29 research outputs found
Health follow-up of children in poverty situation: between the routine and eventuality of daily care
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Structure and Behavior of Human α-Thrombin upon Ligand Recognition: Thermodynamic and Molecular Dynamics Studies
- Author
- A Doerr
- A Guinier
- AO Pineda
- AO Pineda
- AP Valente
- AV Semenyuk
- AV Wolf
- B Hess
- BC Lechtenberg
- BL De Groot
- C Kettner
- CE Di
- CH Croy
- CM Wells
- CN Pace
- CN Pace
- D Svergun
- D Van der Spoel
- DG Nair
- DI Svergun
- DJ Johnson
- DW Banner
- E Mylonas
- FV De
- G Kellermann
- GI Makhatadze
- GI Makhatadze
- GM Giesel
- Guilherme M. Giesel
- HJC Berendsen
- HJC Berendsen
- Hugo Verli
- I Melnikova
- JA Huntington
- Jie Zheng
- JK Myers
- JW Fenton
- K WĂŒthrich
- L Holm
- Leonardo C. Palmieri
- LM Lima
- LMTR Lima
- Luis Mauricio T. R. Lima
- M Gralle
- Maria Thereza Cargnelutti
- MM Santoro
- MT Stubbs
- MV Petoukhov
- N Mackman
- O Norberto de Souza
- OKT Bieri
- PK Ngai
- R Mohana-Borges
- R Mohana-Borges
- RF Greene Jr
- RG Kirste
- Robson Q. Monteiro
- RQ Monteiro
- RS Bauer
- RS Berry
- S Srivastava
- T Darden
- TL Chang
- Vivian de Almeira Silva
- W Bode
- W Bode
- WF van Gunsteren
- WJ Carter
- X Mao
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
Thrombin is a serine proteinase that plays a fundamental role in coagulation. In this study, we address the effects of ligand site recognition by alpha-thrombin on conformation and energetics in solution. Active site occupation induces large changes in secondary structure content in thrombin as shown by circular dichroism. Thrombin-D-Phe-Pro-Arg-chloromethyl ketone (PPACK) exhibits enhanced equilibrium and kinetic stability compared to free thrombin, whose difference is rooted in the unfolding step. Small-angle X-ray scattering (SAXS) measurements in solution reveal an overall similarity in the molecular envelope of thrombin and thrombin-PPACK, which differs from the crystal structure of thrombin. Molecular dynamics simulations performed with thrombin lead to different conformations than the one observed in the crystal structure. These data shed light on the diversity of thrombin conformers not previously observed in crystal structures with distinguished catalytic and conformational behaviors, which might have direct implications on novel strategies to design direct thrombin inhibitors
Déficit nutricional em crianças de uma cidade de grande porte do interior da Bahia, Brasil
- Author
- Azenha VM
- Barroso GS
- Black RE
- Daiene Rosa Gomes
- Elizia SimÔes Castelão
- Felisbino-Mendes MS
- Garbugio TLS
- Gilmar MercĂȘs de Jesus
- Graciete Oliveira Vieira
- Hosmer DW
- Jesus GM
- Lima AM
- Martins IS
- Monteiro CA
- Motta MEFA
- Nudelmann C
- Oliveira NF
- Oliveira VA
- Paz MGA
- Pinho CPS
- Rugolo LMSS
- Santos RB
- Sarni ROS
- Silveira KBR
- Tatiana de Oliveira Vieira
- Victora CG
- Yamamoto RM
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Characterization of the deposition of collagen fibers and Lithogenic potential in bladder of rats submitted to a sugar cane biopolymer graft
- Author
- Alves A
- Arlindo Monteiro de Carvalho Junior
- Beda Barros Barkokébas
- Castro CM
- Cavalcante AH
- Chagas HM
- Chagas HM
- Coelho MC
- Dambros M
- Delesse M
- Ewald E
- Fortes MA
- Garcia Y
- Jin S
- José Lamartine de Andrade Aguiar
- Klemm D
- Kosan M
- Lima SV
- Lopes LM
- Lucena RG.
