3,818 research outputs found
Human Rights and English Revolution
Durante mucho tiempo se ha mantenido que el desarrollo de la cultura legal, política y social de respeto de los derechos humanos en Inglaterra y en el mundo Anglófono se originó en el siglo diecisiete, el siglo de la Revolución inglesa. Este trabajo cuestiona la idea de que hubo un discurso de derechos humanos, en el sentido de derechos que se abstraían de lugares, circunstancias y categorías sociales y que se asociaban a individuos qua individuos, durante ese periodo. Por el contrario, se sugiere que el desarrollo de dicho discurso se impedía porque se enfatizaban los derechos colectivos antes que los individuales; tanto la limitación legal de los derechos personales como la de los poderes ejecutivos de gobierno; los deberes antes que los derechos; y los imperativos religiosos además de los imperativos constitucionales.The development ofa legal, political and social culture ofrespect for human rights in England, and from thence in the Anglophone world, has long been held to have its origins in the seventeenth century, the century of the English Revolution. This essay challenges the perception that there was a discourse of human rights, in the sense of rights abstracted from particular places, circumstances and social categories and associated with individuals qua individuals, in this periodo Instead, it is suggested that the development of a discourse of human rights was impeded by an emphasis on collective, rather than individual, rights; on the legal limitation of personal rights as well as the executive powers of government; on duty rather than rights; and on religious as well as constitutional imperatives.Publicad
Range Grasses of Hawaii
This bulletin discusses the more important grasses growing on local ranges, their growth in other parts of the world, nature of growth, palatability, persistence, climatic requirements, and present importance and possibilities for Hawaii
Safety and tolerability of NXY-059 for acute intracerebral hemorrhage: the CHANT trial
<p><b>Background and Purpose:</b> NXY-059 is a free radical-trapping neuroprotectant developed for use in acute ischemic stroke. To facilitate prompt administration of treatment, potentially before neuroimaging, we investigated the safety of NXY-059 in patients with intracerebral hemorrhage (ICH).</p>
<p><b>Methods:</b> We randomized 607 patients within 6 hours of acute ICH to receive 2270 mg intravenous NXY-059 over 1 hour and then up to 960 mg/h over 71 hours, or matching placebo, in addition to standard care. The primary outcome was safety: the mortality and the frequency of adverse events, and the change from baseline for a variety of serum, imaging, and electrophysiological measurements. We also studied the overall distribution of disability scores on the modified Rankin Scale (mRS) and the Barthel index.</p>
<p><b>Results:</b> We treated 300 patients with NXY-059 and 303 with placebo. Treatment groups were well matched for prognostic variables including Glasgow Coma Scale, risk factors, and age. The mean National Institute of Health Stroke Scale score on admission was 14 in both groups. The baseline hemorrhage volume was 22.4±20.1 mL in the NXY-059 group and 23.3±22.8 mL in the placebo group (mean±SD). Most hemorrhages were related to hypertension or anticoagulant use. Mortality was similar in both groups: 20.3% for NXY-059 and 19.8% for placebo-treated patients. The proportion of patients who experienced an adverse event was the same for both groups, whereas for serious adverse events the proportion was slightly higher in the NXY-059 group. However, no pattern emerged to indicate a safety concern. Serum potassium fell transiently in both groups, lower in the NXY-059 group. There were no differences in 3-month function, disability, or neurological deficit scores. The odds ratio for an improved outcome in 3-month mRS scores in the NXY-059 group was 1.01 (95% CI 0.75, 1.35).</p>
<p><b>Conclusions:</b> NXY-059 given within 6 hours of acute ICH has a good safety and tolerability profile, with no adverse effect on important clinical outcomes.</p>
Polarized Dirac fermions in de Sitter spacetime
The tetrad gauge invariant theory of the free Dirac field in two special
moving charts of the de Sitter spacetime is investigated pointing out the
operators that commute with the Dirac one. These are the generators of the
symmetry transformations corresponding to isometries that give rise to
conserved quantities according to the Noether theorem. With their help the
plane wave spinor solutions of the Dirac equation with given momentum and
helicity are derived and the final form of the quantum Dirac field is
established. It is shown that the canonical quantization leads to a correct
physical interpretation of the massive or massless fermion quantum fields.Comment: 19 pages, LaTeX w AMS sym
Shoshonites in southern Tibet record Late Jurassic rifting of a Tethyan intraoceanic island arc
Detailed field mapping combined with a petrologic and geochemical investigation of the Zedong terrane within the Yarlung Tsangpo suture zone provides insights to the evolution of now mostly subducted portions of Tethys during the Late Jurassic. The terrane is dominated by volcanic rocks of shoshonitic affinity, which were erupted in a submarine oceanic island arc setting. The volcanic island arc was built on a basement of oceanic crust, and the shoshonites locally overlie a thin section of pillowed island arc tholeiites and red ribbon-bedded radiolarian cherts. Geochemistry of the shoshonites suggests that their development occurred in a setting analogous to that of Late Miocene to Early Pliocene Fiji and was associated with an arc rifting. We speculate that this event may have been a far-field response to developments associated with Gondwana breakup
Microfluidic and Nanofluidic Cavities for Quantum Fluids Experiments
The union of quantum fluids research with nanoscience is rich with
opportunities for new physics. The relevant length scales in quantum fluids,
3He in particular, are comparable to those possible using microfluidic and
nanofluidic devices. In this article, we will briefly review how the physics of
quantum fluids depends strongly on confinement on the microscale and nanoscale.
