Evaluation of eczema, asthma, allergic rhinitis and allergies among the Grade-1 children of Iqaluit

Additional file 3: Appendix S3. Tested allergens

Critical Importance of Standardized Nomenclature and Classification in Venous Surgery and Interventional Treatments

In this chapter the authors explain the need for standardization of nomenclature and classification of deep venous disease in patients selected for venous surgery and/or (minimally invasive) interventional treatment. For both acute deep vein obstruction (deep vein thrombosis) and chronic deep vein obstruction (deep vein stenosis or occlusion), the concept behind treatment selection and classification of disease is explained and illustrated with figures.keywordsinferior vena cavavaricose veiniliac veinvenous diseasevenous insufficiencythese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves

Effects of Specific Multi-Nutrient Enriched Diets on Cerebral Metabolism, Cognition and Neuropathology in AbetaPPswe-PS1dE9 Mice

Contains fulltext : 119269.pdf (publisher's version ) (Open Access)Recent studies have focused on the use of multi-nutrient dietary interventions in search of alternatives for the treatment and prevention of Alzheimer's disease (AD). In this study we investigated to which extent long-term consumption of two specific multi-nutrient diets can modulate AD-related etiopathogenic mechanisms and behavior in 11-12-month-old AbetaPPswe-PS1dE9 mice. Starting from 2 months of age, male AbetaPP-PS1 mice and wild-type littermates were fed either a control diet, the DHA+EPA+UMP (DEU) diet enriched with uridine monophosphate (UMP) and the omega-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), or the Fortasyn(R) Connect (FC) diet enriched with the DEU diet plus phospholipids, choline, folic acid, vitamins and antioxidants. We performed behavioral testing, proton magnetic resonance spectroscopy, immunohistochemistry, biochemical analyses and quantitative real-time PCR to gain a better understanding of the potential mechanisms by which these multi-nutrient diets exert protective properties against AD. Our results show that both diets were equally effective in changing brain fatty acid and cholesterol profiles. However, the diets differentially affected AD-related pathologies and behavioral measures, suggesting that the effectiveness of specific nutrients may depend on the dietary context in which they are provided. The FC diet was more effective than the DEU diet in counteracting neurodegenerative aspects of AD and enhancing processes involved in neuronal maintenance and repair. Both diets elevated interleukin-1beta mRNA levels in AbetaPP-PS1 and wild-type mice. The FC diet additionally restored neurogenesis in AbetaPP-PS1 mice, decreased hippocampal levels of unbound choline-containing compounds in wild-type and AbetaPP-PS1 animals, suggesting diminished membrane turnover, and decreased anxiety-related behavior in the open field behavior. In conclusion, the current data indicate that specific multi-nutrient diets can influence AD-related etiopathogenic processes. Intervention with the FC diet might be of interest for several other neurodegenerative and neurological disorders