- Marina Moura Santos
- Melo FA
- Miriam Dambros
- Morris MC
- Nemetz AP
- Pattison M
- Rangel AE
- Salvador Vilar Correia Lima
- Scherle W
- Stewart DW
- Sutherland IW
- Svensson A
- Vilar FO
- Vilar FO
- Vilar FO
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
The effects of nitric oxide on the immune system during Trypanosoma cruzi infection
- Author
- Abrahamsohn IA
- Adams LB
- Aliberti JC
- Aliberti JC
- Altclas J
- Alvarez MN
- Angelo M
- Arantes RM
- Baez AL
- Banick PD
- Benevides L
- Biffl WL
- Bogdan C
- Brunet LR
- Buscaglia CA
- Camargo MM
- Campos MA
- Cançado JR
- Cardoni RL
- Carneiro-Sampaio M
- Cattell V
- Chen B
- Chung HT
- Ciccarelli A
- Colasanti M
- Coura JR
- Cuzzocrea S
- Dal Secco D
- De Gouw HW
- De Groote MA
- Denkers EY
- Docampo R
- Eckmann L
- El Kasmi KC
- Fang FC
- Filardi LS
- Fredy RS Gutierrez
- Freire-de-Lima CG
- Fukada SY
- Furchgott RF
- Galvao LM
- Garg N
- Ghafourifar P
- Gilroy DW
- Goldstein J
- Gow AJ
- Gregory DJ
- Grisham MB
- Gu Z
- Guedes PMM
- Gutierrez FR
- Hokari R
- Huerta S
- James SL
- Jana M
- Johann AM
- JoĂŁo S Silva
- Kanneganti TD
- Klotz FW
- Larrainzar E
- Leiriao P
- Livonesi MC
- Lizasoain I
- Mach F
- Machado FS
- Machado FS
- MacMicking J
- Malvezi AD
- Mariano FS
- Marnett LJ
- Martins GA
- Melino G
- Michailowsky V
- Molina J
- Monteiro AC
- Murad F
- Murray HW
- Nathan C
- Niedbala W
- Nisoli E
- Okuda Y
- Packard KA
- Pahan K
- Paulo MM Guedes
- Paveto C
- Pereira CA
- Pfeilschifter J
- Piacenza L
- Poderoso JJ
- Poulos TL
- Rassi A
- Ribeiro JM
- Richardson DR
- Ridnour LA
- Rodriguez PC
- Russo M
- Russomando G
- Sakaguchi S
- Salvucci O
- Sato E
- Savino W
- Schnare M
- Schwarcz de Tarlovsky MN
- Shi CS
- Shibata T
- Silva JJ
- Silva JS
- Silva JS
- Singh VK
- Sosa Estani S
- Staykova MA
- Stenger S
- Tarleton RL
- Taylor-Robinson AW
- Teixeira MM
- Tiago WP Mineo
- Trujillo M
- Underhill DM
- Urbina JA
- Uyemura SA
- van der Veen RC
- van Wely CA
- Venturini G
- Vespa GN
- Vyatkina G
- Wander R Pavanelli
- Wen JJ
- Wynn TA
- Xiao BG
- Xie QW
- Yeh CL
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Lutzomyia longipalpis urbanisation and control
- Author
- Acosta LA
- Afonso MMS
- Aguilar CM
- Alexander B
- Alexander B
- Alexander B
- Alexander B
- Almeida PS
- Almeida PS
- Alves GB
- Alves WA
- Andrade AR
- Andrade Filho JD
- Arias JR
- Arrivillaga J
- Arrivillaga J
- Arrivillaga J
- Barata RA
- Barata RA
- Bauzer LGSR
- Bejarano EE
- Belo VS
- Belo VS
- Bevilacqua PD
- Bravo AG
- Bray DP
- Bray DP
- Bray DP
- Brazil RP
- Brazil RP
- Brazil RP
- Brazil RP
- Brazil RP
- Camargo-Neves VLF
- Campos AM
- Campos MP
- Canese A
- Canese A
- Canese J
- Cardim MF
- Carrillo J
- Carvalho BM
- Carvalho GM
- Carvalho MR
- Casanova C
- Casanova C
- Cerbino Neto J
- Colla-Jacques FE
- Correa-Antonialli SA
- Cortes LA
- Costa CH
- Costa CH
- Costa PL
- Courtenay O
- Cousiño B
- Curtis CF
- Dantas-Torres F
- Davies CR
- De Silans LNMP
- Deane LM
- Deane LM
- Deane LM