Then we present devices fabricated specifically for quantum fluids research,
with cavity sizes ranging from 30 nm to 11 microns deep, and the
characterization of these devices for low temperature quantum fluids
experiments.Comment: 12 pages, 3 figures, Accepted to Journal of Low Temperature Physic
Smooth vortex precession in superfluid 4He
We have measured a precessing superfluid vortex line, stretched from a wire
to the wall of a cylindrical cell. By contrast to previous experiments with a
similar geometry, the motion along the wall is smooth. The key difference is
probably that our wire is substantially off center. We verify several numerical
predictions about the motion, including an asymmetry in the precession
signature, the behavior of pinning events, and the temperature dependence of
the precession.Comment: 8 pages, 8 figure
First-principles extrapolation method for accurate CO adsorption energies on metal surfaces
We show that a simple first-principles correction based on the difference
between the singlet-triplet CO excitation energy values obtained by DFT and
high-level quantum chemistry methods yields accurate CO adsorption properties
on a variety of metal surfaces.
We demonstrate a linear relationship between the CO adsorption energy and the
CO singlet-triplet splitting, similar to the linear dependence of CO adsorption
energy on the energy of the CO 2* orbital found recently {[Kresse {\em et
al.}, Physical Review B {\bf 68}, 073401 (2003)]}. Converged DFT calculations
underestimate the CO singlet-triplet excitation energy ,
whereas coupled-cluster and CI calculations reproduce the experimental . The dependence of on is used
to extrapolate for the top, bridge and hollow sites for the
(100) and (111) surfaces of Pt, Rh, Pd and Cu to the values that correspond to
the coupled-cluster and CI value. The correction
reproduces experimental adsorption site preference for all cases and obtains
in excellent agreement with experimental results.Comment: Table sent as table1.eps. 3 figure
Induction of c-Jun immunoreactivity in spinal cord and brainstem neurons in a transgenic mouse model for amyotrophic lateral sclerosis
Transgenic mice carrying amyotrophic lateral sclerosis (ALS)-linked superoxide dismutase 1 (SOD1) mutations develop a motoneuron disease resembling human ALS. c-Jun is a transcription factor frequently induced in injured neurons. In this study we have examined the distribution of c-Jun-immunoreactivity in the brainstem and spinal cord of transgenic SOD1 mice with a glycine 93 alanine (G93A) mutation. In non-transgenic littermates c-Jun immunostaining was predominantly situated in motoneurons. The number of c-Jun immunoreactive motoneuron was reduced in SOD1(G93A) mice due to pronounced loss of motoneurons. In SOD1(G93A) mice, however, c-Jun-immunoreactivity was strongly induced in neurons in the intermediate zone (Rexed's laminae V-VIII and X) of the spinal cord and throughout the brainstem reticular formation. These findings are of interest since increased levels of c-jun also have been found in the intermediate zone of the spinal cord of ALS patients. Thus c-Jun may be involved in the neurodegenerative processes both in ALS and in motoneuron disease in SOD1(G93A) mice
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