Applications Of Autonomous Microfluidic Systems In Environmental Monitoring

Concern about the environment is increasing and so is the search for analytical methods that make continuous monitoring possible. Microfluidic devices such as lab-on-a-chip emerge as an alternative to the laboratory-based conventional techniques, making possible the development of unmanned monitoring tools. This review covers the last five years on the application of autonomous microfluidic devices for continuous environmental monitoring and addresses the existing demands in this field. © 2013 The Royal Society of Chemistry.3401821618227Delattre, C., Allier, C.P., Fouillet, Y., Jary, D., Bottausci, F., Bouvier, D., Delapierre, G., Peponnet, C., (2012) Biosens. Bioelectron., 36, pp. 230-235Beaton, A.D., Cardwell, C.L., Thomas, R.S., Sieben, V.J., Legiret, F.E., Waugh, E.M., Statham, P.J., Morgan, H., (2012) Environ. Sci. Technol., 46, pp. 9548-9556Jang, A., Zou, Z., Lee, K.K., Ahn, C.H., Bishop, P.L., (2011) Meas. Sci. Technol., 22, p. 032001Li, H.F., Lin, J.M., (2009) Anal. Bioanal. 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Comparison Of Potassium And Sodium Content In Diet And Non-diet Soft Drinks By Using Capillary Electrophoresis With Capacitively Coupled Contactless Conductivity Detection

Capillary electrophoresis (CE) with capacitively coupled contactless conductivity detection (C4D) was used for determination of sodium and potassium concentrations in diet and non-diet soft drinks. Higher sodium concentrations were found in the diet samples due to the utilization of sodium salts of cyclamate and saccharine as sweeteners. The CE-C 4D method can be used by food industries and health regulatory agencies for monitoring sodium and potassium content, not only in soft drink but in many others food products.3435156Macgregor, G.A., (2001) Am. J. Kidney Dis., 37, pp. S34He, F.J., MacGregor, G.A., (2001) Br. Med. J., 323, p. 497Toseto, A., (2005), Master's Dissertation, Universidade Estadual de Ponta Grossa, BrazilTavares, M.F.M., (1996) Quim. Nova, 19, p. 173Jorgenson, J.W., Lukacs, K.D., (1981) Anal. Chem., 53, p. 1298Da Silva, J.A.F., Lago, C.L., (1998) Anal. Chem., 70, p. 4339Silva, J.A.F.D., Guzman, N., Lago, C.L., (2002) J. Chromatogr. a, 942, p. 249Munhõz, R.A.A., Richter, E.M., Jesus, D.P., Lago, C.L., Angnes, L., (2004) J. Braz. Chem. Soc., 15, p. 523Richter, E.M., Munhõz, R.A.A., Jesus, D.P., Lago, C.L., Angnes, L., (2005) J. Braz. Chem. Soc., 16, p. 1134Carvalho, A.Z., Da Silva, J.A.F., Lago, C.L., (2003) Electrophoresis, 24, p. 2138Gong, X.Y., Hauser, P.C., (2006) Electrophoresis, 27, p. 468Samcova, E., Tuma, P., (2006) Electrophoresis, 18, p. 15

No ritmo das águas do pantanal

Texto en Portugué

Real-time Monitoring Of Binding Assays On Microfluidic Devices With Contactless Conductivity Detection

This work describes the development of a dual capacitively coupled contactless conductivity detection (C4D) system and its application to monitor binding assays on microfluidic devices. Microfluidic devices were fabricated in poly(dimethylsiloxane) (PDMS) and sealed against a glass plate containing patterned electrodes. Before the sealing step, the electrodes were insulated from the contact with the microchannel by a thin layer of silicon oxide. The avidin-biotin complex was used as model system to demonstrate the analytical feasibility of the proposed system. © 2008 CBMS.742744Dostalek, J., Homola, J., Surface plasmon resonance sensor based on an array of diffraction gratings for highly parallelized observation of biomolecular interactions (2008) Sens. Actuators B, 129, pp. 303-310Pumera, M., Contactless conductivity detection for microfluidics: Designs and applications (2007) Talanta, 74, pp. 358-364Fracassi Da Silva, J.A., Do Lago, C.L., An oscillometric detector for capillary electrophoresis (1998) Anal. Chem., 70, pp. 4339-434

Surface Modification Of Pdms Microchips With Poly(ethylene Glycol) Derivatives For μtas Applications

In this work is presented a method for the modification of native PDMS surface in order to improve its applicability as a substrate for microfluidic devices, especially in the analysis of nonpolar analytes. Therefore, poly(ethylene glycol) divinyl ether modified PDMS substrate was obtained by surface modification of native PDMS. The modified substrate was characterized by attenuated total reflectance infrared spectroscopy, water contact angle measurements, and by evaluating the adsorption of rhodamine B and the magnitude of the EOF mobility. The reaction was confirmed by the spectroscopic evaluation. The formation of a well-spread water film over the surface immediately after the modification was an indicative of the modified surface hydrophilicity. This characteristic was maintained for approximately ten days, with a gradual return to a hydrophobic state. Fluorescence assays showed that the nonpolar adsorption property of PDMS was significantly decreased. 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