Hypopharyngeal tumors-SCC - case presentation

Hypopharyngeal carcinoma is relatively uncommon representing only 10% of all proximal aerodigestive track malignancies. Unfortunately hypopharyngeal tumours produce few symptoms until they are advanced. Treatment of hypopharyngeal squamous cell carcinoma usually involves surgical resection and/or chemo-radiotherapy. We are presenting a case MW, 68 years old 0+, ex smoker and alcohol abuse, with a 5 weeks history of dysphagia and haematemasis. Patient was diagnosed with Hypopharingeal SCC and treated surgicaly-ENT and oncologicaly. Squamous cell carcinoma of the hypopharynx carries the worst prognosis of any SCC of the upper aerodigestive tract of the head and neck both because it often presents with advanced disease. Even when prognosis is corrected for stage, hypopharyngeal cancers continue to have poor outcomes.Der Erstautor gibt keinen Interessenkonflikt an

Hearing loss - non genetic etiology of newborns diagnosed in Neonatal Intensive Care Unit

Objectives: The purpose of this study is to assess the newborns hospitalized in The Neonatal Intensive Care Unit Emergency County Clinical Hospital Oradea with positive screening for hearing loss and to identify non-genetic causes of the hearing loss.Materials and Methods: This prospective study was presented in NICU in the period January 2008 to June 2012, on a number of 139 newborns with positive screening for hearing loss at the second test (AABR+TEOAE). Were excluded from the study newborns with genetic etiology for hearing loss ( craniofacial anomalies, genetic syndromes and family history for hearing loss). Therefore, 126 patients with positive screening for hearing loss were evaluated. Every patient was evaluated according to the data provided by the Declaration of principles and guidelines for detection and early intervention for hearing loss at newborns, issued by The Joint Committee on Infant Hearing in 2007. All infants identified with congenital and postnatal infections were evaluated clinically and paraclinical by serological laboratory examination, through ophtalmological examination and transfontanelar ultrasound. Results: Of the 126 newborns with positive screening for hearing loss 12 patients were from positive mothers for TORCH test. 50% of intrauterine infections were given by CMV, followed by herpes simplex, toxoplasma and rubella. Conclusions: Diagnosis of hearing loss was found in 3,17% of infants hospitalized in NICU with positive screening for hearing loss, respectively 2 patients with cytomegalovirus infection, one with toxoplasmosis and one with congenital rubella, which corresponds to the statistical data from the literature: 2 - 4 / 100 newborns.Keywords: newborn, hearing screening, sensorineural hearing loss, TORCH.Der Erstautor gibt keinen Interessenkonflikt an