Data show specific apoptosis (apoptosis rates of treated cells minus apoptosis rates of untreated cells) as means ± SD (n = 3). One-way ANOVA was performed using GraphPad InStat version 3.00 for Windows 95, GraphPad Software, San Diego California USA, . . Jurkat Vector, Jurkat Bcl-2 as well as Jurkat Caspase-9 DN cells were treated for 24 h with medium or 5, 10 and 50 μg/ml Ukrain. Apoptosis induction was then quantified by determination of the mitochondrial membrane potential (Δψm) (right panel). Data show induction of specific apoptosis (means ± SD; n ≥ 3). One-way ANOVA was performed using GraphPad InStat version 3.00 for Windows 95, GraphPad Software, San Diego California USA, . . Expression of Bcl-2 in Jurkat Vector and Bcl-2 overexpressing Jurkat cells (Jurkat Bcl-2) (upper panel) as well as expression of caspase-9 in Jurkat Vector and Jurkat cells expressing a dominant negative caspase-9 (Jurkat Caspase-9 DN) (lower panel) were verified by Western blot analysis of cytotsolic extracts with the respective antibodies. Jurkat Vector cells, Jurkat Bcl-2 cells as well as Jurkat Caspase-9 DN cells were treated for 0, 6, 12 and 24 h with medium or 10 μg/ml Ukrain. Caspase-activation was then determined by Western blot analysis of cytosolic extracts with antibodies against full length and active caspase-3, caspase-8 as well as PARP and cleaved PARP. Data from one representative experiment are shown

Dose profile in the beam channel: Case 4, FS 4, 270°.

<p>Demonstration of the dose profile from the proximal to the distal part of the beam channel.</p

ratios, Target, OAR and Cumulative criteria.

<p> ratios, Target, OAR and Cumulative criteria.</p

Optimization Process: Case 5, FS 5.

<p>Optimization process consisting of up to 3 steps: target plan optimization and 2 forward calculations.</p

Proapoptotic activity of Ukrain is based on L. alkaloids and mediated via a mitochondrial death pathway-10

<p><b>Copyright information:</b></p><p>Taken from "Proapoptotic activity of Ukrain is based on L. alkaloids and mediated via a mitochondrial death pathway"</p><p>BMC Cancer 2006;6():14-14.</p><p>Published online 17 Jan 2006</p><p>PMCID:PMC1379651.</p><p>Copyright © 2006 Habermehl et al; licensee BioMed Central Ltd.</p>/z 348.4; : LC-MS/MS ion chromatogram of m/z 354.1; : LC-MS/MS ion chromatogram of m/z 370.2

FS Evaluation: Dose profile.

<p>FS Evaluation: Dose profile.</p

Index Evaluation.

<p>Comparison of the plans by the three indices. Target Criteria, OAR Criteria, and Cumulative Criteria.</p