- Delgado O
- Desjeux P
- Dias ES
- Duarte Z
- Elizabeth Ferreira Rangel
- Feliciangeli MD
- Feliciangeli MD
- Feliciangeli MD
- Feliciangeli MD
- Feliciangeli MD
- Feliciangeli MD
- Feliciangeli MD
- FernĂĄndez MS
- Ferreira AL
- Fischer D
- FlĂłrez M
- Forattini OP
- Gaglio G
- Galati EAB
- Gama MEA
- GarcĂa B
- Gomes AC
- GonzĂĄlez C
- Gould IT
- Holcman MM
- Kelly DW
- Killick-Kendrick R
- Lainson R
- Le Pont F
- Lima H
- Macedo-Silva VP
- Maia-Elkhoury AN
- Marcondes CB
- Marcondes CB
- Margarete Martins dos Santos Afonso
- Margonari C
- Maroli M
- MartĂn-SĂĄnchez J
- Marzochi MCA
- MarĂa Dora Feliciangeli
- MarĂa Gabriela Quintana
- Mestre GL
- Michalsky EM
- Michalsky EM
- Missawa NA
- Missawa NA
- Monteiro PS
- Morrison AC
- MĂĄrquez LM
- Nascimento BW
- Nascimento MD
- Nieto P
- Noyes H
- Oliveira AG
- Oliveira AG
- Oliveira AG
- Oliveira AG
- Oliveira CD
- Oliveira EF
- Oliveira EF
- Oscar Daniel SalomĂłn
- Paula MB
- Paula MB
- Perrotey S
- Peterkova-Koci K
- Pifano F
- Pinheiro MP
- Pinto IS
- Pita-Pereira D
- Queiroz MF
- Quesada BL
- Quintana MG
- Rangel EF
- Rangel O
- Reithinger R
- Rodrigues AA
- RodrĂguez NM
- Romero GA
- RĂȘgo FD
- SalomĂłn OD
- SalomĂłn OD
- SalomĂłn OD
- SalomĂłn OD
- SalomĂłn OD
- SalomĂłn OD
- SalomĂłn OD
- Santini MS
- Santini MS
- Santini MS
- Santos DR
- SantâAnna MR
- Saraiva L
- Silva GA
- Silva RA
- Soares BR
- Soares RP
- Souza CF
- Souza GD
- Spada JC
- Szelag EA
- Valderrama A
- vigilĂąncia Manual de
- Vilela ML
- Von Zuben AP
- Warburg A
- Zerpa O
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Avaliação de medidas de controle de flebotomĂneos no norte do Estado do ParanĂĄ, Brasil
- Author
- Ademar Rodrigues dos Santos
- Alencar JE
- Alencar JE
- Alexander B
- Alexander B
- Alexander B
- Ampuero J
- Campbell-Lendrum D
- Chavasse DC
- Davies CR
- Davies CR
- Demilson Rodrigues dos Santos
- Desjeux P
- FalcĂŁo AL
- FalcĂŁo AR
- Feliciangeli MD
- Floch H
- Galati EAB
- Herintha Coeto Neitzke
- JoĂŁo BalduĂno KĂŒhl
- Kelly DW
- Kroeger A
- Le Pont F
- Lima AP
- LuĂs Paschoal Poiani
- Marcondes CB
- Maria Valdrinez Campana Lonardoni
- Membrive NA
- Morsy TA
- OtĂlio de Oliveira
- Perich MJ
- Ready PD
- Sen Gupta PC
- Teodoro U
- Teodoro U
- Teodoro U
- Teodoro U
- Teodoro U
- Teodoro U
- Teodoro U
- Teodoro U
- Teodoro U
- ThaĂs Gomes Verzignassi Silveira
- Townson H
- Ueslei Teodoro
- Wuelton Marcelo Monteiro
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
- Author
- Abdel-Aziz AK
- Abdelfatah S
- Abdellatif M
- Abdoli A
- Abel S
- Abeliovich H
- Abildgaard MH
- Abudu YP
- Acevedo-Arozena A
- Adamopoulos IE
- Adeli K
- Adolph TE
- Adornetto A
- Aflaki E
- Agam G
- Agarwal A
- Aggarwal BB
- Agnello M
- Agostinis P
- Agrewala JN
- Agrotis A
- Aguilar PV
- Ahmad ST
- Ahmed ZM
- Ahumada-Castro U
- Aits S
- Aizawa S
- Akkoc Y
- Akoumianaki T
- Akpinar HA
- Al-Abd AM
- Al-Akra L
- Al-Gharaibeh A
- Alaoui-Jamali MA
- Alberti S
- Alcocer-GĂłmez E
- Alessandri C
- Ali M
- Alim Al-Bari MA
