Investigación universitaria, clima y cultura organizacional en la Universidad César Vallejo – sede Lima Este – SJL

The essential purpose of the research was to study university research, the summit and organizational culture as factors that directly affect the formative process of university students in the Faculty of Engineering at the Universidad César Vallejo; It is necessary for the preparation of future professionals to be sustained on a solid scientific basis and the development of a research attitude that favors the generation of new knowledge and that the findings reaffirm the motivation and interest of the students and on the part of the university authorities to encourage and promote research that contributes to the improvement of the quality of life of the population as a whole. Being the basic type of study, of descriptive and correlational level, of non-experimental design, three instruments were applied for data collection and the Cronbach's Alpha reliability were for the university research variable (alpha=0.939); organizational climate (alpha=0.835) and organizational culture (alpha=0.947). Statistical correlations were evidenced between the variables university research and organizational climate with an rho=0.442 and p=0.000 while for university research and organizational culture with an rho=0.328 and p=0.000.La investigación que se realizó tuvo como propósito esencial estudiar la investigación universitaria, el cima y cultura organización como factores que inciden directamente en el proceso formativo de los estudiantes universitarios de la facultad de ingeniería de la Universidad César Vallejo; siendo está muy necesaria ya que la preparación de los futuros profesionales se sostengan sobre una sólida base científica y el desarrollo de una actitud investigativa que propenda la generación de nuevos conocimientos y que los hallazgos encontrados reafirmen la motivación e interés en los estudiantes y de parte de las autoridades universitarias el fomento y promoción de investigaciones que contribuyan a la mejora de la calidad de vida de la población en su conjunto. Siendo el tipo de estudio básico, de nivel descriptivo y correlacional, de diseño no experimental se aplicó tres instrumentos para la recolección de datos y la confiabilidad Alfa de Cronbach fueron para la variable investigación universitaria (alfa=0,939); clima organizacional (alfa=0,835) y cultura organizacional (alfa=0,947). Se evidenció las correlaciones estadísticas entre las variables investigación universitaria y clima organizacional con una rho=0,442 y p=0,000 mientras que para investigación universitaria y cultura organizacional con una rho=0,328 y p=0,000

Estrategia khan academy en el aprendizaje de la matemática en la educación básica: una revisión teórica

Education is understood as the pillar for the development of humanity as a whole to achieve the levels of welfare of nations, in that sense due to the progress of science and technology is made available to media and virtual environments that streamline the teaching-learning processes according to the demand of the population that requires better quality of learning systems and a flexible curriculum to meet the needs of the educational community. In this sense, the Khan Academy platform is a support that provides a set of systematized resources that makes it possible to raise the level of mathematical competencies of students in a highly competitive world; for this, the strategies designed should address as a priority the achievement of mathematical competencies of students in basic education with emphasis on autonomy and self-regulation of learning. The research methodology is based on documentary analysis, study of scientific papers, research articles and databases, the design is non-experimental, the applied method is inductive-deductive. The general objective was to analyze the Khan Academy strategy in the learning of mathematics in elementary education.La educación es entendida como el pilar para el desarrollo de la humanidad en su conjunto para alcanzar los niveles de bienestar de las naciones, en ese sentido debido al progreso de la ciencia y tecnología se pone al alcance de medios y entornos virtuales que dinamizan los procesos de enseñanza-aprendizaje acordes a la demanda de la población que requiere de una mejor calidad de los sistemas de aprendizaje y un currículo flexible para atender las necesidades de la comunidad educativa. En ese sentido, la plataforma Khan Academy es un soporte que brinda un conjunto de recursos sistematizados que posibilita elevar el nivel de competencias matemáticas de los estudiantes en un mundo altamente competitivo; para ello, las estrategias diseñadas deben abordar de manera prioritaria el logro de competencias matemáticas de los estudiantes de la educación básica con énfasis en la autonomía y autorregulación de aprendizajes. La metodología de la investigación se basa en el análisis documental, estudio de trabajos científicos, artículos de investigación y bases de datos, el diseño es no experimental, el método aplicado es el inductivo-deductivo. El objetivo general fue analizar la estrategia Khan Academy en el aprendizaje de la matemática en la educación básica

Medidas sanitarias adoptadas por el Estado para garantizar las diligencias fiscales frente a la crisis de salubridad

