2,956 research outputs found
Performance Based Plastic Design of Concentrically Braced Frame attuned with Indian Standard code and its Seismic Performance Evaluation
In the Performance Based Plastic design method, the failure is predetermined; making it famous throughout the world. But due to lack of proper guidelines and simple stepwise methodology, it is not quite popular in India. In this paper, stepwise design procedure of Performance Based Plastic Design of Concentrically Braced frame attuned with the Indian Standard code has been presented. The comparative seismic performance evaluation of a six storey concentrically braced frame designed using the displacement based Performance Based Plastic Design (PBPD) method and currently used force based Limit State Design (LSD) method has also been carried out by nonlinear static pushover analysis and time history analysis under three different ground motions. Results show that Performance Based Plastic Design method is superior to the current design in terms of displacement and acceleration response. Also total collapse of the frame is prevented in the PBPD frame
Novel R2R Manufacturable Photonic-Enhanced Thin Film Solar Cells; January 28, 2010 -- January 31, 2011
Final subcontract report for PV Incubator project 'Novel R2R Manufacturable Photonic-Enhanced Thin Film Solar Cells.' The goal of this program was to produce tandem Si cells using photonic bandgap enhancement technology developed at ISU and Lightwave Power that would have an NREL-verified efficiency of 7.5% on 0.25 cm{sup 2} area tandem junction cell on plastic substrates. This goal was met and exceeded within the timeframe and budget of the program. On smaller area cells, the efficiency was even higher, {approx}9.5% (not verified by NREL). Appropriate polymers were developed to fabricate photonic and plasmonic devices on stainless steel, Kapton and PEN substrates. A novel photonic-plasmon structure was developed which shows a promise of improving light absorption in thin film cells, a better light absorption than by any other scheme
On existence of traveling wave of an HBV infection dynamics model: A novel approach
In this work, a hepatitis B virus infection dynamics model is proposed
including the spatial dependence of viruses. The existence of traveling waves
for the proposed model is established through the application of the celebrated
Gersgorin theorem. The procedure followed to establish the existence of a
traveling wave solution is innovative and probably the first attempt of this
particular approach. The elasticity of basic reproduction number with respect
to some model parameters are also shown. Furthermore, the effects of spatial
diffusivity of the viruses on infection are studied, and it is noticed that due
to the diffusion, viruses spread rapidly throughout the liver
A model for reversible electroporation to deliver drugs into diseased tissues
Drug delivery through electroporation could be highly beneficial for the
treatment of different types of diseased tissues within the human body. In this
work, a mathematical model of reversible tissue electroporation is presented
for injecting drug into the diseased cells. The model emphasizes the tissue
boundary where the drug is injected as a point source. Drug loss from the
tissue boundaries through extracellular space is studied. Multiple pulses are
applied to deliver a sufficient amount of drug into the targeted cells. The set
of differential equations that model the physical circumstances are solved
numerically. This model obtains a mass transfer coefficient in terms of pore
fraction coefficient and drug permeability. It controls the drug transport from
extracellular to intracellular space. The drug penetration throughout the
tissue is captured for the application of different pulses. The boundary
effects on drug concentration are highlighted in this study. The advocated
model is able to perform homogeneous drug transport into the cells so that the
affected tissue is treated completely. This model can be applied to optimize
clinical experiments by avoiding the lengthy and costly in vivo and in vitro
experiments.Comment: 18 page
Magnification relations in gravitational lensing via multidimensional residue integrals
We investigate the so-called magnification relations of gravitational lensing
models. We show that multidimensional residue integrals provide a simple
explanation for the existence of these relations, and an effective method of
computation. We illustrate the method with several examples, thereby deriving
new magnification relations for galaxy lens models and microlensing (point mass
lensing).Comment: 16 pages, uses revtex4, submitted to Journal of Mathematical Physic
Quantitative nucleotide level analysis of regulation of translation in response to depolarization of cultured neural cells
Studies on regulation of gene expression have contributed substantially to understanding mechanisms for the long-term activity-dependent alterations in neural connectivity that are thought to mediate learning and memory. Most of these studies, however, have focused on the regulation of mRNA transcription. Here, we utilized high-throughput sequencing coupled with ribosome footprinting to globally characterize the regulation of translation in primary mixed neuronal-glial cultures in response to sustained depolarization. We identified substantial and complex regulation of translation, with many transcripts demonstrating changes in ribosomal occupancy independent of transcriptional changes. We also examined sequence-based mechanisms that might regulate changes in translation in response to depolarization. We found that these are partially mediated by features in the mRNA sequence—notably upstream open reading frames and secondary structure in the 5′ untranslated region—both of which predict downregulation in response to depolarization. Translationally regulated transcripts are also more likely to be targets of FMRP and include genes implicated in autism in humans. Our findings support the idea that control of mRNA translation plays an important role in response to neural activity across the genome
A New Survey for Giant Arcs
We report on the first results of an imaging survey to detect strong
gravitational lensing targeting the richest clusters selected from the
photometric data of the Sloan Digital Sky Survey (SDSS) with follow-up deep
imaging observations from the Wisconsin Indiana Yale NOAO (WIYN) 3.5m telescope
and the University of Hawaii 88-inch telescope (UH88). The clusters are
selected from an area of 8000 deg^2 using the Red Cluster Sequence technique
and span the redshift range 0.1 < z < 0.6, corresponding to a comoving
cosmological volume of ~ 2 Gpc^3. Our imaging survey thus targets a volume more
than an order of magnitude larger than any previous search. A total of 240
clusters were imaged of which 141 had sub-arcsecond image quality. Our survey
has uncovered16 new lensing clusters with definite giant arcs, an additional 12
systems for which the lensing interpretation is very likely, and 9 possible
lenses which contain shorter arclets or candidate arcs which are less certain
and will require further observations to confirm their lensing origin. The
number of new cluster lenses detected in this survey is likely > 30. Among
these new systems are several of the most dramatic examples of strong
gravitational lensing ever discovered with multiple bright arcs at large
angular separation. These will likely become 'poster-child' gravitational
lenses similar to Abell 1689 and CL0024+1654. The new lenses discovered in this
survey will enable future sysetmatic studies of the statistics of strong
lensing and its implications for cosmology and our structure formation
paradigm.Comment: 19 pages, 7 pages of Figures, submitted to AJ. Fixed Typo
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