420 research outputs found
In situ tryptophan-like fluorometers: assessing turbidity and temperature effects for freshwater applications
Tryptophan-like fluorescence (TLF) is an indicator of human influence on water quality as TLF peaks are associated with the input of labile organic carbon (e.g. sewage or farm waste) and its microbial breakdown. Hence, real-time measurement of TLF could be particularly useful for monitoring water quality at a higher temporal resolution than available hitherto. However, current understanding of TLF quenching/interference is limited for field deployable sensors. We present results from a rigorous test of two commercially available submersible tryptophan fluorometers (ex _ 285, em _ 350). Temperature quenching and turbidity interference were quantified in the laboratory and compensation algorithms developed. Field trials were then undertaken involving: (i) an extended deployment (28 days) in a small urban stream; and, (ii) depth profiling of an urban multi-level borehole. TLF was inversely related to water temperature (regression slope range: _1.57 to _2.50). Sediment particle size was identified as an important control on the turbidity specific TLF response, with signal amplification apparent 200 NTU for clay particles. Compensation algorithms significantly improved agreement between in situ and laboratory readings for baseflow and storm conditions in the stream. For the groundwater trial, there was an excellent agreement between laboratory and raw in situ TLF; temperature compensation provided only a marginal improvement, and turbidity corrections were unnecessary. These findings highlight the potential utility of real time TLF monitoring for a range of environmental applications (e.g. tracing polluting sources and monitoring groundwater contamination). However, in situations where high/ variable suspended sediment loads or rapid changes in temperature are anticipated concurrent monitoring of turbidity and temperature is required and site specific calibration is recommended for long term, surface water monitoring
A Closed Class of Hydrodynamical Solutions for the Collective Excitations of a Bose-Einstein Condensate
A trajectory approach is taken to the hydrodynamical treatment of collective
excitations of a Bose-Einstein condensate in a harmonic trap. The excitations
induced by linear deformations of the trap are shown to constitute a broad
class of solutions that can be fully described by a simple nonlinear matrix
equation. An exact closed-form expression is obtained for the solution
describing the mode {n=0, m=2} in a cylindrically symmetric trap, and the
calculated amplitude-dependent frequency shift shows good agreement with the
experimental results of the JILA group.Comment: RevTex, 4 pages, 1 eps figure, identical to the published versio
Instability of a Bose-Einstein Condensate with Attractive Interaction
We study the stability of a Bose-Einstein condensate of harmonically trapped
atoms with negative scattering length, specifically lithium 7. Our method is to
solve the time-dependent nonlinear Schrodinger equation numerically. For an
isolated condensate, with no gain or loss, we find that the system is stable
(apart from quantum tunneling) if the particle number N is less than a critical
number N_c. For N > N_c, the system collapses to high-density clumps in a
region near the center of the trap. The time for the onset of collapse is on
the order of 1 trap period. Within numerical uncertainty, the results are
consistent with the formation of a "black hole" of infinite density
fluctuations, as predicted by Ueda and Huang. We obtain numerically N_c
approximately 1251. We then include gain-loss mechanisms, i.e., the gain of
atoms from a surrounding "thermal cloud", and the loss due to two- and
three-body collisions. The number N now oscillates in a steady state, with a
period of about 145 trap periods. We obtain N_c approximately 1260 as the
maximum value in the oscillations.Comment: Email correspondence to [email protected] ; 18 pages and 9 EPS
figures, using REVTeX and BoxedEPS macro
Boundary of two mixed Bose-Einstein condensates
The boundary of two mixed Bose-Einstein condensates interacting repulsively
was considered in the case of spatial separation at zero temperature.
Analytical expressions for density distribution of condensates were obtained by
solving two coupled nonlinear Gross-Pitaevskii equations in cases corresponding
weak and strong separation. These expressions allow to consider excitation
spectrum of a particle confined in the vicinity of the boundary as well as
surface waves associated with surface tension.Comment: 6 pages, 3 figures, submitted to Phys.Rev.
Mean-field analysis of collapsing and exploding Bose-Einstein condensates
The dynamics of collapsing and exploding trapped Bose-Einstein condensat es
caused by a sudden switch of interactions from repulsive to attractive a re
studied by numerically integrating the Gross-Pitaevskii equation with atomic
loss for an axially symmetric trap. We investigate the decay rate of
condensates and the phenomena of bursts and jets of atoms, and compare our
results with those of the experiments performed by E. A. Donley {\it et al.}
[Nature {\bf 412}, 295 (2001)]. Our study suggests that the condensate decay
and the burst production is due to local intermittent implosions in the
condensate, and that atomic clouds of bursts and jets are coherent. We also
predict nonlinear pattern formation caused by the density instability of
attractive condensates.Comment: 7 pages, 8 figures, axi-symmetric results are adde
Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency
A detailed understanding of the mechanisms that establish or maintain the latent reservoir of HIV will guide approaches to eliminate persistent infection. We used a cell line and primary cell models of HIV latency to investigate viral RNA (vRNA) expression and the role of the host transcriptome using single-cell approaches. Single-cell vRNA quantitation identified distinct populations of cells expressing various levels of vRNA, including completely silent populations. Strikingly, single-cell RNA-seq of latently infected primary cells demonstrated that HIV downregulation occurred in diverse transcriptomic environments but was significantly associated with expression of a specific set of cellular genes. In particular, latency was more frequent in cells expressing a transcriptional signature that included markers of naive and central memory T cells. These data reveal that expression of HIV proviruses within the latent reservoir are influenced by the host cell transcriptional program. Therapeutic modulation of these programs may reverse or enforce HIV latency. Bradley et al. use single-cell RNA-seq to analyze cellular gene expression in a primary cell model of HIV latency. They identify cellular genes that are differentially expressed in cells in which HIV becomes transcriptionally downregulated. These results suggest a relationship between HIV latency and the transcriptional environment of the host cell
In-situ velocity imaging of ultracold atoms using slow--light
The optical response of a moving medium suitably driven into a slow-light
propagation regime strongly depends on its velocity. This effect can be used to
devise a novel scheme for imaging ultraslow velocity fields. The scheme turns
out to be particularly amenable to study in-situ the dynamics of collective and
topological excitations of a trapped Bose-Einstein condensate. We illustrate
the advantages of using slow-light imaging specifically for sloshing
oscillations and bent vortices in a stirred condensate
A new photon recoil experiment: towards a determination of the fine structure constant
We report on progress towards a measurement of the fine structure constant to
an accuracy of or better by measuring the ratio of the
Planck constant to the mass of the cesium atom. Compared to similar
experiments, ours is improved in three significant ways: (i) simultaneous
conjugate interferometers, (ii) multi-photon Bragg diffraction between same
internal states, and (iii) an about 1000 fold reduction of laser phase noise to
-138 dBc/Hz. Combining that with a new method to simultaneously stabilize the
phases of four frequencies, we achieve 0.2 mrad effective phase noise at the
location of the atoms. In addition, we use active stabilization to suppress
systematic effects due to beam misalignment.Comment: 12 pages, 9 figure
Instabilities in a Two-Component, Species Conserving Condensate
We consider a system of two species of bosons of equal mass, with
interactions and for bosons of the same and different
species respectively. We present a rigorous proof -- valid when the Hamiltonian
does not include a species switching term -- showing that, when
, the ground state is fully "polarized" (consists of
atoms of one kind only). In the unpolarized phase the low energy excitation
spectrum corresponds to two linearly dispersing modes that are even a nd odd
under species exchange. The polarization instability is signaled by the vani
shing of the velocity of the odd modes.Comment: To appear in Phys. Rev.
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