The research work established as a goal to explain the incidence of the measures taken by the Peruvian government, focusing mainly on the judicial field, being specific in the fiscal proceedings, taking into account that the mentioned measures will have a great impact on the sector.   The research is composed by a qualitative approach, of basic type and non-experimental design, in addition to the use of interviews applied to specialists in the field. The result, product of the researched and covered, manifests that the sanitary measures imposed by the government in front of the Coronavirus, did not transcend completely, so that the main judicial sector, see the case of the fiscal proceedings, these had many factors that prevented their development, for which the alternative of technological means was chosen, such as remote work, use of Gmail, Google Meet and WhatsApp; This was a favorable alternative, however, it did not generate the same results, in this sense the speed in person, as for the virtuality was the most frequently used mechanism in the actions of the administration of justice.El trabajo de investigación estableció como meta explicar la incidencia que ha tenido las medidas dispuestas por el gobierno del Perú, enfocándose principalmente en el ámbito judicial, siendo específicos en las diligencias fiscales, teniendo en cuenta que las medidas citadas tendrán un gran impacto en el sector.   La investigación está compuesta por un enfoque cualitativo, de tipo básica y diseño no experimental, además se hizo uso de la entrevista aplicada a especialistas en la materia. El resultado, producto de lo investigado y abarcado, manifiesta que las medidas sanitarias impuestas por el gobierno frente el Coronavirus, no trascendieron totalmente, de manera que el principal sector judicial, véase el caso de las diligencias fiscales, estas tuvieron muchos factores que impidieron su desenvolvimiento, por lo cual se optó por la alternativa de los medios tecnológicos, como el trabajo remoto, uso del Gmail, Google Meet y WhatsApp; que resultó una alternativa favorable, sin embargo no generó los mismos resultados, en tal sentido la celeridad de manera presencial, en cuanto a la virtualidad fue el mecanismo uso con mayor frecuencia en las acciones de la administración de justicia

Equilibrio ético para la toma de decisiones asistenciales en pacientes críticos. Hospital “Abel Santamaría”. 2005-2006.

A fin de caracterizar el  comportamiento del proceso de la toma de decisiones asistenciales con el paciente crítico en la Unidad de Cuidados Intensivos, se  realizó un estudio prospectivo, longitudinal y de intervención, en el cual se estudiaron dos cohortes  consecutivos  de pacientes (280 cada una). Se registraron todas las decisiones asistenciales y  procedimientos realizados en el  primer   periodo y  toma de decisiones alegórica al consentimiento informado e implicado. En un segundo período de intervención, con técnicas estratégicas especializadas, se solicitó a los pacientes (que tuviesen puntaje inferior a 50 puntos en la  escala de  Karnofky),  familiares y allegados su  consentimiento informado, volviéndose a registrar el número de procedimientos y de consentimientos informados individuales obtenidos.  Siempre que pudo ser posible, se le consultó el procedimiento a realizar al paciente y las acciones médicas. Cuando esto no fue posible, se tomó el criterio del familiar o allegado competente y en tercera instancia,  el criterio del consenso absoluto de todo el equipo asistencial de trabajo, el consentimiento implicado. Se obtuvo un tránsito en el protagonismo de las decisiones asistenciales con el paciente crítico, donde inicialmente primaba casi absolutamente el consentimiento implicado para pasar al informado de pacientes y familiares. Además se incrementó en la medida de lo posible la participación de los pacientes graves y familiares en el proceso asistencial. Las  enfermedades cardiovasculares agudas fueron las situaciones clínicas que permitieron más autonomía en el consentimiento informado, y la falla múltiple de órganos donde el consentimiento implicado predominó

Has Selection for Improved Agronomic Traits Made Reed Canarygrass Invasive?

Plant breeders have played an essential role in improving agricultural crops, and their efforts will be critical to meet the increasing demand for cellulosic bioenergy feedstocks. However, a major concern is the potential development of novel invasive species that result from breeders' efforts to improve agronomic traits in a crop. We use reed canarygrass as a case study to evaluate the potential of plant breeding to give rise to invasive species. Reed canarygrass has been improved by breeders for use as a forage crop, but it is unclear whether breeding efforts have given rise to more vigorous populations of the species. We evaluated cultivars, European wild, and North American invader populations in upland and wetland environments to identify differences in vigor between the groups of populations. While cultivars were among the most vigorous populations in an agricultural environment (upland soils with nitrogen addition), there were no differences in above- or below-ground production between any populations in wetland environments. These results suggest that breeding has only marginally increased vigor in upland environments and that these gains are not maintained in wetland environments. Breeding focuses on selection for improvements of a specific target population of environments, and stability across a wide range of environments has proved elusive for even the most intensively bred crops. We conclude that breeding efforts are not responsible for wetland invasion by reed canarygrass and offer guidelines that will help reduce the possibility of breeding programs releasing cultivars that will become invasive

