Electrically-Small Low Q Radiator Structure and Method of Producing EM Waves Therewith

An electrically small radiator structure for radiating electromagnetic waves having an electrical size, k*a, with a value less than π/2 and above π/20,000 and configured to have at least a first and second magnetic, or electric, dipole element. Dipole elements are preferably oriented such that a source-associated standing energy value for the structure, or Wds(tR), is low, Radiative Q value preferably less than ⅓(k*a)3; and each of the elements, whether paired with respective electric dipole elements, is in electrical communication through a feed circuit to at least one power source. Further, a first dipole pair (or element) oriented orthogonally with respect to a second pair (or element) are in voltage phase-quadrature; the structure is operational at a frequency below 5 GHz; and dipole moments oriented such that the following is generally satisfied: a divergence of the Poynting vector of the pairs with respect to retarded time, namely ∇|t R ·N, has a value less than 1.0. Also, a method of producing electromagnetic waves using an electrically small radiator structure, including configuring the structure to have at least a first and second pair of dipole moments and an electrical size, k*a, with a value less than π/2 and above π/20,000; and powering a first feed area of the first pair and a second feed area of the second pair with at least one source operating at a frequency to radiate the waves

The Social-Safety System: Fortifying Relationships in the Face of the Unforeseeable

A model of the social-safety system is proposed to explain how people sustain a sense of safety in the relational world when they are not able to foresee the behavior of others. In this model, people can escape the acute anxiety posed by agents in their personal relational world behaving unexpectedly (e.g., spouse, child) by defensively imposing well-intentioned motivations on the agents controlling their sociopolitical relational world (e.g., President, Congress). Conversely, people can escape the acute anxiety posed by sociopolitical agents behaving unexpectedly by defensively imposing well-intentioned motivations on the agents controlling their personal relational world. Two daily diary studies, a longitudinal study of the 2018 midterm election, and a 3-year longitudinal study of newlyweds supported the hypotheses. On a daily basis, people who were less certain they could trust their romantic partner defended against acutely unforeseeable behavior in one relational world by affirming faith in the well-intentioned motivations of agents in the alternate world. Moreover, when people were more in the personal daily habit of finding safety in the alternate relational world in the face of the unexpected, those who were initially uncertain they could trust their romantic partner later evidenced greater comfort depending on their personal relationship partners

The Double-peaked Radio Light Curve of Supernova PTF11qcj

We present continued radio and X-ray follow-up observations of PTF11qcj, a highly energetic broad-lined Type Ic supernova (SN), with a radio peak luminosity comparable to that of the γ-ray burst (GRB) associated SN 1998bw. The latest radio observations, carried out with the Karl G. Jansky Very Large Array, extend up to ~5 yr after the PTF11qcj optical discovery. The radio light curve shows a double-peak profile, possibly associated with density variations in the circumstellar medium (CSM), or with the presence of an off-axis GRB jet. Optical spectra of PTF11qcj taken during both peaks of the radio light curve do not show the broad Hα features typically expected from H-rich circumstellar interaction. Modeling of the second radio peak within the CSM-interaction scenario requires a flatter density profile and an enhanced progenitor mass-loss rate compared to those required to model the first peak. Our radio data alone cannot rule out the alternative scenario of an off-axis GRB powering the second radio peak, but the derived GRB parameters are somewhat unusual compared to typical values found for cosmological long GRBs. On the other hand, Chandra X-ray observations carried out during the second radio peak are compatible with the off-axis GRB hypothesis, within the large measurement errors. We conclude that VLBI measurements of the PTF11qcj radio ejecta are needed to unambiguously confirm or rule out the off-axis GRB jet scenario

Psychosocial aspects of feeding children with neurodisability

The psychosocial support needs of parents considering a gastrostomy feeding tube for their disabled child are often overlooked, yet there is a growing body of evidence that attests to the decisional conflicts parents, often mothers, experience. This may be in addition to the stress associated with feeding a disabled child. The support needs of families and caregivers should be assessed, including the values parents attach to oral and tube feeding. Structured support should be embedded within the care pathway and both professionals, and service users, with appropriate training should be identified to ensure parental information needs, and any emotional, practical and financial issues are addressed

GLI1 regulates a novel neuropilin-2/alpha6beta1 integrin based autocrine pathway that contributes to breast cancer initiation

The characterization of cells with tumour initiating potential is significant for advancing our understanding of cancer and improving therapy. Aggressive, triple-negative breast cancers (TNBCs) are enriched for tumour-initiating cells (TICs). We investigated that hypothesis that VEGF receptors expressed on TNBC cells mediate autocrine signalling that contributes to tumour initiation. We discovered the VEGF receptor neuropilin-2 (NRP2) is expressed preferentially on TICs, involved in the genesis of TNBCs and necessary for tumour initiation. The mechanism by which NRP2 signalling promotes tumour initiation involves stimulation of the alpha6beta1 integrin, focal adhesion kinase-mediated activation of Ras/MEK signalling and consequent expression of the Hedgehog effector GLI1. GLI1 also induces BMI-1, a key stem cell factor, and it enhances NRP2 expression and the function of alpha6beta1, establishing an autocrine loop. NRP2 can be targeted in vivo to retard tumour initiation. These findings reveal a novel autocrine pathway involving VEGF/NRP2, alpha6beta1 and GLI1 that contributes to the initiation of TNBC. They also support the feasibility of NRP2-based therapy for the treatment of TNBC that targets and impedes the function of TICs. of EMBO

In-Space Assembly Capability Assessment for Potential Human Exploration and Science Applications

Human missions to Mars present several major challenges that must be overcome, including delivering multiple large mass and volume elements, keeping the crew safe and productive, meeting cost constraints, and ensuring a sustainable campaign. Traditional methods for executing human Mars missions minimize or eliminate in-space assembly, which provides a narrow range of options for addressing these challenges and limits the types of missions that can be performed. This paper discusses recent work to evaluate how the inclusion of in-space assembly in space mission architectural concepts could provide novel solutions to address these challenges by increasing operational flexibility, robustness, risk reduction, crew health and safety, and sustainability. A hierarchical framework is presented to characterize assembly strategies, assembly tasks, and the required capabilities to assemble mission systems in space. The framework is used to identify general mission system design considerations and assembly system characteristics by assembly strategy. These general approaches are then applied to identify potential in-space assembly applications to address each challenge. Through this process, several focus areas were identified where applications of in-space assembly could affect multiple challenges. Each focus area was developed to identify functions, potential assembly solutions and operations, key architectural trades, and potential considerations and implications of implementation. This paper helps to identify key areas to investigate were potentially significant gains in addressing the challenges with human missions to Mars may be realized, and creates a foundation on which to further develop and analyze in-space assembly concepts and assembly-based architectures