Should patients with synchronous colorectal liver metastases be offered liver resection?

The aim of this study was to evaluate the long-term outcome of patients with synchronous and metachronous colorectal liver metastases (CLRM) with an emphasis on prognostic factors for survival

NICEly does it: economic analysis within evidence-based clinical practice guidelines

There is increasing professional and policy interest in the role of clinical guidelines for promoting effective and efficient health care. The NHS Health Technology Assessment Programme identified an urgent need, when such guidelines are produced, to develop a framework and methods for incorporating the best evidence of effectiveness, taking into account information on cost-effectiveness. This paper describes the development of recent evidence-based guidelines, for use in primary care, which were the result of recent work by the North of England Guidelines Development Group. Their specific aim was to incorporate economic analysis into the guideline process and treatment recommendations. The introduction of economic data raised some methodological issues, specifically: in providing valid and generalisable cost estimates; in the grading of cost ‘evidence’; in finding a presentation helpful to clinicians. The approach used was to help clinicians aggregate the various attributes of treatment to make good treatment recommendations, rather than interpret cost-effectiveness ratios. In none of the guideline areas was there adequate information to estimate a cost per quality-adjusted-life-year. In the light of this research, future areas of work are identified and some recommendations are made for the forthcoming National Institute for Clinical Excellence.evidence-based medicine, economic evaluation, clinical guidelines, NICE

Aspects of the N=4 SYM amplitude -- Wilson polygon duality

We discuss formulation of Wilson polygon - MHV amplitude duality at the perturbative level in various regularizations. For four gluons it is shown that at one loop one can formulate diagrammatic correspondence interpolating between the dimensional regularization and the off-shell one. We suggest new interpretation of all types of box diagrams in terms of the dual simplex in dimensional regularization and describe its degeneration to the Wilson polygon. The interesting nullification phenomena for the low-energy amplitudes in the Higgsed phase has been found.Comment: 26 pages, 9 figure

Fragmentation, domain formation and atom number fluctuations of a two-species Bose-Einstein condensate in an optical lattice

We theoretically study the loading of a two-species Bose-Einstein condensate to an optical lattice in a tightly-confined one-dimensional trap. Due to quantum fluctuations the relative inter and intra species phase coherence between the atoms and the on-site atom number fluctuations are reduced in the miscible regime. For the immiscible case the fluctuations are enhanced and the atoms form metastable interleaved spatially separated domains where the domain length and its fluctuations are affected by quantum fluctuations.Comment: 32 page

The ISCIP Analyst, Volume IV, Issue 3

This repository item contains a single issue of The ISCIP Analyst, an analytical review journal published from 1996 to 2010 by the Boston University Institute for the Study of Conflict, Ideology, and Policy

The ISCIP Analyst, Volume IV, Issue 5

This repository item contains a single issue of The ISCIP Analyst, an analytical review journal published from 1996 to 2010 by the Boston University Institute for the Study of Conflict, Ideology, and Policy

The ISCIP Analyst, Volume IV, Issue 6

This repository item contains a single issue of The ISCIP Analyst, an analytical review journal published from 1996 to 2010 by the Boston University Institute for the Study of Conflict, Ideology, and Policy

The ISCIP Analyst, Volume IV, Issue 8

This repository item contains a single issue of The ISCIP Analyst, an analytical review journal published from 1996 to 2010 by the Boston University Institute for the Study of Conflict, Ideology, and Policy

The ISCIP Analyst, Volume IV, Issue 2

This repository item contains a single issue of The ISCIP Analyst, an analytical review journal published from 1996 to 2010 by the Boston University Institute for the Study of Conflict, Ideology, and Policy

The ISCIP Analyst, Volume III, Issue 18

This repository item contains a single issue of The ISCIP Analyst, an analytical review journal published from 1996 to 2010 by the Boston University Institute for the Study of Conflict, Ideology, and Policy