CLIPR-59 regulates TNF-α-induced apoptosis by controlling ubiquitination of RIP1

Tumor necrosis factor-α (TNF-α) has important roles in several immunological events by regulating apoptosis and transcriptional activation of cytokine genes. Intracellular signaling mediated by TNF-receptor-type 1 (TNFR1) is constituted by two sequential protein complexes: Complex-I containing the receptor and Complex-II-containing Caspase-8. Protein modifications, particularly ubiquitination, are associated with the regulation of the formation of these complexes. However, the underlying mechanisms remain poorly defined. Here, we identified CLIP-170-related 59 kDa protein (CLIPR-59) as a novel adaptor protein for TNFR1. Experimental reduction of CLIPR-59 levels prevented induction of apoptosis and activation of caspases in the context of TNF-α signaling. CLIPR-59 binds TNFR1 but dissociates in response to TNF-α stimulation. However, CLIPR-59 is also involved in and needed for the formation of Complex-II. Moreover, CLIPR-59 regulates TNF-α-induced ubiquitination of receptor-interacting protein 1 (RIP1) by its association with CYLD, a de-ubiquitinating enzyme. These findings suggest that CLIPR-59 modulates ubiquitination of RIP1, resulting in the formation of Complex-II and thus promoting Caspase-8 activation to induce apoptosis by TNF-α

Geographic distribution at subspecies resolution level: closely related Rhodopirellula species in European coastal sediments.

Members of the marine genus Rhodopirellula are attached living bacteria and studies based on cultured Rhodopirellula strains suggested that three closely related species R. baltica, 'R. europaea' and 'R. islandica' have a limited geographic distribution in Europe. To address this hypothesis, we developed a nested PCR for a single gene copy detection of a partial acetyl CoA synthetase (acsA) from intertidal sediments collected all around Europe. Furthermore, we performed growth experiments in a range of temperature, salinity and light conditions. A combination of Basic Local Alignment Search Tool (BLAST) and Minimum Entropy Decomposition (MED) was used to analyze the sequences with the aim to explore the geographical distribution of the species and subspecies. MED has been mainly used for the analysis of the 16S rRNA gene and here we propose a protocol for the analysis of protein-coding genes taking into account the degeneracy of the codons and a possible overestimation of functional diversity. The high-resolution analysis revealed differences in the intraspecies community structure in different geographic regions. However, we found all three species present in all regions sampled and in agreement with growth experiments we demonstrated that Rhodopirellula species do not have a limited geographic distribution in Europe

Time since Introduction, Seed Mass, and Genome Size Predict Successful Invaders among the Cultivated Vascular Plants of Hawaii

Extensive economic and environmental damage has been caused by invasive exotic plant species in many ecosystems worldwide. Many comparative studies have therefore attempted to predict, from biological traits, which species among the pool of naturalized non-natives become invasive. However, few studies have investigated which species establish and/or become pests from the larger pool of introduced species and controlled for time since introduction. Here we present results from a study aimed at quantifying predicting three classes of invasive species cultivated in Hawaii. Of 7,866 ornamental species cultivated in Hawaii between 1840 and 1999, 420 (5.3%) species naturalized, 141 (1.8%) have been classified as weeds, and 39 (0.5%) were listed by the state of Hawaii as noxious. Of the 815 species introduced >80 years ago, 253 (31%) have naturalized, 90 (11%) are classed as weeds, and 22 (3%) as noxious by the state of Hawaii. Using boosted regression trees we classified each group with nearly 90% accuracy, despite incompleteness of data and the low proportion of naturalized or pest species. Key biological predictors were seed mass and highest chromosome number standardized by genus which, when data on residence time was removed, were able to predict all three groups with 76–82% accuracy. We conclude that, when focused on a single region, screening for potential weeds or noxious plants based on a small set of biological traits can be achieved with sufficient accuracy for policy and management purposes