Exclusão do Crédito Tributário

 Cada vez mais, a sociedade, na luta pelos seus direitos, procura da melhor forma possível buscar a aplicação do mesmo quando se enconta diante de determinadas situações. Ora, dentro do Direito tributário, o indíviduo, pode requerer a isenção ou até mesmo anistia para circustâncias que se encontram presentes. Certamente, tais institutos somente são aplicados quando acompanhados pelos requisitos exigídos pela lei. Logo, o presente trabalho possui como objetivo apontar a importância de tais modalidades, uma vez que, nem todos possuem o conhecimento destes direitos

LIBERDADE DE EXPRESSÃO E O USO DAS REDES SOCIAIS QUAL O LIMITE DA SUA LIBERDADE?

O presente trabalho pretendeu analisar como o uso excessivo das mídias sociais acarreta em consequências estudantis e profissionais com acadêmicos da graduação de Direito, com ênfase nos futuros juristas

Functional impairments in white matter syndrome of neuropsychiatric systemic lupus erythematosus are similar to those observed in patients with multiple sclerosis

OBJECTIVE: In order to compare white matter syndrome of neuropsychiatric systemic lupus erythematosus (NPSLE) and multiple sclerosis (MS), an assessment on demographic, medical history, and clinical data was proposed. METHODS: Sixty-four patients with NPSLE and 178 with MS answered a questionnaire and were evaluated regarding functional system, expanded disability status scale (EDSS), Beck depression inventory (BDI), and Beck anxiety inventory (BAI). RESULTS: The prevalence of autoimmune diseases and altered consciousness was similar in both groups, however it was higher than in the general population. Systemic signs and symptoms occurred from 2.9 to 61.9% of the MS cases, while neurological signs and symptoms occurred in 9.4 to 76.4% of the NPSLE ones. The motor, visual, and mental systems were the most affected in both diseases. The BDI in NPSLE had higher scores and the BAI in MS. CONCLUSIONS: The functional impairments in NPSLE were similar to those of MS, although greater impairment of the functional systems of cerebellar, sensitivity, and sphincters occurred in MS cases, and greater symptoms of depression, anxiety, and headache also occurred in it

HÉRNIA DE SPIEGEL À ESQUERDA: DESCRIÇÃO DE CASO CLÍNICO E ANÁLISE DA LITERATURA

: As hérnias de Spiegel (HS) apresentam-se como um defeito raro da parede abdominal, correspondendo a 1-2% das hérnias da parede abdominal anterior. O diagnóstico pode ser particularmente difícil pelo quadro clínico vago. Normalmente têm indicação cirúrgica pelo risco de encarceramento e estrangulamento. Este artigo busca descrever o caso cínico de uma hérnia de Spiegel e analisar a abordagem da literatura sobre essa patologia

Assessing physical habitat structure and biological condition in eastern Amazonia stream sites

The advance of agricultural frontiers and industrialization in Amazonia has increased natural resource deterioration, resulting in degraded physical habitat structure and reduced local aquatic biodiversity. We evaluated the relative sensitivities of the Biological Monitoring Working Party (BMWP) and Average Score Per Taxon (ASPT) biotic indexes based on EPT (Ephemeroptera, Plecoptera, Trichoptera) versus EPT taxa richness, EPT abundance, and Shannon-Wiener EPT diversity for evaluating anthropogenic impacts on Amazonian streams. We expected that EPT-BMWP and EPT-ASPT would be more sensitive in detecting environmental changes on stream biota than the other measures. We sampled 32 stream sites in eastern Amazonia distributed along an environmental gradient resulting from different land use intensities. All the biological metrics except EPT-ASPT were significantly responsive to anthropogenic pressures; however, EPT taxa richness was slightly more responsive

Fluorescence properties of curcumin-loaded nanoparticles for cell tracking

Background: Posttransplant cell tracking, via stem cell labeling, is a crucial strategy for monitoring and maximizing benefits of cell-based therapies. The structures and functionalities of polysaccharides, proteins, and lipids allow their utilization in nanotechnology systems. Materials and methods: In the present study, we analyzed the potential benefit of curcumin-loaded nanoparticles (NPC) using Vero cells (in vitro) and NPC-labeled adipose-derived mesenchymal stem cells (NPC-ADMSCs) (in vivo) in myocardial infarction and sciatic nerve crush preclinical models. Thereafter, transplantation, histological examination, real time imaging, and assessment of tissue regeneration were done. Results: Transplanted NPC-ADMSCs were clearly identified and revealed potential benefit when used in cell tracking. Conclusion: This approach may have broad applications in modeling labeled transplanted cells and in developing improved stem cell therapeutic strategies.Fil: Mogharbel, Bassam Felipe. Pelé Pequeno Príncipe Institute; BrasilFil: Francisco, Julio Cesar. Pelé Pequeno Príncipe Institute; BrasilFil: Irioda, Ana Carolina. Pelé Pequeno Príncipe Institute; BrasilFil: Dziedzic, Dilcele Silva Moreira. Pelé Pequeno Príncipe Institute; BrasilFil: Ferreira, Priscila Elias. Pelé Pequeno Príncipe Institute; BrasilFil: de Souza, Daiany. Pelé Pequeno Príncipe Institute; BrasilFil: de Souza, Carolina Maria Costa Oliveira. Pelé Pequeno Príncipe Institute; BrasilFil: Neto, Nelson Bergonse. Pelé Pequeno Príncipe Institute; BrasilFil: Guarita Souza, Luiz Cesar. Universidade Federal do Paraná; BrasilFil: Franco, Celia Regina Cavichiolo. Universidade Federal do Paraná; BrasilFil: Nakamura, Celso Vataru. Universidade Estadual de Maringá; BrasilFil: Kaplum, Vanessa. Universidade Estadual de Maringá; BrasilFil: Mazzarino, Letícia. Universidade Federal de Santa Catarina; BrasilFil: Lemos Senna, Elenara. Universidade Federal de Santa Catarina; BrasilFil: Borsali, Redouan. Universite Grenoble Alpes; FranciaFil: Soto, Paula Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Físico-Química Biológicas; ArgentinaFil: Setton, Clara Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Físico-Química Biológicas; ArgentinaFil: Abdelwahid, Eltyeb. Northwestern University; Estados UnidosFil: Athayde Teixeira de Carvalho, Katherine. Pelé Pequeno Príncipe Institute; Brasi