Impacts of the COVID-19 pandemic on reporting of rape, serious sexual offences, and domestic abuse in one English police force

Research suggests that during the COVID-19 pandemic reports of rapes and serious sexual offences to the authorities have declined while calls to domestic violence helplines have soared. This article focuses on the impacts of the COVID-19 outbreak on reporting to the police in cases of rape, serious sexual offences and domestic abuse in one police force in England. Data from the force’s crime reporting system was provided from 2018 to 2021, including over 10,000 reports of rapes and serious sexual offences and over 5,000 reports of domestic abuse. An Interrupted Time Series analysis was used to evaluate the impact of lockdown on reporting rates, with segmented regression to measure the changes in reporting before and after the start of the pandemic in March 2020. This article is the first of its kind to explore the impact of COVID-19 on sexual and domestic violence at more than an aggregate level, demonstrating how COVID-19 has had a variable impact on different groups of victims, and how stay at home orders specifically have impacted on reporting rates. These data provide novel and valuable insights into the effects of the COVID-19 pandemic on the reporting of sexual violence and domestic abuse

Independent sexual violence advisers (ISVAs) in England, Wales and Northern Ireland: a study of impacts, effects, coping mechanisms and effective support systems for people working as ISVAs and ISVA Managers

This study is the first of its kind in England, Wales and Northern Ireland and was carried out to gather information about the impact of working as Independent Sexual Violence Advisers (ISVAs) or ISVA Managers. The ISVA role is relatively new, and as such, little is known about this difficult and emotionally charged work. Although some literature looks at the impact of working in the sexual violence field, there is little from England, Wales or Northern Ireland, and even less focused on the direct, ongoing, face-to-face work ISVAs do. This report focuses on the impacts, effects, coping mechanisms and effective support systems for people working as ISVAs and ISVA Managers in supporting victim-survivors of sexual violence across England, Wales and Northern Ireland. Since its introduction in 2005, the ISVA role has been invaluable in providing continuous support to victim-survivors of sexual violence and working to meet their emotional and practical needs during the criminal justice process. As conviction rates are at an all-time low, ISVAs can also provide support to people who may otherwise feel let down by the Criminal Justice System. ISVAs can also support people who do not want to report the crime to the police – helping people at, potentially, the lowest point of their life. This survey focused on providing an overview of the ISVA role (e.g. context they work in, caseloads, supervision and support available) and determining which factors predict the likelihood of experiencing negative and positive impacts as a result of the work they do

Non-Universal Critical Behaviour of Two-Dimensional Ising Systems

Two conditions are derived for Ising models to show non-universal critical behaviour, namely conditions concerning 1) logarithmic singularity of the specific heat and 2) degeneracy of the ground state. These conditions are satisfied with the eight-vertex model, the Ashkin-Teller model, some Ising models with short- or long-range interactions and even Ising systems without the translational or the rotational invariance.Comment: 17 page

Radio Galaxy Clustering at z~0.3

Radio galaxies are uniquely useful as probes of large-scale structure as their uniform identification with giant elliptical galaxies out to high redshift means that the evolution of their bias factor can be predicted. As the initial stage in a project to study large-scale structure with radio galaxies we have performed a small redshift survey, selecting 29 radio galaxies in the range 0.19<z<0.45 from a contiguous 40 square degree area of sky. We detect significant clustering within this sample. The amplitude of the two-point correlation function we measure is consistent with no evolution from the local (z<0.1) value. This is as expected in a model in which radio galaxy hosts form at high redshift and thereafter obey a continuity equation, although the signal:noise of the detection is too low to rule out other models. Larger surveys out to z~1 should reveal the structures of superclusters at intermediate redshifts and strongly constrain models for the evolution of large-scale structure.Comment: 7 pages, 3 figures, accepted by ApJ Letter

Theory of Pseudomodes in Quantum Optical Processes

This paper deals with non-Markovian behaviour in atomic systems coupled to a structured reservoir of quantum EM field modes, with particular relevance to atoms interacting with the field in high Q cavities or photonic band gap materials. In cases such as the former, we show that the pseudo mode theory for single quantum reservoir excitations can be obtained by applying the Fano diagonalisation method to a system in which the atomic transitions are coupled to a discrete set of (cavity) quasimodes, which in turn are coupled to a continuum set of (external) quasimodes with slowly varying coupling constants and continuum mode density. Each pseudomode can be identified with a discrete quasimode, which gives structure to the actual reservoir of true modes via the expressions for the equivalent atom-true mode coupling constants. The quasimode theory enables cases of multiple excitation of the reservoir to now be treated via Markovian master equations for the atom-discrete quasimode system. Applications of the theory to one, two and many discrete quasimodes are made. For a simple photonic band gap model, where the reservoir structure is associated with the true mode density rather than the coupling constants, the single quantum excitation case appears to be equivalent to a case with two discrete quasimodes

The Processing Pathway of Prelamin A

The conversion of mammalian prelamin A to mature lamin A proceeds through the removal of 18 amino acids from the carboxyl terminus. The initial step in this processing is the isoprenylation of a CAAX box cysteine. This proteolytic event is distinctive for prelamin A among the known prenylated mammalian proteins. Since the carboxyl terminus of prelamin A is removed during maturation, it is not obvious that this protein would undergo the two reactions subsequent to prenylation observed in other CAAX box proteins-the endoproteolytic removal of the carboxyl-terminal 3 amino acids and the subsequent methylation of the now carboxyl-terminal cysteine. To characterize the maturation of prelamin A further, we have developed a CHO-K1 cell line that possesses a dexamethasone-inducible human prelamin A against a genetic background of high mevalonate uptake. Utilizing this cell line in association with antibodies specific to the transgenic prelamin A, we have been able to demonstrate directly in vivo that prelamin A undergoes farnesylation and carboxymethylation prior to conversion to lamin A, as is the case for other prenylated proteins. We have demonstrated previously that in the absence of isoprenylation, conversion of prelamin A to lamin A is blocked, but that unprocessed prelamin A is transported to the nucleus where it can still undergo maturation. Consistent with the implications of these prior studies, we now demonstrate the presence of both subunits of farnesyl-protein transferase in the nucleus

