9 research outputs found

    Changing climate—changing pathogens: Toxoplasma gondii in North-Western Europe

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    In this review, we describe the effects of global climate change for one specific pathogen: the parasite Toxoplasma gondii. It is postulated that an increase of T. gondii prevalence in humans can occur in some regions of North-Western Europe as a result of changing environmental conditions. Such a change can be predicted by using Global Climate Change models. We have elaborated such a prediction for one scenario (SRES A1) by using one specific model (CCSR/NRIES) as an example. Next to environmental factors, also anthropogenic factors may contribute to increased prevalence of T. gondii in this region. In order to counter the potential severe consequences of a potential increase resulting from the combination of climatic and anthropogenic factors, there is an urgent need for the development of a human vaccine. Until a vaccine that offers complete protection is developed, the emphasis should be on treatment optimization and prevention

    Prospects for a human Toxoplasma vaccine

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    Immunosuppressive drugs as a tool to explore immunopathology in experimental Chagas disease

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    Submitted by Sandra Infurna ([email protected]) on 2020-06-07T12:55:55Z No. of bitstreams: 1 KatiaS_Calabrese_IOC_1999.pdf: 38451 bytes, checksum: 8ff072aabd0a77c14ab182f9a4301727 (MD5)Approved for entry into archive by Sandra Infurna ([email protected]) on 2020-06-07T13:07:38Z (GMT) No. of bitstreams: 1 KatiaS_Calabrese_IOC_1999.pdf: 38451 bytes, checksum: 8ff072aabd0a77c14ab182f9a4301727 (MD5)Made available in DSpace on 2020-06-07T13:07:38Z (GMT). No. of bitstreams: 1 KatiaS_Calabrese_IOC_1999.pdf: 38451 bytes, checksum: 8ff072aabd0a77c14ab182f9a4301727 (MD5) Previous issue date: 1999Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. LaboratĂłrio de Immunomodulação. Rio de Janeiro, RJ, Brasil

    Sexual Preferences in Nutrient Utilization Regulate Oxygen Consumption and Reactive Oxygen Species Generation in Schistosoma mansoni: Potential Implications for Parasite Redox Biology

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