441 research outputs found
Seasonality and stochastic trends in German consumption and income, 1960.1- 1987.4
The quarterly time series of German consumption and income are analyzed with respect to seasonality and stochastic trends. It emerges that both variables can be appropriately described by a periodically integrated autoregression. An implication is that the stochastic trend and the seasonal fluctuations are not independent for each of the univariate series. In order to test for cointegration across the two series, we propose several methods which take account of the relationship between seasons and trends in the univariate series. Some of these methods boil down to extracting the stochastic trend from the univariate series in a first step and to relating these trends using cointegration techniques in a second step. Another method is an extension of the Johansen cointegration testing approach to periodic vector autoregressions. Monte Carlo simulations are used to evaluate the empirical performance of the various methods. The main empirical result is that only in the first quarter there seems to be cointegration between German consumption and income
Shear sum rules at finite chemical potential
We derive sum rules which constrain the spectral density corresponding to the
retarded propagator of the T_{xy} component of the stress tensor for three
gravitational duals. The shear sum rule is obtained for the gravitational dual
of the N=4 Yang-Mills, theory of the M2-branes and M5-branes all at finite
chemical potential. We show that at finite chemical potential there are
additional terms in the sum rule which involve the chemical potential. These
modifications are shown to be due to the presence of scalars in the operator
product expansion of the stress tensor which have non-trivial vacuum
expectation values at finite chemical potential.Comment: The proof for the absence of branch cuts is corrected.Results
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Guidance for researchers wanting to link NHS data using non-consent approaches: a thematic analysis of feedback from the Health Research Authority Confidentiality Advisory Group
Introduction
The use of linked data and non-consent methodologies is a rapidly growing area of health research due to the increasing detail, availability and scope of routinely collected electronic health records data. However, gaining the necessary legal and governance approvals to undertake data linkage is a complex process in England.
Objectives
We reflect on our own experience of establishing lawful basis for data linkage through Section 251 approval, with the intention to build a knowledgebase of practical advice for future applicants.
Methods
Thematic analysis was conducted on a corpus of Section 251 feedback reports from the NHS Health Research Authority Confidentiality Advisory Group.
Results
Four themes emerged from the feedback. These were: (a) Patient and Public Involvement, (b)~Establishing Rationale, (c) Data maintenance and contingency, and the need to gain (d) Further Permissions from external authorities prior to full approval.
Conclusions
Securing Section 251 approval poses ethical, practical and governance challenges. However, through a comprehensive, planned approach Section 251 approval is possible, enabling researchers to unlock the potential of linked data for the purposes of health research
Sum rules and three point functions
Sum rules constraining the R-current spectral densities are derived
holographically for the case of D3-branes, M2-branes and M5-branes all at
finite chemical potentials. In each of the cases the sum rule relates a certain
integral of the spectral density over the frequency to terms which depend both
on long distance physics, hydrodynamics and short distance physics of the
theory. The terms which which depend on the short distance physics result from
the presence of certain chiral primaries in the OPE of two R-currents which are
turned on at finite chemical potential. Since these sum rules contain
information of the OPE they provide an alternate method to obtain the structure
constants of the two R-currents and the chiral primary. As a consistency check
we show that the 3 point function derived from the sum rule precisely matches
with that obtained using Witten diagrams.Comment: 41 page
Quarterly U.S. unemployment: cycles, seasons and asymmetries
This paper documents three stylized facts for the quarterly unemployment rate in the United States. Firstly, unemployment is asymmetric over the business cycle, i.e. it rises sharply in recessions and it falls slowly in expansions. Secondly, its seasonal fluctuations are not constant across the two business cycle stages in the sense that there is less seasonality in recession periods. Thirdly, the effect of shocks to the unemployment rate in expansions seem transitory, while this effect is permanent in recessions. Some implications of these stylized facts for empirical macroeconomics and seasonal adjustment are discussed
Posterior reversible encephalopathy syndrome in a child with cyclical vomiting and hypertension: a case report
<p>Abstract</p> <p>Introduction</p> <p>Posterior reversible encephalopathy syndrome is characterized by headache, nausea and vomiting, seizures and visual disturbances. It has certain characteristic radiological features, which allow diagnosis in the appropriate clinical setting and enable appropriate clinical therapy to be instituted.</p> <p>Case presentation</p> <p>A 10-year-old Caucasian girl who was hospitalized due to recurrent vomiting was diagnosed as having posterior reversible encephalopathy syndrome after an initial diagnosis of cyclical vomiting and hypertension was made.</p> <p>Conclusion</p> <p>Posterior reversible encephalopathy syndrome is a rare disorder in children. Early recognition of characteristic radiological features is key to the diagnosis as clinical symptoms may be non-specific or mimic other neurological illnesses. To the best of our knowledge this is the first case to report an association between posterior reversible encephalopathy syndrome, cyclical vomiting and hypertension. Furthermore, in this case, the resolution of the abnormalities found on magnetic resonance imaging over time did not appear to equate with clinical recovery.</p
Conclusions: reducing Burglary – summing Up
This book presented original and innovative research which has direct practical and policy implications for burglary security. The concluding chapter provides a synthesis of the research evidence discussed in the previous chapters addressing three broad themes: burglary trends and patterns; which security devices work and how; and burglary prevention lessons. The chapter ends with suggestions for future research
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Metal complexes of flavonoids: their synthesis, characterization, and enhanced anti-oxidant and anti-cancer activities
Flavonoids are polyphenolic compounds of natural origin. They are extensively studied within drug discovery programmes due to their wide ranging biological activities such as anti-microbial, anti-oxidant, anti-tumor, neuroprotective and cardioprotective properties. The ability of flavonoids to coordinate with metal atoms has provided new leads for drug discovery programmes, with better pharmacological activities and clinical profiles than the parent flavonoids. In this review, the enhanced anti-oxidant and anti-cancer activities of flavonoid metal complexes versus the parent flavonoids are discussed. Possible mechanisms of action for the metal complexes, such as DNA binding and apoptosis induction, are also presented alongside an overview of the synthesis of the metal complexes, and the different techniques used for their characterization
Somatic diseases in patients with schizophrenia in general practice: their prevalence and health care
BACKGROUND: Schizophrenia patients frequently develop somatic co-morbidity. Core tasks for GPs are the prevention and diagnosis of somatic diseases and the provision of care for patients with chronic diseases. Schizophrenia patients experience difficulties in recognizing and coping with their physical problems; however GPs have neither specific management policies nor guidelines for the diagnosis and treatment of somatic co-morbidity in schizophrenia patients. This paper systematically reviews the prevalence and treatment of somatic co-morbidity in schizophrenia patients in general practice. METHODS: The MEDLINE, EMBASE, PsycINFO data-bases and the Cochrane Library were searched and original research articles on somatic diseases of schizophrenia patients and their treatment in the primary care setting were selected. RESULTS: The results of this search show that the incidence of a wide range of diseases, such as diabetes mellitus, the metabolic syndrome, coronary heart diseases, and COPD is significantly higher in schizophrenia patients than in the normal population. The health of schizophrenic patients is less than optimal in several areas, partly due to their inadequate help-seeking behaviour. Current GP management of such patients appears not to take this fact into account. However, when schizophrenic patients seek the GP's help, they value the care provided. CONCLUSION: Schizophrenia patients are at risk of undetected somatic co-morbidity. They present physical complaints at a late, more serious stage. GPs should take this into account by adopting proactive behaviour. The development of a set of guidelines with a clear description of the GP's responsibilities would facilitate the desired changes in the management of somatic diseases in these patients
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