Changing climate—changing pathogens: Toxoplasma gondii in North-Western Europe

In this review, we describe the effects of global climate change for one specific pathogen: the parasite Toxoplasma gondii. It is postulated that an increase of T. gondii prevalence in humans can occur in some regions of North-Western Europe as a result of changing environmental conditions. Such a change can be predicted by using Global Climate Change models. We have elaborated such a prediction for one scenario (SRES A1) by using one specific model (CCSR/NRIES) as an example. Next to environmental factors, also anthropogenic factors may contribute to increased prevalence of T. gondii in this region. In order to counter the potential severe consequences of a potential increase resulting from the combination of climatic and anthropogenic factors, there is an urgent need for the development of a human vaccine. Until a vaccine that offers complete protection is developed, the emphasis should be on treatment optimization and prevention

Prospects for a human Toxoplasma vaccine

International audienc

Immunosuppressive drugs as a tool to explore immunopathology in experimental Chagas disease

Submitted by Sandra Infurna ([email protected]) on 2020-06-07T12:55:55Z No. of bitstreams: 1 KatiaS_Calabrese_IOC_1999.pdf: 38451 bytes, checksum: 8ff072aabd0a77c14ab182f9a4301727 (MD5)Approved for entry into archive by Sandra Infurna ([email protected]) on 2020-06-07T13:07:38Z (GMT) No. of bitstreams: 1 KatiaS_Calabrese_IOC_1999.pdf: 38451 bytes, checksum: 8ff072aabd0a77c14ab182f9a4301727 (MD5)Made available in DSpace on 2020-06-07T13:07:38Z (GMT). No. of bitstreams: 1 KatiaS_Calabrese_IOC_1999.pdf: 38451 bytes, checksum: 8ff072aabd0a77c14ab182f9a4301727 (MD5) Previous issue date: 1999Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Laboratório de Immunomodulação. Rio de Janeiro, RJ, Brasil