On the Future of Internet Governance

These proceedings represent the perspectives and views of several experts and participants in the Internet Governance and ICANN process of the late 1990s and early 2000s

A Programme for Women achieving Excellence in Research (PoWER): theoretically informed intervention design and evaluation

Academics in Higher Education are often expected both to teach and to research; this is a particular challenge for women both structurally and individually. Initiatives to address structural issues include AdvanceHE. Here, we focus on individual issues and report on the Programme for Women Achieving Excellence in Research, a theory-based intervention. Barriers to success were assessed and course content tailored accordingly. Evaluation demonstrated that barriers were reduced and that confidence increased. Although the barriers are both individual and contextual, our rigorous approach allows international application through intervention modification without loss of fidelity. This offers a new approach for academic developers to enable female researchers

Promotion Effect of Alkali Metal Hydroxides on Polymer-Stabilized Pd Nanoparticles for Selective Hydrogenation of C–C Triple Bonds in Alkynols

Postimpregnation of Pd nanoparticles (NPs) stabilized within hyper-cross-linked polystyrene with sodium or potassium hydroxides of optimal concentration was found to significantly increase the catalytic activity for the partial hydrogenation of the C–C triple bond in 2-methyl-3-butyn-2-ol at ambient hydrogen pressure. The alkali metal hydroxide accelerates the transformation of the residual Pd(II) salt into Pd(0) NPs and diminishes the reaction induction period. In addition, the selectivity to the desired 2-methyl-3-buten-2-ol increases with the K- and Na-doped catalysts from 97.0 up to 99.5%. This effect was assigned to interactions of the alkali metal ions with the Pd NPs surfaces resulting in the sites’ separation and a change of reactants adsorption

Murine Models and Cell Lines for the Investigation of Pheochromocytoma: Applications for Future Therapies?

Pheochromocytomas (PCCs) are slow-growing neuroendocrine tumors arising from adrenal chromaffin cells. Tumors arising from extra-adrenal chromaffin cells are called paragangliomas. Metastases can occur up to approximately 60% or even more in specific subgroups of patients. There are still no well-established and clinically accepted “metastatic” markers available to determine whether a primary tumor is or will become malignant. Surgical resection is the most common treatment for non-metastatic PCCs, but no standard treatment/regimen is available for metastatic PCC. To investigate what kind of therapies are suitable for the treatment of metastatic PCC, animal models or cell lines are very useful. Over the last two decades, various mouse and rat models have been created presenting with PCC, which include models presenting tumors that are to a certain degree biochemically and/or molecularly similar to human PCC, and develop metastases. To be able to investigate which chemotherapeutic options could be useful for the treatment of metastatic PCC, cell lines such as mouse pheochromocytoma (MPC) and mouse tumor tissue (MTT) cells have been recently introduced and they both showed metastatic behavior. It appears these MPC and MTT cells are biochemically and molecularly similar to some human PCCs, are easily visualized by different imaging techniques, and respond to different therapies. These studies also indicate that some mouse models and both mouse PCC cell lines are suitable for testing new therapies for metastatic PCC

Privacy Protection: Time to Think and Act Locally and Globally (originally published in June 1998)

This paper is included in the First Monday Special Issue: Commercial Applications of the Internet, published in July 2006. What sorts of privacy can consumers expect on the Internet? How havepolicies been evolving - or not evolving - in the past twelve months? This article examines the unique aspects on online communications and interactivity and analyzes the real meaning of community in the context of the Internet.[1

Release 2.0 : A design for living in the digital age

New Yorkviii, 307 p.; 24 cm