- Aliwaini S
- Alizadeh J
- Almacellas E
- Almasan A
- Alonso A
- Alonso GD
- Altan-Bonnet N
- Altieri DC
- Alves da Costa C
- Alves S
- Alzaharna MM
- Amadio M
- Amantini C
- Amaral C
- Ambrosio S
- Amer AO
- Ammanathan V
- An Z
- Andersen SU
- Andrabi SA
- Andrade-Silva M
- Andres AM
- Angelini S
- Ann D
- Anozie UC
- Ansari MY
- Antas P
- Antebi A
- AntĂłn Z
- Anwar T
- Apetoh L
- Apostolova N
- Araki T
- Araki Y
- Arasaki K
- Araya J
- AraĂșjo WL
- Arden C
- Arguelles S
- Arias E
- Arikkath J
- Arimoto H
- Ariosa AR
- Armstrong-James D
- Arnauné-Pelloquin L
- Aroca A
- Arroyo DS
- Arsov I
- Artero R
- Arévalo M-A
- Asaro DML
- Aschner M
- Ashrafizadeh M
- Ashur-Fabian O
- Atanasov AG
- Au AK
- Auberger P
- Auner HW
- Aurelian L
- Autelli R
- Avagliano L
- Aveic S
- Aveleira CA
- Avin-Wittenberg T
- Aydin Y
- Ayton S
- Ayyadevara S
- Azzopardi M
- Baba M
- Backer JM
- Backues SK
- Bae D-H
- Bae O-N
- Bae SH
- Baehrecke EH
- Baek A
- Baek S-H
- Baek SH
- Bagetta G
- Bagniewska-Zadworna A
- Bai H
- Bai J
- Bai X
- Bai Y
- Bairagi N
- Baksi S
- Balazadeh S
- Balbi T
- Baldari CT
- Balduini W
- Ballabio A
- Ballester M
- Balzan R
- Bandopadhyay R
- Banerjee S
- Banerjee S
- Bao Y
- Baptista MS
- Baracca A
- Barbati C
- Bargiela A
- BarilĂ D
- Barlow PG
- Barmada SJ
- Barreiro E
- Barreto GE
- Bartek J
- Bartel B
- Bartolome A
- Barve GR
- Basagoudanavar SH
- Bassham DC
- Bast RC
- Basu A
- Batoko H
- Batten I
- Baulieu EE
- Baumgarner BL
- Bayry J
- Beale R
- Beau I
- Beaumatin F
- Bechara LRG
- Beck GR
- Beers MF
- Begun J
- Behl C
- Behrends C
- Behrens GMN
- Bei R
- Bejarano E
- Bel S
- Belaid A
- Belgareh-Touzé N
- Bellarosa C
- Belleudi F
- Bello-Morales R
- BellĂł PĂ©rez M
- Beltran JSDO
- Beltran S
- Benbrook DM
- Bendorius M
- Benitez BA
- Benito-Cuesta I
- Bensalem J
- Berchtold MW
- Berezowska S
- Bergamaschi D
- Bergami M
- Bergmann A
- Berliocchi L
- Berlioz-Torrent C
- Bernard A
- Berthoux L
- Besirli CG
- Besteiro S
- Betin VM
- Beyaert R
- Bezbradica JS
- Bhaskar K
- Bhatia-Kissova I
- Bhattacharya R
- Bhattacharya S
- Bhattacharyya S
- Bhuiyan MS
- Bhutia SK
- Bi L
- Bi X
- Biden TJ
- Bijian K
- Billes VA
- Binart N
- Bincoletto C
- Birgisdottir AB
- Bjorkoy G
- Blanco G
- Blas-Garcia A
- Blasiak J
- Blomgran R
- Blomgren K
- Blum JS
- Boada-Romero E
- Boban M
- Boesze-Battaglia K
- Boeuf P
- Boland B
- Bomont P
- Bonaldo P
- Bonam SR
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- Bonifacino JS
- Boone BA
- Bootman MD
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- Borner C
- Bornhauser BC
- Borthakur G
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- Botana LM
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- Bourgeois B
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- Bozhkov PV
- Bozi LHM
- Bozkurt TO
- Brackney DE
- Brand-Saberi B
- Brandts CH
- Braun RJ
- Braus GH
- Bravo-Sagua R
- Bravo-San Pedro JM
- Brest P
- Bringer M-A
- Briones-Herrera A
- Broaddus VC
- Brodersen P
- Brodsky JL
