Patient ethnicity and three psychiatric intensive care units compared: the Tompkins Acute Ward Study

Background: Psychiatric Care Units provide care to disturbed patients in a context of higher security and staffing levels. Although such units are numerous, few systematic comparisons have been made, and there are indications that ethnic minority groups may be over-represented. Aim: To compare the rates of adverse incidents and patterns of usage of three Psychiatric Intensive Care Units. Method: The study used a triangulation or multi-method design, bringing together data from official statistics, local audit and interviews conducted with staff. Results: Intensive care patients were more likely to be young, male, and suffering a psychotic disorder, as compared to general acute ward patients. Caribbean patients were twice as likely, and Asian patients half as likely, to receive intensive care (age, gender and diagnosis controlled). There were large differences in service levels, staffing, team functioning and adverse incidents between the three units. Various aspects of physical security were important in preventing absconds. Conclusions: More evaluative research is required in order to define effective service levels, and to explore the nature of the interaction between ethnicity and inpatient care provision during acute illness

Structural insights into the function of type VI secretion system TssA subunits.

The type VI secretion system (T6SS) is a multi-protein complex that injects bacterial effector proteins into target cells. It is composed of a cell membrane complex anchored to a contractile bacteriophage tail-like apparatus consisting of a sharpened tube that is ejected by the contraction of a sheath against a baseplate. We present structural and biochemical studies on TssA subunits from two different T6SSs that reveal radically different quaternary structures in comparison to the dodecameric E. coli TssA that arise from differences in their C-terminal sequences. Despite this, the different TssAs retain equivalent interactions with other components of the complex and position their highly conserved N-terminal ImpA_N domain at the same radius from the centre of the sheath as a result of their distinct domain architectures, which includes additional spacer domains and highly mobile interdomain linkers. Together, these variations allow these distinct TssAs to perform a similar function in the complex

A method for formalizing, analyzing, and verifying secure user interfaces

Abstract. We present a methodology for the formalization of humancomputer interaction under security aspects. As part of the methodology, we give formal semantics for the well-known GOMS methodology for user modeling, and we provide a formal definition of an important aspect of human-computer interaction security. We show how formal GOMS models can be augmented with formal models of (1) the application and (2) the user’s assumptions about the application. In combination, this allows the pervasive formal modeling of and reasoning about secure human-computer interaction. The method is illustrated by a simple eVoting example