1,837 research outputs found

    Team QCRI-MIT at SemEval-2019 Task 4: Propaganda Analysis Meets Hyperpartisan News Detection

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    In this paper, we describe our submission to SemEval-2019 Task 4 on Hyperpartisan News Detection. Our system relies on a variety of engineered features originally used to detect propaganda. This is based on the assumption that biased messages are propagandistic in the sense that they promote a particular political cause or viewpoint. We trained a logistic regression model with features ranging from simple bag-of-words to vocabulary richness and text readability features. Our system achieved 72.9% accuracy on the test data that is annotated manually and 60.8% on the test data that is annotated with distant supervision. Additional experiments showed that significant performance improvements can be achieved with better feature pre-processing.Comment: Hyperpartisanship, propaganda, news media, fake news, SemEval-201

    Introduction: Currents, Cross-Currents, Undercurrents

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    The similarities in an issue such as this one are often purely serendipitous; JASAL 10 brings together work submitted to a general, non-thematic issue and it should not surprise that the range of material is very diverse. Yet on occasion there are obvious points of contact between the various pieces and that is certainly the case here. The subtitle we have given to this brief Introduction seeks to capture some of the ways in which the essays interrelate, both complementing (and supplementing) each other and complicating particular readings. Essays included here range from critical examinations of well-known works, as is the case with Odette Kelada’s reading of Kate Grenville’s The Secret River, David Fonteyn’s and Kerry Leves’ respective engagement with Randolph Stow’s work, and Michael Farrell’s energetic take on A.B. Banjo Paterson’s ‘Waltzing Matilda,’ to Ian Herbertson’s discussion of lesser known work such as Criena Rohan’s The Delinquents and Mudrooroo’s Wild Cat Falling and Paul Sharrad’s comprehensive survey of Aust Lit.’s expansion into cultural and political spaces broadly defined as ‘Asia’

    AGB Variables and the Mira Period-Luminosity Relation

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    Published data for large amplitude asymptotic giant branch variables in the Large Magellanic Cloud are re-analysed to establish the constants for an infrared (K) period-luminosity relation of the form: Mk=rho[log P-2.38] + delta. A slope of rho=-3.51+/-0.20 and a zero point of delta=-7.15+/-0.06 are found for oxygen-rich Miras (if a distance modulus of 18.39+/-0.05 is used for the LMC). Assuming this slope is applicable to Galactic Miras we discuss the zero-point for these stars using the revised Hipparcos parallaxes together with published VLBI parallaxes for OH Masers and Miras in Globular Clusters. These result in a mean zero-point of delta=-7.25+/-0.07 for O-rich Galactic Miras. The zero-point for Miras in the Galactic Bulge is not significantly different from this value. Carbon-rich stars are also discussed and provide results that are consistent with the above numbers, but with higher uncertainties. Within the uncertainties there is no evidence for a significant difference between the period-luminosity relation zero-points for systems with different metallicity.Comment: 15 pages, 3 figures, accepted for MNRA

    Cost of Salmonella infections in Australia, 2015

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    Copyright Ó, International Association for Food Protection Gastroenteritis caused from infections with Salmonella enterica (salmonellosis) causes significant morbidity in Australia. In addition to acute gastroenteritis, approximately 8.8% of people develop irritable bowel syndrome (IBS) and 8.5% of people develop reactive arthritis (ReA). We estimated the economic cost of salmonellosis and associated sequel illnesses in Australia in a typical year circa 2015. We estimated incidence, hospitalizations, other health care usage, absenteeism, and premature mortality for four age groups using a variety of complementary data sets. We calculated direct costs (health care) and indirect costs (lost productivity and premature mortality) by using Monte Carlo simulation to estimate 90% credible intervals (CrI) around our point estimates. We estimated that 90,833 cases, 4,312 hospitalizations, and 19 deaths occurred from salmonellosis in Australia circa 2015 at a direct cost of AUD 23.8 million (90% CrI, 19.3 to 28.9 million) and a total cost of AUD 124.4 million (90% CrI, 107.4 to 143.1 million). When IBS and ReA were included, the estimated direct cost was 35.7 million (90% CrI, 29.9 to 42.7 million) and the total cost was AUD 146.8 million (90% CrI, 127.8 to 167.9 million). Foodborne infections were responsible for AUD 88.9 million (90% CrI, 63.9 to 112.4 million) from acute salmonellosis and AUD 104.8 million (90% CrI, 75.5 to 132.3 million) when IBS and ReA were included. Targeted interventions to prevent illness could considerably reduce costs and societal impact from Salmonella infections and sequel illnesses in Australia

