The influence of cyclophosphamide on the growth of <i>D</i>. <i>magna</i>.

<p>(a) Average ± SD growth rate of <i>Daphnia</i> clones D, N and e S on Day 5, cultured with (grey bars) or without (white bars) cyclophosphamide.</p

The influence of cyclophosphamide on the reproduction of <i>D</i>. <i>magna</i>.

<p>Average (± SD) (a) age, (b) size at first reproduction and (c) first neonate number of <i>Daphnia</i> (Clones D, N and S) cultured with (grey bars) or without (white bars) cyclophosphamide. Stars indicate significant differences between the control and experimental groups.</p

The experimental design (description in the text).

<p>The experimental design (description in the text).</p

Proteins with changed expressions in the S clone individuals which had been treated with CP, compared to control individuals, with q-value < 0.1 (ratio = control/CP treated animals).

<p>Proteins with changed expressions in the S clone individuals which had been treated with CP, compared to control individuals, with q-value < 0.1 (ratio = control/CP treated animals).</p

Proteins with changed expressions in the D clone individuals which had been treated with CP, compared to control individuals, with q-value < 0.1 (ratio = control (C)/CP treated animals).

<p>Proteins with changed expressions in the D clone individuals which had been treated with CP, compared to control individuals, with q-value < 0.1 (ratio = control (C)/CP treated animals).</p

Common proteins with changed levels in <i>Daphnia</i> animals treated with cyclophosphamide.

<p>A Venn diagram showing common proteins, either (a) up- or (b) down regulated, in <i>Daphnia</i>, which changed significantly (q value < 0.1) in the clone D, N and S individuals which had been treated with cyclophosphamide.</p

The influence of cyclophosphamide on the growth of <i>D</i>. <i>magna</i>.

<p>(a) Average ± SD growth rate of <i>Daphnia</i> clones D, N and e S on Day 5, cultured with (grey bars) or without (white bars) cyclophosphamide.</p

Proteins with changed expressions in the N clone individuals which had been treated with CP, compared to control individuals, with q-value < 0.1 (ratio = control/CP treated animals).

<p>Proteins with changed expressions in the N clone individuals which had been treated with CP, compared to control individuals, with q-value < 0.1 (ratio = control/CP treated animals).</p