- Brody SL
- Bronson PG
- Bronstein JM
- Brown CN
- Brown RE
- Brum PC
- Brumell JH
- Brunetti-Pierri N
- Bruno D
- Bryson-Richardson RJ
- Bucci C
- Buch S
- Buchan JR
- Buchrieser C
- Buckingham EM
- Budak H
- Budini M
- Bueno M
- Buitrago-Molina LE
- Bultynck G
- Burada F
- Buraschi S
- Burgoyne JR
- BurĂłn MI
- Bustos V
- Butturini E
- Byrd A
- BĂĄnrĂ©ti Ă
- BĂŒttner S
- Cabas I
- Cabrera-Benitez S
- Cadwell K
- Cai J
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- Caldwell GA
- Caldwell KA
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- Calvani R
- Calvo AC
- Calvo-Rubio Barrera M
- Camara NO
- Camonis JH
- Camougrand N
- Campanella M
- Campbell EM
- Campbell-Valois F-X
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- Campos JC
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- Cancino J
- Candido de Almeida D
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- Caniggia I
- Canonico B
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- Cao B
- Caraglia M
- Caramés B
- Carchman EH
- Cardenal-Muñoz E
- Cardenas C
- Cardenas L
- Cardoso SM
- Carew JS
- Carle GF
- Carleton G
- Carloni S
- Carmona-Gutierrez D
- Carneiro LA
- Carnevali O
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- Carrier A
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- Catz SD
- Cavadas C
- Cavaliere F
- Cavallini G
- Cavinato M
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- Cebollada Rica P
- Cecarini V
- Cecconi F
- Cechowska-Pasko M
- Cenci S
- Ceperuelo-Mallafré V
- Cerqueira JJ
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- Cervia D
- Cetintas VB
- Cetrullo S
- Chae H-J
- Chagin AS
- Chai C-Y
- Chakrabarti G
- Chakrabarti O
- Chakraborty T
- Chakraborty T
- Chami M
- Chamilos G
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- Chatterjee S
- Chaube SK
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- Chen Z-H
- Chen ZJ
- Chen ZS
- Cheng H
- Cheng J
- Cheng S-Y
- Cheng W
- Cheng X
- Cheng X-T
- Cheng Y
- Cheng Z
- Cheong H
- Cheong JK
- Chernyak BV
- Cherry S
- Cheung CFR
- Cheung CHA
- Cheung K-H
- Chevet E
- Chi RJ
- Chiang AKS
- Chiaradonna F
- Chiarelli R
- Chiariello M
- Chica N
- Chiocca S
- Chiong M
- Chiou S-H
- Chiramel AI
- ChiurchiĂč V
- Cho D-H
- Choe S-K
- Choi AMK
- Choi ME
- Choudhury KR
- Chow NS
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- Chua JJE
- Chua JP
- Chung H
- Chung KP
- Chung S
- Chung S-H
- Chung Y-L
- Cianfanelli V
- Ciechomska IA
- Cifuentes M
- Cinque L
- Cirak S
- Cirone M
- Clague MJ
- Clarke R
- Clementi E
- Coccia EM
- Codogno P
- Cohen E
- Cohen MM
- Colasanti T
- Colasuonno F
- Colbert RA
- Colell A
- Coll NS
- Collins MO
- Colombo MI
- ColĂłn-Ramos DA
- Combaret L
- Comincini S
- Cominetti MR
- Consiglio A
- Conte A
- Conti F
- Contu VR
- Cookson MR
- Coombs KM
- Coppens I
- Corasaniti MT
- Cordes N
- Corkery DP
- Cortese K
- Costa MDC
- Costantino S
- Costelli P
- Coto-Montes A
- Crack PJ
- Crespo JL
- Criollo A
- Crippa V
- Cristofani R
