The State's Losses at State-owned Enterprises in Persfektif Corruption

State-Owned Enterprises administered by the professional who works with rule and regulation. Steps in the form of profit in money terms, it is not independent of the existence of the risk in the form of the possibility of losses. In carrying out the actions of The State-Owned Enterprises have always been faced with the possibility of obtaining profits or suffer losses. Therefore, the losses that occur in professional decision making should not be casually (not necessarily should) be considered as a deliberate act which is equivalent to committing financial fraudProblem management to State-Owned Enterprises and refines that may give rise to uncertainties in law enforcement corruption, losses arising on a transaction conducted by the perpetrators of State-Owned Enterprises was acts that inflict such losses can be seen as a disadvantage the SOES can be raises the loss of State-Owned Enterprises, considering it as a business entity is seeking a profit, which in its management could be profit or loss depends on how could market mechanism

Establishing a Site-Specific Standard of Practice for Field Vane Shear Testing in Mine Tailings

The field vane shear test (FVT) provides the only direct measurement of in-situ yield and residual undrained shear strength and is widely used in geotechnical practice. However, use of this test in mine tailings requires modifications from the ASTM standard to achieve and maintain undrained conditions. This paper advances research presented in recent publications that identified concerns with the accuracy of data obtained in mine tailings using the ASTM standard, as well as those introducing high-speed FVT equipment and modified procedures for mine tailings applications. Herein, the authors present the results and interpretation of a field investigation program commissioned by a confidential mining client across multiple tailings storage facilities (TSFs). The investigation used these modified procedures and high-speed FVT equipment with the objective of mitigating risk associated with the uncertainty of whether FVT results used for selection of design parameters were in an undrained condition. To this end, a series of FVTs were performed at the same depths in adjacent soundings using a range of vane rotation rates for evaluation of both drainage and viscous effects on the measured yield and residual undrained shear strength. Companion cone penetration test (CPT) soundings with pore water pressure dissipation (PPD) tests were also conducted to support the characterization and interpretation. Results from this program demonstrate how the client, in a practical manner, was able to validate their standard of practice for high-speed FVT and determine optimal vane rotation rates that achieve undrained conditions while avoiding viscous effects for the various mine tailings across their portfolio of TSFs. For the mining industry, this provides a model for implementation of similar investigation programs at other TSFs to gain site-specific knowledge of vane rotation rate effects on the measured undrained shear strength for respective mine tailings, as well as a basis and directive for development of modified standards for mine tailings applications superseding the existing ASTM standard.Non UBCUnreviewedOthe

A mechanistic linkage between oral lichen planus and autoimmune thyroid disease

ObjectiveTo determine the levels of antithyroid antibodies and thyroid hormones in the sera of patients with oral lichen planus (OLP), and to quantify the expression of thyroid proteins in OLP lesions. Subjects and MethodsVenous blood samples were drawn from 110 patients with OLP who had no history of thyroid disease or levothyroxine supplementation (OLP+/LT4-). A random population sample of 657 healthy subjects was used as the control group. Two additional groups were used as comparators. Immunohistochemical and qPCR analyses were performed on tissue specimens collected from the patients with OLP and thyroid disease and healthy subjects. ResultsNo association was found between the presence of antithyroid antibodies and OLP. More patients in the OLP+/LT4- group showed high levels of thyroid-stimulating hormone and low levels of free thyroxine than were seen in the control group. Thyroid-stimulating hormone receptor was more highly expressed in the OLP lesions of patients with thyroid disease than in the healthy oral mucosa. ConclusionsA significant number of patients with OLP who are not previously diagnosed with thyroid disease have thyroid parameters that are compatible with hypothyroidism. The expression of thyroid-stimulating hormone receptor in OLP lesions suggests that mechanisms related to autoimmune thyroid disease are involved in the aetiology of OLP

Genetic and developmental disorders of the oral mucosa : epidemiology; molecular mechanisms; diagnostic criteria; management

A large number of disorders may affect the oral cavity, including genetic diseases, infections, cancers, blood diseases, skin diseases, endocrine and metabolic disorders, autoimmune and rheumatologic diseases, local lesions, to name a few. Oral mucosa shows a considerable variation in its normal structure and a wide range of conditions may affect it. Such conditions are often harmless or minor and could be primary or secondary to systemic disease. Several of them are quite rare and, hence, the diagnosis is not easy. Clinically, lesions may appear as ulcers, discoloration of the oral mucosa and alterations in size and configuration of oral anatomy. Genetic disorders have specific manifestations and can be caused by a derangement of one or more components of the tissue. Many of them follow the skin or systemic signs of the underlying genetic disease, but in a few cases oral signs could be the first manifestation of the disorder. Among them genodermatoses are prominent. They are inherited disorders characterized by a multisystem involvement. This review describes chondro-ectodermal dysplasia, dyskeratosis congenita, Ehlers-Danlos syndrome, hereditary benign intraepithelial dyskeratosis, keratosis follicularis, lipoid proteinosis, multiple hamartoma syndrome, pachyonychia congenita, Peutz-Jeghers syndrome, tuberous sclerosis and white sponge nevus. Other genetic disorders not included in the genodermatosis group and reported in the present review are: acanthosis nigricans, angio-osteo-hypertrophic syndrome, encephalotrigeminal angiomatosis, familial adenomatous polyposis, focal dermal hypoplasia, focal palmoplantar and oral mucosa hyperkeratosis syndrome, gingival fibromatosis, Maffucci's syndrome, neurofibromatosis (type 1) and oro-facial-digital syndrome (type 1). Disorders during embryonic development might lead to a wide range of abnormalities in the oral cavity; some of them are quite common but of negligible concern, whereas others are rare but serious, affecting not only the oral mucosa, but also other structures of the oral cavity (ie palate, tongue and gingiva). Fordyce's granules, leukoedema, cysts of the oral mucosa in newborns, retrocuspid papilla, geographic tongue, fissured tongue, median rhomboid glossitis, hairy tongue, lingual varices and lingual thyroid nodule are described. This review may help dentists, dental hygienists, but also general internists and pediatricians to diagnose different disorders of the oral mucosa, to understand the pathogenesis and to schedule a treatment plan