2 research outputs found
SARS-CoV-2 seroprevalence study in Lambayeque, Peru. June–July 2020
Background: Estimating the cumulative prevalence of SARS-COV-2 will help to
understand the epidemic, contagion, and immunity to COVID-19 in vulnerable
populations. The objective is to determine the extent of infection in the general
population and the cumulative incidence by age group.
Methods: It was carried out with a longitudinal analytical study, in the population of
the Lambayeque region, located in the north of Peru. The selection was carried out in
multistages (districts, area, household, and finally choosing the interviewee within
the house). Seroprevalence was estimated as a positive result of the rapid test whether
it was positive IgM or positive IgG. An adjustment was made for the sampling
weights used.
Results: The seroprevalence found in the region was 29.5%. Young people between
21 and 50 years old presented the highest seroprevalence frequencies. A total of
25.4% were asymptomatic. The most frequent complaint was dysgeusia and
dysosmia (85.3% and 83.6%). Dysosmia (PR = 1.69), chest pain (PR = 1.49),
back pain (PR = 1.45), cough (PR = 1.44), fever (PR = 1.41), general malaise
(PR = 1.27) were associated factors with the higher the frequency of seropositivity for
SARS-CoV-2. Reporting of complete isolation at home decreased the frequency of
positivity (PR = 0.80), however, reporting having ARI contact (PR = 1.60), having
contact with a confirmed case (PR = 1.51), and going to market (PR = 1.26) increased
the frequency of positivity for SARS-CoV-2.
Conclusion: These results suggest that Lambayeque is the region with the highest
seroprevalence in the world, well above Spain, the United States and similar to a
study in India
Further insight into the geographic distribution of Leishmania species in Peru by cytochrome b and mannose phosphate isomerase gene analyses.
To obtain further insight into geographic distribution of Leishmania species in Peru, a countrywide survey, including central to southern rainforest areas where information on causative parasite species is limited, was performed based on cytochrome b (cyt b) and mannose phosphate isomerase (mpi) gene analyses. A total of 262 clinical samples were collected from patients suspected of cutaneous leishmaniasis (CL) in 28 provinces of 13 departments, of which 99 samples were impregnated on FTA (Flinders Technology Associates) cards and 163 samples were Giemsa-stained smears. Leishmania species were successfully identified in 83 (83.8%) of FTA-spotted samples and 59 (36.2%) of Giemsa-stained smear samples. Among the 142 samples identified, the most dominant species was Leishmania (Viannia) braziliensis (47.2%), followed by L. (V.) peruviana (26.1%), and others were L. (V.) guyanensis, L. (V.) lainsoni, L. (V.) shawi, a hybrid of L. (V.) braziliensis and L. (V.) peruviana, and Leishmania (Leishmania) amazonensis. Besides the present epidemiological observations, the current study provided the following findings: 1) A hybrid of L. (V.) braziliensis and L. (V.) peruviana is present outside the Department of Huanuco, the only place reported, 2) Many cases of CL due to L. (V.) lainsoni, an uncommon causative species in Peru, were observed, and 3) L. (V.) shawi is widely circulating in southern Amazonian areas in Peru