281 research outputs found

    How Can the European Federation for Colposcopy Promote High Quality Colposcopy Throughout Europe?

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    Since its inception in 1998, the European Federation for Colposcopy (EFC) now comprises 26 member societies. Its principle aim is to promote high quality colposcopy throughout Europe with special emphasis on training, education and treatment. This review summarises EFC’s activities and achievements to date

    Supplemental Data Set 1

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    Differentially expressed genes between wild type and gif1-1 mutant

    Supplemental Data Set 2

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    Putative GIF1 target genes (GIF1 high-confidence peak within 10kb)

    Controlling the Assembly of Nanoparticle Mixtures With Two Orthogonal Polymer Complexation Reactions

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    Self-assembly from mixed dispersions of three sizes of monodisperse polystyrene nanoparticles, large (L), medium (M), and small (S), was controlled by coating each particle type with either a monofunctional or bifunctional polymer capable of participating in specific complexation reactions. The complexation reactions were (1) complexation between phenolic polymers and polyethylene glycol (PEG) containing polymers and (2) condensation of phenylboronic acid containing polymers with polyols. These complexation reactions function independently and can be “turned off” independently; phenylboronic acid complexation was reversed by lowering the pH, whereas the interactions of phenolic copolymers with PEG copolymers could be reversed by adding excess PEG homopolymer. The specificity and reversibility of the interactions was demonstrated by the formation of simple binary aggregates from mixtures. The bifunctional copolymers were poly­(vinyl phenol-<i>co</i>-diallyldimethyl ammonium chloride), Ph-DADMAC, and poly­(3-acrylamide phenylboronic acid-<i>co</i>-PEG methacrylate), PBA-PEG. The monofunctional polymer was polyvinylalcohol, PVA. Ph-DADMAC forms complexes with PBA-PEG (H-bonding) and with anionic surfaces or polymers (electrostatic/polyelectrolyte complexation). PBA-PEG complexes with Ph-DADMAC (H-bonding) and with PVA (boronate ester formation). PVA does not interact with Ph-DADMAC; therefore, PVA coated particles do not deposit onto Ph-DADMAC coated particles

    Emotional Experience during Human-Computer Interaction: A Survey

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    As human-computer interaction (HCI) technology becomes more and more integrated into our daily life, increasing attention has been drawn towards the interaction experience in addition to HCI efficiency. In the present study, we conducted a survey to explore context-specific emotional experience in HCI. Four hundred participants were recruited to report the frequency of their emotional experiences on 44 fine-grained emotion items in six representative HCI scenarios. Compared with six matched human-human interaction (HHI) scenarios used as control, the HCI scenarios were in general more frequently associated with negative emotions, and less frequently associated with positive emotions, especially when computer served as a tool for communication with other people. Furthermore, the 44 emotional experience items in HCI were summarized as five factors, representing low-arousal focused, positively engaged, emotionally empathetic, high-arousal negative and frustratingly confused. Our study presents a comprehensive overview of context-specific emotional experience in human-computer interactions and provides a framework for emotion evaluation in HCI applications.</p

    Framework for Evaluation of Navigation Risk.

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    <p>Framework for Evaluation of Navigation Risk.</p

    Use of Cusp Catastrophe for Risk Analysis of Navigational Environment: A Case Study of Three Gorges Reservoir Area

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    <div><p>A water traffic system is a huge, nonlinear, complex system, and its stability is affected by various factors. Water traffic accidents can be considered to be a kind of mutation of a water traffic system caused by the coupling of multiple navigational environment factors. In this study, the catastrophe theory, principal component analysis (PCA), and multivariate statistics are integrated to establish a situation recognition model for a navigational environment with the aim of performing a quantitative analysis of the situation of this environment via the extraction and classification of its key influencing factors; in this model, the natural environment and traffic environment are considered to be two control variables. The Three Gorges Reservoir area of the Yangtze River is considered as an example, and six critical factors, i.e., the visibility, wind, current velocity, route intersection, channel dimension, and traffic flow, are classified into two principal components: the natural environment and traffic environment. These two components are assumed to have the greatest influence on the navigation risk. Then, the cusp catastrophe model is employed to identify the safety situation of the regional navigational environment in the Three Gorges Reservoir area. The simulation results indicate that the situation of the navigational environment of this area is gradually worsening from downstream to upstream.</p></div

    Image_1_Tinnitus-associated cognitive and psychological impairments: a comprehensive review meta-analysis.JPEG

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    BackgroundTinnitus is strongly associated with an increased risk of cognitive disabilities. The findings of this research will provide valuable support for future investigations aimed at determining the correlation between tinnitus and the risk of cognitive impairments.ObjectivesWe investigated the potential correlation between tinnitus and the risk of various cognitive impairments, such as dementia, compromised learning attention, anxiety, depression, and insomnia. The study examined this relationship collectively and by categorizing the data based on different age groups.MethodsWe compiled data from case–control studies and cohort studies obtained from reputable databases such as PubMed, Cochrane Library, and Embase. To minimize potential bias, two reviewers independently assessed the selected articles. After extracting the data, we calculated the pooled odds ratios (ORs) using a random-effects model.ResultsSeventeen relevant studies, comprising an adult population, were included in this analysis. Pooled estimated outcomes revealed a strong association between tinnitus and an elevated risk of dementia-compromised learning, auditory attention, anxiety, depression, and poor sleep quality (PConclusionTinnitus has the potential to increase the risk of cognitive impairments. Moreover, geriatric patients aged above 60 shows a higher susceptibility to developing cognitive disabilities compared to their younger counterparts.</p
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