Ionic liquid promoted facile and green synthesis of 1,8-dioxo-octahydroxanthene derivatives under microwave irradiation

An efficient and environmentally benign procedure for the synthesis of 1,8-dioxo-octahydroxanthene by condensation reaction between 5,5-dimethyl-1,3-cyclohexanedione (dimedone) and structurally diverse aldehydes using carboxy functionalized ionic liquid under microwave irradiation is described. The methodology provides synergy of ionic liquid and microwave irradiation which offers several advantages such as high yields in shorter reaction time, convenient operation, reusability of catalyst and easy work-up

One-pot solvent-free rapid and green synthesis of 3,4-dihydropyrano[c]chromenes using grindstone chemistry

An easy solvent-free method is described for the synthesis of 3,4-dihydropyrano[c]chromenes by a one pot three component coupling reaction of aromatic aldehydes, malononitrile, and 4-hydroxycoumarin using basic ionic liquid as the catalyst by grindstone chemistry. The salient features of this one pot protocol are short reaction times, cleaner reaction profiles and simple workup

Polymer supported sulphanilic acid – A novel green heterogeneous catalyst for synthesis of benzimidazole derivatives

Polymer supported sulphanilic acid was synthesized and used as green, reusable and heterogeneous catalyst and duly characterized using chemical methods like determination of free hydroxyl content, epoxy equivalent weight and free sulphonic acid content as well as infrared spectroscopy and thermogravimetric analysis. The prepared catalyst was applied for one-pot synthesis of 2-substituted benzimidazoles from o-phenylenediamine and various aromatic aldehydes in absolute ethanol under thermal condition. Catalyst was separated from the product by simple filtration and could be reused for at least five times with almost retention in its efficiency. Due to three dimensional network structures, it shows high thermal stability and can be reused without any further purification

Oxidative cyanide-free cyanation on arylboronic acid derivatives using aryl/heteroaryl thiocyanate using novel IL-PdCl₄ catalyst under mild condition

<p>An efficient and simple method is reported for the cyanation on arylboronic acid using various simple/indole thiocyanates using a new IL-PdCl₄ catalyst. The cascade process involves a coupling reaction without any additive to give a wide range of cyanide derivatives. Cyanation on various arylboronic acids underwent smoothly affording the corresponding arylnitriles in good to high yields.</p