The effect of platinum derivatives on both bacterial and human cells after application of platinum derivatives alone or encapsulated in liposomes.

<p>Relative change of growth rate of (A) <i>S</i>. <i>aureus</i> bacterial culture and (C) HFF after treatment with Pt-derivatives (100 μg/mL of Pt) during 24 h (bacterial culture) and 100 h (HFF) long experiments. (a) Cell culture without any treatment, (b) LipoCisPt, (c) CisPt, (d) LipoPtNPs and (e) PtNPs. Percentage survival of (B) <i>S</i>. <i>aureus</i> bacterial culture and (D) human foreskin fibroblasts (HFF) after 24 and 100 h of treatment with Pt-derivatives (100 μg/mL of Pt) alone and encapsulated in liposomes. For all measurement n = 3.</p

Selected haematological parameters of erythrocytes mixture with platelets and oxidative stress (GSH/GSSG) in the mixture after application of Pt derivatives encapsulated in liposomes or alone in concentrations 0, 12.5, 25, 50, 100 and 200 μg/mL of Pt and 0, 0.6, 1.3, 2.5, 5 and 10 mg/mL of liposomes.

<p>(A) Histograms of (a) erythrocytes and (b) platelets, and (c) visualisations of liposomes in the Baso channel after application of LipoCisPt, CisPt, LipoPtNPs and PtNPs. GSH/GSSG ratio of erythrocytes mixture with platelets in the same concentrations as in A—(B) LipoCisPt, (C) CisPt, (D) LipoPtNPs, and (E) PtNPs. (F) Mean of GSH/GSSG ratio. For all measurement n = 3, significant difference is indicated by *p<0.05.</p

Principles and Techniques for Sensor Data Fusion

This paper concerns a problem which is basic to perception: the integration of perceptual information into a coherent description of the world. In this paper we present perception as a process of dynamically maintaining a model of the local external environment. Fusion of perceptual information is at the heart of this process