435 research outputs found
Estimating Body Segment Orientation by Applying Inertial and Magnetic Sensing Near Ferromagnetic Materials
Inertial and magnetic sensors are very suitable for ambulatory monitoring of human posture and movements. However, ferromagnetic materials near the sensor disturb the local magnetic field and, therefore, the orientation estimation. A Kalman-based fusion algorithm was used to obtain dynamic orientations and to minimize the effect of magnetic disturbances. This paper compares the orientation output of the sensor fusion using three-dimensional inertial and magnetic sensors against a laboratory bound opto-kinetic system (Vicon) in a simulated work environment. With the tested methods, the difference between the optical reference system and the output of the algorithm was 2.6deg root mean square (rms) when no metal was near the sensor module. Near a large metal object instant errors up to 50deg were measured when no compensation was applied. Using a magnetic disturbance model, the error reduced significantly to 3.6deg rms
Compensation of Magnetic Disturbances Improves Inertial and Magnetic Sensing of Human Body Segment Orientation
This paper describes a complementary Kalman filter design to estimate orientation of human body segments by fusing gyroscope, accelerometer, and magnetometer signals from miniature sensors. Ferromagnetic materials or other magnetic fields near the sensor module disturb the local earth magnetic field and, therefore, the orientation estimation, which impedes many (ambulatory) applications. In the filter, the gyroscope bias error, orientation error, and magnetic disturbance error are estimated. The filter was tested under quasi-static and dynamic conditions with ferromagnetic materials close to the sensor module. The quasi-static experiments implied static positions and rotations around the three axes. In the dynamic experiments, three-dimensional rotations were performed near a metal tool case. The orientation estimated by the filter was compared with the orientation obtained with an optical reference system Vicon. Results show accurate and drift-free orientation estimates. The compensation results in a significant difference (p<0.01) between the orientation estimates with compensation of magnetic disturbances in comparison to no compensation or only gyroscopes. The average static error was 1.4/spl deg/ (standard deviation 0.4) in the magnetically disturbed experiments. The dynamic error was 2.6/spl deg/ root means square
Achieving Sustainability Through Geodata: An Empirical Study of Challenges and Barriers
Master's thesis in Information systems (IS501)Research within data management is often based on the elements of the data lifecycle. Organizations and businesses are also becoming more interested in data lifecycle management to leverage their data streams, compounded by an interest in geographical attributes within the data –referred to as geodata. Geodata provides a richer basis for analysis and is increasingly important within urban planning. Furthermore, the pressure to achieve sustainability goals calls for improving the data lifecycle. The challenge remainsas to what can be improvedwithin the data lifecycle –with geodata as an important input –to achieve sustainability dimensions. Our main contribution through this study is shedding light on challenges withgeodata from an Information Systems (IS) and sustainability perspective. Additionally, the identified challenges are also feedback to data management research and the data lifecycle
Interial sensing in a hand held dynamometer
Two methods for kinematic sensing in a hand-held dynamometer using accelerometers and gyroscopes are presented. The first method integrates the angular velocity signal from the gyroscope, after calibration of gyroscope offset and joint angle from a static period immediately preceding each measurement. The second method estimates tangential and radial accelerations, enabling the estimation of the gravity components in the accelerometer signals under dynamic conditions, and thus angle reconstruction. The second method appeared to perform best in preliminary test
Capacity Building in Earth Observation: from Outcomes to Impact and Sustainability : abstract + powerpoint
Spatial solutions play an increasingly important role in meeting many of humankind’s complex challenges, such as climate change, population growth, and related claims for sufficient and secure food, water, energy, health, land and housing provision. Earth observations and geospatial technology are rapidly changing society everywhere − mobile, sensor and internet revolutions are touching Africa and Asia equally forcefully. Entrepreneurship and innovation are new aspects in capacity development activities. Many capacity building efforts focus on individuals while sustainable impact requires focus on organizational change and supranational coordination. Over the past several decades, many regional centers have been established for capacity building in Earth observation in developing countries and emerging economies. ITC of the University of Twente is an international knowledge hub in geospatial sciences, with an emphasis on collaborative educational and research activities in geo-information science and Earth observation and participation of students from around the world. SERVIR is a partnership of NASA, USAID, and leading regional technical organizations that develops innovative geospatial solutions to improve livelihoods and foster self-reliance across a global network in Asia, Africa, and the Americas. In this presentation, ITC and SERVIR will provide examples of and lessons learned from our activities and networks to strengthen the capacity and use of Earth observations in the developing world
Fatty acid 16:4(n-3) stimulates a GPR120-induced signaling cascade in splenic macrophages to promote chemotherapy resistance