Experimental feedback control of quantum systems using weak measurements

A goal of the emerging field of quantum control is to develop methods for quantum technologies to function robustly in the presence of noise. Central issues are the fundamental limitations on the available information about quantum systems and the disturbance they suffer in the process of measurement. In the context of a simple quantum control scenario--the stabilization of non-orthogonal states of a qubit against dephasing--we experimentally explore the use of weak measurements in feedback control. We find that, despite the intrinsic difficultly of implementing them, weak measurements allow us to control the qubit better in practice than is even theoretically possible without them. Our work shows that these more general quantum measurements can play an important role for feedback control of quantum systems.Comment: 4 pages, 3 figures. v2 Added extra citation, journal reference and DOI. Minor typographic correction

Differential neuroproteomic and systems biology analysis of spinal cord injury

Acute spinal cord injury (SCI) is a devastating condition with many consequences and no known effective treatment. Although it is quite easy to diagnose traumatic SCI, the assessment of injury severity and projection of disease progression or recovery are often challenging, as no consensus biomarkers have been clearly identified. Here rats were subjected to experimental moderate or severe thoracic SCI. At 24h and 7d postinjury, spinal cord segment caudal to injury center versus sham samples was harvested and subjected to differential proteomic analysis. Cationic/anionic-exchange chromatography, followed by 1D polyacrylamide gel electrophoresis, was used to reduce protein complexity. A reverse phase liquid chromatography-tandem mass spectrometry proteomic platform was then utilized to identify proteome changes associated with SCI. Twenty-two and 22 proteins were up-regulated at 24 h and 7 day after SCI, respectively; whereas 19 and 16 proteins are down-regulated at 24 h and 7 day after SCI, respectively, when compared with sham control. A subset of 12 proteins were identified as candidate SCI biomarkers - TF (Transferrin), FASN (Fatty acid synthase), NME1 (Nucleoside diphosphate kinase 1), STMN1 (Stathmin 1), EEF2 (Eukaryotic translation elongation factor 2), CTSD (Cathepsin D), ANXA1 (Annexin A1), ANXA2 (Annexin A2), PGM1 (Phosphoglucomutase 1), PEA15 (Phosphoprotein enriched in astrocytes 15), GOT2 (Glutamic-oxaloacetic transaminase 2), and TPI-1 (Triosephosphate isomerase 1), data are available via ProteomeXchange with identifier PXD003473. In addition, Transferrin, Cathepsin D, and TPI-1 and PEA15 were further verified in rat spinal cord tissue and/or CSF samples after SCI and in human CSF samples from moderate/severe SCI patients. Lastly, a systems biology approach was utilized to determine the critical biochemical pathways and interactome in the pathogenesis of SCI. Thus, SCI candidate biomarkers identified can be used to correlate with disease progression or to identify potential SCI therapeutic targets

Weak charge form factor and radius of 208Pb through parity violation in electron scattering

We use distorted wave electron scattering calculations to extract the weak charge form factor F_W(q), the weak charge radius R_W, and the point neutron radius R_n, of 208Pb from the PREX parity violating asymmetry measurement. The form factor is the Fourier transform of the weak charge density at the average momentum transfer q=0.475 fm$^{-1}$. We find F_W(q) =0.204 \pm 0.028 (exp) \pm 0.001 (model). We use the Helm model to infer the weak radius from F_W(q). We find R_W= 5.826 \pm 0.181 (exp) \pm 0.027 (model) fm. Here the exp error includes PREX statistical and systematic errors, while the model error describes the uncertainty in R_W from uncertainties in the surface thickness \sigma of the weak charge density. The weak radius is larger than the charge radius, implying a "weak charge skin" where the surface region is relatively enriched in weak charges compared to (electromagnetic) charges. We extract the point neutron radius R_n=5.751 \pm 0.175 (exp) \pm 0.026 (model) \pm 0.005 (strange) fm$, from R_W. Here there is only a very small error (strange) from possible strange quark contributions. We find R_n to be slightly smaller than R_W because of the nucleon's size. Finally, we find a neutron skin thickness of R_n-R_p=0.302\pm 0.175 (exp) \pm 0.026 (model) \pm 0.005 (strange) fm, where R_p is the point proton radius.Comment: 5 pages, 1 figure, published in Phys Rev. C. Only one change in this version: we have added one author, also to metadat

Non-Markovian Decay of a Three Level Cascade Atom in a Structured Reservoir

We present a formalism that enables the study of the non-Markovian dynamics of a three-level ladder system in a single structured reservoir. The three-level system is strongly coupled to a bath of reservoir modes and two quantum excitations of the reservoir are expected. We show that the dynamics only depends on reservoir structure functions, which are products of the mode density with the coupling constant squared. This result may enable pseudomode theory to treat multiple excitations of a structured reservoir. The treatment uses Laplace transforms and an elimination of variables to obtain a formal solution. This can be evaluated numerically (with the help of a numerical inverse Laplace transform) and an example is given. We also compare this result with the case where the two transitions are coupled to two separate structured reservoirs (where the example case is also analytically solvable)