    TGF-b2 induction regulates invasiveness of theileria-transformed leukocytes and disease susceptibility

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    Theileria parasites invade and transform bovine leukocytes causing either East Coast fever (T. parva), or tropical theileriosis (T. annulata). Susceptible animals usually die within weeks of infection, but indigenous infected cattle show markedly reduced pathology, suggesting that host genetic factors may cause disease susceptibility. Attenuated live vaccines are widely used to control tropical theileriosis and attenuation is associated with reduced invasiveness of infected macrophages in vitro. Disease pathogenesis is therefore linked to aggressive invasiveness, rather than uncontrolled proliferation of Theileria-infected leukocytes. We show that the invasive potential of Theileria-transformed leukocytes involves TGF-b signalling. Attenuated live vaccine lines express reduced TGF-b2 and their invasiveness can be rescued with exogenous TGF-b. Importantly, infected macrophages from disease susceptible Holstein-Friesian (HF) cows express more TGF-b2 and traverse Matrigel with great efficiency compared to those from disease-resistant Sahiwal cattle. Thus, TGF-b2 levels correlate with disease susceptibility. Using fluorescence and time-lapse video microscopy we show that Theileria-infected, disease-susceptible HF macrophages exhibit increased actin dynamics in their lamellipodia and podosomal adhesion structures and develop more membrane blebs. TGF-b2-associated invasiveness in HF macrophages has a transcription-independent element that relies on cytoskeleton remodelling via activation of Rho kinase (ROCK). We propose that a TGF-b autocrine loop confers an amoeboid-like motility on Theileria-infected leukocytes, which combines with MMP-dependent motility to drive invasiveness and virulence

    Increased levels of a pro-inflammatory IgG receptor in the midbrain of people with schizophrenia

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    Background: There is growing evidence that neuroinflammation may contribute to schizophrenia neuropathology. Elevated pro-inflammatory cytokines are evident in the midbrain from schizophrenia subjects, findings that are driven by a subgroup of patients, characterised as a “high inflammation” biotype. Cytokines trigger the release of antibodies, of which immunoglobulin G (IgG) is the most common. The level and function of IgG is regulated by its transporter (FcGRT) and by pro-inflammatory IgG receptors (including FcGR3A) in balance with the anti-inflammatory IgG receptor FcGR2B. Testing whether abnormalities in IgG activity contribute to the neuroinflammatory abnormalities schizophrenia patients, particularly those with elevated cytokines, may help identify novel treatment targets. Methods: Post-mortem midbrain tissue from healthy controls and schizophrenia cases (n = 58 total) was used to determine the localisation and abundance of IgG and IgG transporters and receptors in the midbrain of healthy controls and schizophrenia patients. Protein levels of IgG and FcGRT were quantified using western blot, and gene transcript levels of FcGRT, FcGR3A and FcGR2B were assessed using qPCR. The distribution of IgG in the midbrain was assessed using immunohistochemistry and immunofluorescence. Results were compared between diagnostic (schizophrenia vs control) and inflammatory (high vs low inflammation) groups. Results: We found that IgG and FcGRT protein abundance (relative to β-actin) was unchanged in people with schizophrenia compared with controls irrespective of inflammatory subtype. In contrast, FcGRT and FcGR3A mRNA levels were elevated in the midbrain from “high inflammation” schizophrenia cases (FcGRT; p = 0.02, FcGR3A; p < 0.0001) in comparison to low-inflammation patients and healthy controls, while FcGR2B mRNA levels were unchanged. IgG immunoreactivity was evident in the midbrain, and approximately 24% of all individuals (control subjects and schizophrenia cases) showed diffusion of IgG from blood vessels into the brain. However, the intensity and distribution of IgG was comparable across schizophrenia cases and control subjects. Conclusion: These findings suggest that an increase in the pro-inflammatory Fcγ receptor FcGR3A, rather than an overall increase in IgG levels, contribute to midbrain neuroinflammation in schizophrenia patients. However, more precise information about IgG-Fcγ receptor interactions is needed to determine their potential role in schizophrenia neuropathology

