Boundary element methods in the prediction of the acoustic damping of ship whipping vibrations

Damping of ship whipping vibrations following a slam due to wave impact is traditionally assumed to be primarily of material or structural origin. However, several mechanisms of energy dissipation to the surrounding water exist, including gravity and acoustic waves. Neither transports much energy for the lowest frequency modes, in which the acoustic wavelength may be an order or magnitude greater than the ship length whereas the gravity wavelength is at least an order of magnitude shorter than the ship beam. However, the acoustic damping ratio increases as the fourth power of frequency, becoming significant for higher frequency modes

An Experimental Investigation of Ride Control Algorithms for High-Speed Catamarans Part 1: Reduction of Ship Motions

Ride control systems are essential for comfort and operability of high-speed ships, but it remains an open question what is the optimum ride control method. To investigate the motions of a 112-m high-speed catamaran fitted with a ride control system, a 2.5-m model was tested in a towing tank. The model active control system comprised two transom stern tabs and a central T-Foil beneath the bow. Six ideal motion control feedback algorithms were used to activate the model scale ride control system and surfaces in a closed-loop control system: heave control, local motion control, and pitch control, each in a linear and nonlinear version. The responses were compared with the responses with inactive control surfaces and with no control surfaces fitted. The model was tested in head seas at different wave heights and frequencies and the heave and pitch response amplitude operators (RAOs), response phase operators, and acceleration response were measured. It was found that the passive ride control system reduced the peak heave and pitch motions only slightly. The heave and pitch motions were more strongly reduced by their respective control feedback. This was most evident with nonlinear pitch control, which reduced the maximum pitch RAO by around 50% and the vertical acceleration near the bow by about 40% in 60-mm waves (2.69 m at full scale). These reductions were influenced favorably by phase shifts in the model scale system, which effectively contributed both stiffness and damping in the control action

The influence of the centre bow and wet-deck geometry on motions of wave piercing catamarans

The effects of tunnel height and centre bow length on the motions of a 112-m wave-piercer catamaran with an above-water centre bow were investigated through model tests. Five alternative centre bow configurations were considered, and multiple series of model tests were conducted in regular head sea waves. The results showed that both heave and pitch increased over a wide range of wave encounter frequency as the wet-deck height of the catamaran model increased. However, increasing the length of the centre bow showed an increase in the pitch but a decrease in the heave for a limited range of wave encounter frequency near the heave and pitch resonance frequencies of the catamaran model. The positions of minimum vertical displacement were found to be aft of the longitudinal centre of gravity, between 20% and 38% of the overall length from the transom. Increase in the wet-deck height and consequently the archway clearance between the main hulls and centre bow also resulted in an increase in the vertical displacement relative to the undisturbed water surface in the centre bow area. The results also indicated the vulnerability to wet-deck slamming for the different bow and wet-deck designs

Enhancement of regression of cervical intraepithelial neoplasia II (moderate dysplasia) with topically applied all-trans-retinoic acid: a randomized trial.

BackgroundRetinoids enhance differentiation of most epithelial tissues. Epidemiologic studies have shown an inverse relationship between dietary intake or serum levels of vitamin A and the development of cervical dysplasia and/or cervical cancer. Pilot and phase I investigations demonstrated the feasibility of the local delivery of all-trans-retinoic acid (RA) to the cervix using a collagen sponge insert and cervical cap. A phase II trial produced a clinical complete response rate of 50%.PurposeThis randomized phase III trial was designed to determine whether topically applied RA reversed moderate cervical intraepithelial neoplasia (CIN) II or severe CIN.MethodsAnalyses were based on 301 women with CIN (moderate dysplasia, 151 women; severe dysplasia, 150 women), evaluated by serial colposcopy, Papanicolaou cytology, and cervical biopsy. Cervical caps with sponges containing either 1.0 mL of 0.372% beta-trans-RA or a placebo were inserted daily for 4 days when women entered the trial, and for 2 days at months 3 and 6. Patients receiving treatment and those receiving placebo were similar with respect to age, ethnicity, birth-control methods, histologic features of the endocervical biopsy specimen and koilocytotic atypia, and percentage of involvement of the cervix at study. Treatment effects were compared using Fisher's exact test and logistic regression methods. Side effects were recorded, and differences were compared using Fisher's exact test.ResultsRA increased the complete histologic regression rate of CIN II from 27% in the placebo group to 43% in the retinoic acid treatment group (P = .041). No treatment difference between the two arms was evident in the severe dysplasia group. More vaginal and vulvar side effects were seen in the patients receiving RA, but these effects were mild and reversible.ConclusionsA short course of locally applied RA can reverse CIN II, but not more advanced dysplasia, with acceptable local side effects.ImplicationsA derivative of vitamin A can reverse or suppress an epithelial preneoplasia, lending further support to the notion that chemoprevention of human cancer is feasible

