103 research outputs found
The Fermi surface of CeCoIn5: dHvA
Measurements of the de Haas - van Alphen effect in the normal state of the
heavy Fermion superconductor CeCoIn5 have been carried out using a torque
cantilever at temperatures ranging from 20 to 500 mK and in fields up to 18
tesla. Angular dependent measurements of the extremal Fermi surface areas
reveal a more extreme two dimensional sheet than is found in either CeRhIn5 or
CeIrIn5. The effective masses of the measured frequencies range from 9 to 20
m*/m0.Comment: 4 pages, 2 figures, submitted to PRB Rapid
Anomalous Superconducting Properties and Field Induced Magnetism in CeCoIn5
In the heavy fermion superconductor CeCoIn5 (Tc=2.3K) the critical field is
large, anisotropic and displays hysteresis. The magnitude of the critical-field
anisotropy in the a-c plane can be as large as 70 kOe and depends on
orientation. Critical field measurements in the (110) plane suggest 2D
superconductivity, whereas conventional effective mass anisotropy is observed
in the (100) plane. Two distinct field-induced magnetic phases are observed: Ha
appears deep in the superconducting phase, while Hb intersects Hc2 at T=1.4 K
and extends well above Tc. These observations suggest the possible realization
of a direct transition from ferromagnetism to Fulde-Ferrel-Larkin-Ovchinnikov
superconductivity in CeCoIn5.Comment: 4 pages, 3 figure
Inspiring and Aspiring Educators: An Intersection of Historic and Current Education Landscapes
The book Inspiring and Aspiring Educators: An Intersection of Historic and Current Education Landscapes is a collection of graduate student writings from the 2021 summer Education Doctorate Residency at Winona State University.https://openriver.winona.edu/educationeddbooks/1002/thumbnail.jp
New Aspects of the Temperature-Magnetic Field Phase Diagram of CeB6
We have measured the magnetic field dependence of the paramagnetic to the
field-induced high temperature antiferroquadrupolar magnetically ordered phase
transition is CeB6 from 0 to 60 T using a variety of techniques. It is found
that the field-dependent phase separation line becomes re-entrant above 35 T
and below 10 K. Measurements of resonant ultra-sound, specific heat and neutron
diffraction show conclusively that the zero-field temperature-dependent phase
transition is to a state with no ordered dipole moments, but with second order
transition signatures in both sound attenuation and specific heat.Comment: 4 pages, 4 figures, 11 references, submitted to Physical Review
Letter
Systemic Biomarkers of Neutrophilic Inflammation, Tissue Injury and Repair in COPD Patients with Differing Levels of Disease Severity
The identification and validation of biomarkers to support the assessment of novel therapeutics for COPD continues to be an important area of research. The aim of the current study was to identify systemic protein biomarkers correlated with measures of COPD severity, as well as specific protein signatures associated with comorbidities such as metabolic syndrome. 142 protein analytes were measured in serum of 140 patients with stable COPD, 15 smokers without COPD and 30 non-smoking controls. Seven analytes (sRAGE, EN-RAGE, NGAL, Fibrinogen, MPO, TGF-α and HB-EGF) showed significant differences between severe/very severe COPD, mild/moderate COPD, smoking and non-smoking control groups. Within the COPD subjects, univariate and multivariate analyses identified analytes significantly associated with FEV1, FEV1/FVC and DLCO. Most notably, a set of 5 analytes (HB-EGF, Fibrinogen, MCP-4, sRAGE and Sortilin) predicted 21% of the variability in DLCO values. To determine common functions/pathways, analytes were clustered in a correlation network by similarity of expression profile. While analytes related to neutrophil function (EN-RAGE, NGAL, MPO) grouped together to form a cluster associated with FEV1 related parameters, analytes related to the EGFR pathway (HB-EGF, TGF-α) formed another cluster associated with both DLCO and FEV1 related parameters. Associations of Fibrinogen with DLCO and MPO with FEV1/FVC were stronger in patients without metabolic syndrome (r = −0.52, p = 0.005 and r = −0.61, p = 0.023, respectively) compared to patients with coexisting metabolic syndrome (r = −0.25, p = 0.47 and r = −0.15, p = 0.96, respectively), and may be driving overall associations in the general cohort. In summary, our study has identified known and novel serum protein biomarkers and has demonstrated specific associations with COPD disease severity, FEV1, FEV1/FVC and DLCO. These data highlight systemic inflammatory pathways, neutrophil activation and epithelial tissue injury/repair processes as key pathways associated with COPD
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