Although chemotherapy is designed to eradicate tumor cells, it also has significant effects on normal tissues. The platinum-induced fatty acid 16:4(n-3) (hexadeca-4,7,10,13-tetraenoic acid) induces systemic resistance to a broad range of DNA-damaging chemotherapeutics. We show that 16:4(n-3) exerts its effect by activating splenic F4/80+/CD11blow macrophages, which results in production of chemoprotective lysophosphatidylcholines (LPCs). Pharmacologic studies, together with analysis of expression patterns, identified GPR120 on F4/80+/CD11blow macrophages as the relevant receptor for 16:4(n-3). Studies that used splenocytes from GPR120-deficient mice have confirmed this conclusion. Activation of the 16:4(n-3)-GPR120 axis led to enhanced cPLA2 activity in these splenic macrophages and secretion of the resistance-inducing lipid mediator, lysophosphatidylcholine(24:1). These studies identify a novel and unexpected function for GPR120 and suggest that antagonists of this receptor might be effective agents to limit development of chemotherapy resistance.—Houthuijzen, J. M., Oosterom, I., Hudson, B. D., Hirasawa, A., Daenen, L. G. M., McLean, C. M., Hansen, S. V. F., van Jaarsveld, M. T. M., Peeper, D. S., Jafari Sadatmand, S., Roodhart, J. M. L., van de Lest, C. H. A., Ulven, T., Ishihara, K., Milligan, G., Voest, E. E. Fatty acid 16:4(n-3) stimulates a GPR120-induced signaling cascade in splenic macrophages to promote chemotherapy resistance
Conductance fluctuations in diffusive rings: Berry phase effects and criteria for adiabaticity
We study Berry phase effects on conductance properties of diffusive
mesoscopic conductors, which are caused by an electron spin moving through an
orientationally inhomogeneous magnetic field. Extending previous work, we start
with an exact, i.e. not assuming adiabaticity, calculation of the universal
conductance fluctuations in a diffusive ring within the weak localization
regime, based on a differential equation which we derive for the diffuson in
the presence of Zeeman coupling to a magnetic field texture. We calculate the
field strength required for adiabaticity and show that this strength is reduced
by the diffusive motion. We demonstrate that not only the phases but also the
amplitudes of the h/2e Aharonov-Bohm oscillations are strongly affected by the
Berry phase. In particular, we show that these amplitudes are completely
suppressed at certain magic tilt angles of the external fields, and thereby
provide a useful criterion for experimental searches. We also discuss Berry
phase-like effects resulting from spin-orbit interaction in diffusive
conductors and derive exact formulas for both magnetoconductance and
conductance fluctuations. We discuss the power spectra of the
magnetoconductance and the conductance fluctuations for inhomogeneous magnetic
fields and for spin-orbit interaction.Comment: 18 pages, 13 figures; minor revisions. To appear in Phys. Rev.
Bregman Voronoi Diagrams: Properties, Algorithms and Applications
The Voronoi diagram of a finite set of objects is a fundamental geometric
structure that subdivides the embedding space into regions, each region
consisting of the points that are closer to a given object than to the others.
We may define many variants of Voronoi diagrams depending on the class of
objects, the distance functions and the embedding space. In this paper, we
investigate a framework for defining and building Voronoi diagrams for a broad
class of distance functions called Bregman divergences. Bregman divergences
include not only the traditional (squared) Euclidean distance but also various
divergence measures based on entropic functions. Accordingly, Bregman Voronoi
diagrams allow to define information-theoretic Voronoi diagrams in statistical
parametric spaces based on the relative entropy of distributions. We define
several types of Bregman diagrams, establish correspondences between those
diagrams (using the Legendre transformation), and show how to compute them
efficiently. We also introduce extensions of these diagrams, e.g. k-order and
k-bag Bregman Voronoi diagrams, and introduce Bregman triangulations of a set
of points and their connexion with Bregman Voronoi diagrams. We show that these
triangulations capture many of the properties of the celebrated Delaunay
triangulation. Finally, we give some applications of Bregman Voronoi diagrams
which are of interest in the context of computational geometry and machine
learning.Comment: Extend the proceedings abstract of SODA 2007 (46 pages, 15 figures
Toward Reliable Uptake Metrics in Large Vessel Vasculitis Studies
The aim of this study is to investigate the influence of sex, age, fat mass, fasting blood glucose level (FBGL), and estimated glomerular filtration rate (eGFR) on blood pool activity in patients with large vessel vasculitis (LVV). Blood pool activity was measured in the superior caval vein using mean, maximum, and peak standardized uptake values corrected for body weight (SUVs) and lean body mass (SULs) in 41 fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) scans of LVV patients. Sex influence on the blood pool activity was assessed with t-tests, while linear correlation analyses were used for age, fat mass, FBGL, and eGFR. Significantly higher SUVs were found in women compared with men, whereas SULs were similar between sexes. In addition, higher fat mass was associated with increased SUVs (r = 0.56 to 0.65; all p p > 0.05). Lower eGFR was associated with a higher FDG blood pool activity for all uptake values. In FDG-PET/CT studies with LVV patients, we recommend using SUL over SUV, while caution is advised in interpreting SUV and SUL measures when patients have impaired kidney function
Correlation Functions for Diffusion-Limited Annihilation, A + A -> 0
The full hierarchy of multiple-point correlation functions for
diffusion-limited annihilation, A + A -> 0, is obtained analytically and
explicitly, following the method of intervals. In the long time asymptotic
limit, the correlation functions of annihilation are identical to those of
coalescence, A + A -> A, despite differences between the two models in other
statistical measures, such as the interparticle distribution function
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