Stabilising Lyme Regis – a strategic approach

Coastal erosion and landslides have been a constant threat to Lyme Regis in West Dorset, UK for over 250 years. By the 1980s, the frequency and scale of coastal erosion and land instability had reached a point whereby the local council realised that a change from the previous ad hoc repair and protection approach was needed to secure the long-term future of the town. An environmental improvements initiative was developed from then onwards to provide a strategic and integrated programme of coast protection and cliff stabilisation measures designed to mitigate the increasing threat of climate change, coastal erosion and landslides, while respecting the site’s unique heritage and environmental interests. This paper outlines the background and principal phases of the project that have been successfully delivered over the period 1990–2015

Many-particle entanglement with Bose--Einstein condensates

We propose a method to produce entangled states of several particles starting from a Bose-Einstein condensate. In the proposal, a single fast $\pi/2$ pulse is applied to the atoms and due to the collisional interaction, the subsequent free time evolution creates an entangled state involving all atoms in the condensate. The created entangled state is a spin-squeezed state which could be used to improve the sensitivity of atomic clocks.Comment: 4 pages. Minor modification

Sensory Electrical Stimulation Improves Foot Placement during Targeted Stepping Post-Stroke

Proper foot placement is vital for maintaining balance during walking, requiring the integration of multiple sensory signals with motor commands. Disruption of brain structures post-stroke likely alters the processing of sensory information by motor centers, interfering with precision control of foot placement and walking function for stroke survivors. In this study, we examined whether somatosensory stimulation, which improves functional movements of the paretic hand, could be used to improve foot placement of the paretic limb. Foot placement was evaluated before, during, and after application of somatosensory electrical stimulation to the paretic foot during a targeted stepping task. Starting from standing, twelve chronic stroke participants initiated movement with the non-paretic limb and stepped to one of five target locations projected onto the floor with distances normalized to the paretic stride length. Targeting error and lower extremity kinematics were used to assess changes in foot placement and limb control due to somatosensory stimulation. Significant reductions in placement error in the medial–lateral direction (p = 0.008) were observed during the stimulation and post-stimulation blocks. Seven participants, presenting with a hip circumduction walking pattern, had reductions (p = 0.008) in the magnitude and duration of hip abduction during swing with somatosensory stimulation. Reductions in circumduction correlated with both functional and clinical measures, with larger improvements observed in participants with greater impairment. The results of this study suggest that somatosensory stimulation of the paretic foot applied during movement can improve the precision control of foot placement

Clinical anxiety promotes excessive response inhibition

BACKGROUND: Laboratory tasks to delineate anxiety disorder features are used to refine classification and inform our understanding of etiological mechanisms. The present study examines laboratory measures of response inhibition, specifically the inhibition of a pre-potent motor response, in clinical anxiety. Data on associations between anxiety and response inhibition remain inconsistent, perhaps because of dissociable effects of clinical anxiety and experimentally manipulated state anxiety. Few studies directly assess the independent and interacting effects of these two anxiety types (state v. disorder) on response inhibition. The current study accomplished this goal, by manipulating state anxiety in healthy and clinically anxious individuals while they complete a response inhibition task. METHOD: The study employs the threat-of-shock paradigm, one of the best-established manipulations for robustly increasing state anxiety. Participants included 82 adults (41 healthy; 41 patients with an anxiety disorder). A go/nogo task with highly frequent go trials was administered during alternating periods of safety and shock threat. Signal detection theory was used to quantify response bias and signal-detection sensitivity. RESULTS: There were independent effects of anxiety and clinical anxiety on response inhibition. In both groups, heightened anxiety facilitated response inhibition, leading to reduced nogo commission errors. Compared with the healthy group, clinical anxiety was associated with excessive response inhibition and increased go omission errors in both the safe and threat conditions. CONCLUSIONS: Response inhibition and its impact on go omission errors appear to be a promising behavioral marker of clinical anxiety. These results have implications for a dimensional view of clinical anxiety