    Effect of chronic ethanol exposure on rat ventilatory responses to hypoxia and hypercapnia

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    OBJECTIVE: The effect of chronic ethanol exposure on chemoreflexes has not been extensively studied in experimental animals. Therefore, this study tested the hypothesis that known ethanol-induced autonomic, neuroendocrine and cardiovascular changes coincide with increased chemoreflex sensitivity, as indicated by increased ventilatory responses to hypoxia and hypercapnia. METHODS: Male Wistar rats were subjected to increasing ethanol concentrations in their drinking water (first week: 5% v/v, second week: 10% v/v, third and fourth weeks: 20% v/v). At the end of each week of ethanol exposure, ventilatory parameters were measured under basal conditions and in response to hypoxia (evaluation of peripheral chemoreflex sensitivity) and hypercapnia (evaluation of central chemoreflex sensitivity). RESULTS: Decreased respiratory frequency was observed in rats exposed to ethanol from the first until the fourth week, whereas minute ventilation remained unchanged. Moreover, we observed an increased tidal volume in the second through the fourth week of exposure. The minute ventilation responses to hypoxia were attenuated in the first through the third week but remained unchanged during the last week. The respiratory frequency responses to hypoxia in ethanol-exposed rats were attenuated in the second through the third week but remained unchanged in the first and fourth weeks. There was no significant change in tidal volume responses to hypoxia. With regard to hypercapnic responses, no significant changes in ventilatory parameters were observed. CONCLUSIONS: Our data are consistent with the notion that chronic ethanol exposure does not increase peripheral or central chemoreflex sensitivity

    Active gravitational mass and the invariant characterization of Reissner-Nordstrom spacetime

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    We analyse the concept of active gravitational mass for Reissner-Nordstrom spacetime in terms of scalar polynomial invariants and the Karlhede classification. We show that while the Kretschmann scalar does not produce the expected expression for the active gravitational mass, both scalar polynomial invariants formed from the Weyl tensor, and the Cartan scalars, do.Comment: 6 pages Latex, to appear in General Relativity and Gravitatio

    Responsibility loadings for dental services by general dentists

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    Extent: 6p.BACKGROUND: Responsibility loadings determine relative value units of dental services that translate services into a common scale of work effort. The aims of this paper were to elicit responsibility loadings for a subset of dental services and to relate responsibility loadings to ratings of importance of the components of responsibility. METHODS: Responsibility loadings and ratings of components of responsibility were collected using mailed questionnaires from a random sample of Australian private general practice dentists in 2007 (response rate = 77%). RESULTS: Median responsibility loadings were 1.25 for an initial oral examination and for a 3+-surface amalgam restoration, 1.50 for a simple extraction and for root canal obturation (single canal), and 1.75 for subgingival curettage (per quadrant). Across the five services coefficients from a multivariate logit model showed that ratings of importance of knowledge (0.34), dexterity (0.24), physical effort (0.28) and mental effort (0.48) were associated with responsibility loadings (P < 0.05). CONCLUSIONS: The elicited median responsibility loadings showed agreement with previous estimates indicating convergent validity. Components of responsibility were associated with loadings indicating that components can explain and predict responsibility aspects of dental service provision.David S. Brennan and A. John Spence
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