- Csizmadia T
- Cuadrado A
- Cui B
- Cui J
- Cui Y
- Cui Y
- Culetto E
- Cumino AC
- Cybulsky AV
- Czaja MJ
- Czuczwar SJ
- D'Adamo S
- D'Amelio M
- D'Arcangelo D
- D'Lugos AC
- D'Orazi G
- da Silva JA
- Dafsari HS
- Dagda RK
- Dagdas Y
- Daglia M
- Dai X
- Dai Y
- Dai Y
- Dal Col J
- Dalhaimer P
- Dalla Valle L
- Dallenga T
- Dalmasso G
- Damme M
- Dando I
- Dantuma NP
- Darling AL
- Das H
- Dasarathy S
- Dasari SK
- Dash S
- Daumke O
- Dauphinee AN
- Davies JS
- Davis RJ
- Davis T
- Dayalan Naidu S
- De Amicis F
- De Bosscher K
- De Felice F
- De Franceschi L
- De Leonibus C
- de Mattos Barbosa MG
- De Meyer GRY
- De Milito A
- De Nunzio C
- De Palma C
- De Santi M
- De Virgilio C
- De Zio D
- Debnath J
- DeBosch BJ
- Decuypere J-P
- Deehan MA
- Deflorian G
- DeGregori J
- Dehay B
- Del Rio G
- Delaney JR
- Delbridge LMD
- Delorme-Axford E
- Delpino MV
- Demarchi F
- Dembitz V
- Demers ND
- Deng H
- Deng Z
- Dengjel J
- Dent P
- Denton D
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- Ălvarez ĂMC
- Ăvalos Y
- Ănal G
- ĂstĂŒn S
- ÄoliÄ M
- ÄokiÄ J
- Ćœerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
High-Speed, SAD Based Wavefront Sensor Architecture Implementation on FPGA
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Is there any influence of breastfeeding on the cerebral blood flow? A review of 256 healthy newborns
- Author
- Alexandra Maria Vieira Monteiro
- Allison JW
- Aranha CA
- Busija DW
- Claudio Marcio Amaral de Oliveira Lima
- Coombs RC
- Daffertshofer M
- Deeg KH
- Gabriel ML
- Garcia MHM
- Garcia RF
- Gardiner RM
- Geneslaw AS
- Gladman G
- Gosling RG
- Hallacoglu B
- Hill PD
- Hsu CH
- Kusaka T
- Martinussen M
- Mchedlishvili G
- Monteiro AMV
- Moron AF
- Ozkan H
- Paula Medina
- Paulson OB
- Pezzati M
- Pourcelot L.
- Robel-Tillig E
- Simpson DM
- Van Bel F
- Volpe JJ
- Wilson MH
- Publication venue
- Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
- Publication date
- 01/10/2012
- Field of study
OBJECTIVE: To investigate whether breastfeeding influence the cerebral blood-flow velocity. MATERIALS AND METHODS: The present study included 256 healthy term neonates, all of them with appropriate weight for gestational age, 50.8% being female. Pulsatility index, resistance index and mean velocity were measured during breastfeeding or resting in the anterior cerebral artery, in the left middle cerebral artery, and in the right middle cerebral artery of the neonates between their first 10 and 48 hours of life. The data were analyzed by means of a paired t-test, Brieger's f-test for analysis of variance and linear regression, with p < 0.01 being accepted as statistically significant. RESULTS: Mean resistance index decreased as the mean velocity increased significantly during breastfeeding. Pulsatility index values decreased as much as the resistance index, but in the right middle cerebral artery it was not statistically significant. CONCLUSION: Breastfeeding influences the cerebral blood flow velocities