The interpretation of brain natriuretic peptide in critical care patients; will it ever be useful?

The measurement of B-type natriuretic peptide (BNP) is recommended for the diagnosis of decompensated heart failure, the prognosis of chronic heart failure is worse if BNP is increased and studies suggest that BNP is useful to guide therapy. A study by Di Somma and colleagues adds to the body of evidence showing that patients with a marked decrease in BNP concentrations during their hospital admission are less likely to be readmitted with a further adverse cardiac event than patients in whom BNP fails to decrease. However, the wider interpretation of BNP concentrations in critically ill patients with other conditions remains uncertain

Classical String in Curved Backgrounds

The Mathisson-Papapetrou method is originally used for derivation of the particle world line equation from the covariant conservation of its stress-energy tensor. We generalize this method to extended objects, such as a string. Without specifying the type of matter the string is made of, we obtain both the equations of motion and boundary conditions of the string. The world sheet equations turn out to be more general than the familiar minimal surface equations. In particular, they depend on the internal structure of the string. The relevant cases are classified by examining canonical forms of the effective 2-dimensional stress-energy tensor. The case of homogeneously distributed matter with the tension that equals its mass density is shown to define the familiar Nambu-Goto dynamics. The other three cases include physically relevant massive and massless strings, and unphysical tahyonic strings.Comment: 12 pages, REVTeX 4. Added a note and one referenc

Atmospheric effects on remote sensing of non-uniform temperature sources

The equations of transfer, for a plane-parallel scattering atmosphere with a point source of energy on the lower bounding surface, were solved for various values of sensor/point source orientation and optical depths. Applications of this analysis to Skylab and ERTS mission are discussed, and requirements for atmospheric property data and radiation transfer properties are considered

Canadian national sport organisations’ use of the web for relationship marketing in promoting sport participation

Sport participation development requires a systematic process which involves knowledge creation, dissemination and interactions between National Sport Organisations, participants, clubs and associations as well as other agencies. Using a relationship marketing approach (Grönroos, 1997, Gummesson, 2002, Olkkonen, 1999), this paper addressed the question ‘How do Canadian NSOs use the Web, in terms of functionality and services offered, to create and maintain relationships with sport participants and their sport delivery partners?’ Ten Canadian NSOs’ websites were examined: functionality was analysed using Burgess and Cooper’s (2000) eMICA model, while NSOs’ utilisation of the Internet to establish and maintain relationships with sport participants was analysed using Wang, Head and Archer’s (2000) relationship-building process model for the Web. It was found that Canadian NSOs were receptive to the use of the Web, but their information-gathering and dissemination activities, which make-up the relationship-building process, appear sparse, and in some cases are lagging behind the voluntary sector in the country

Speckle-visibility spectroscopy: A tool to study time-varying dynamics

We describe a multispeckle dynamic light scattering technique capable of resolving the motion of scattering sites in cases that this motion changes systematically with time. The method is based on the visibility of the speckle pattern formed by the scattered light as detected by a single exposure of a digital camera. Whereas previous multispeckle methods rely on correlations between images, here the connection with scattering site dynamics is made more simply in terms of the variance of intensity among the pixels of the camera for the specified exposure duration. The essence is that the speckle pattern is more visible, i.e. the variance of detected intensity levels is greater, when the dynamics of the scattering site motion is slow compared to the exposure time of the camera. The theory for analyzing the moments of the spatial intensity distribution in terms of the electric field autocorrelation is presented. It is demonstrated for two well-understood samples, a colloidal suspension of Brownian particles and a coarsening foam, where the dynamics can be treated as stationary. However, the method is particularly appropriate for samples in which the dynamics vary with time, either slowly or rapidly, limited only by the exposure time fidelity of the camera. Potential applications range from soft-glassy materials, to granular avalanches, to flowmetry of living tissue.Comment: review - theory and experimen

Metastasis of a transplantable mammary tumour in rats treated with cyclophosphamide and/or irradiation.

We report observations on the spread by metastasis and infiltration of a transplantable tumour in rats treated by 60Co gamma-irradiation of the primary, irradiation plus parenteral cyclophosphamide, or parenteral cyclophosphamide alone. The proportion of animals with overt disseminated disease and the extent of spread were measured with respect to the time elapsed after implantation and treatment of the primary tumour. The incidence of metastatic disease was broadly similar for all treatment groups, but the extent of dissemination was greater in rats whose treatment included cyclophosphamide

Closed String Tachyons on C/Z_N

We analyse the condensation of closed string tachyons on the $C/Z_N$ orbifold. We construct the potential for the tachyons upto the quartic interaction term in the large $N$ limit. In this limit there are near marginal tachyons. The quartic coupling for these tachyons is calculated by subtracting from the string theory amplitude for the tachyons, the contributions from the massless exchanges, computed from the effective field theory. We argue that higher point interaction terms are are also of the same order in 1/N as the quartic term and are necessary for existence of the minimum of the tachyon potential that is consistent with earlier analysis.Comment: 19 pages, 1 figure; comments added about $N$ dependence of contact ter