856 research outputs found
Direct detection of neutralino dark matter in supergravity
The direct detection of neutralino dark matter is analysed in general
supergravity scenarios, where non-universal soft scalar and gaugino masses can
be present. In particular, the theoretical predictions for the
neutralino-nucleon cross section are studied and compared with the sensitivity
of dark matter detectors. We take into account the most recent astrophysical
and experimental constraints on the parameter space, including the current
limit on B(Bs-> mu+ mu-). The latter puts severe limitations on the dark matter
scattering cross section, ruling out most of the regions that would be within
the reach of present experiments. We show how this constraint can be softened
with the help of appropriate choices of non-universal parameters which increase
the Higgsino composition of the lightest neutralino and minimise the chargino
contribution to the b->s transition.Comment: 27 pages, 22 figure
Supersymmetric Benchmarks with Non-Universal Scalar Masses or Gravitino Dark Matter
We propose and examine a new set of benchmark supersymmetric scenarios, some
of which have non-universal Higgs scalar masses (NUHM) and others have
gravitino dark matter (GDM). The scalar masses in these models are either
considerably larger or smaller than the narrow range allowed for the same
gaugino mass m_{1/2} in the constrained MSSM (CMSSM) with universal scalar
masses m_0 and neutralino dark matter. The NUHM and GDM models with larger m_0
may have large branching ratios for Higgs and/or production in the cascade
decays of heavier sparticles, whose detection we discuss. The phenomenology of
the GDM models depends on the nature of the next-to-lightest supersymmetric
particle (NLSP), which has a lifetime exceeding 10^4 seconds in the proposed
benchmark scenarios. In one GDM scenario the NLSP is the lightest neutralino
\chi, and the supersymmetric collider signatures are similar to those in
previous CMSSM benchmarks, but with a distinctive spectrum. In the other GDM
scenarios based on minimal supergravity (mSUGRA), the NLSP is the lighter stau
slepton {\tilde \tau}_1, with a lifetime between ~ 10^4 and 3 X 10^6 seconds.
Every supersymmetric cascade would end in a {\tilde \tau}_1, which would have a
distinctive time-of-flight signature. Slow-moving {\tilde \tau}_1's might be
trapped in a collider detector or outside it, and the preferred detection
strategy would depend on the {\tilde \tau}_1 lifetime. We discuss the extent to
which these mSUGRA GDM scenarios could be distinguished from gauge-mediated
models.Comment: 52 pages LaTeX, 13 figure
Colliders and Cosmology
Dark matter in variations of constrained minimal supersymmetric standard
models will be discussed. Particular attention will be given to the comparison
between accelerator and direct detection constraints.Comment: Submitted for the SUSY07 proceedings, 15 pages, LaTex, 26 eps figure
Nottingham Prognostic Index Plus (NPI+): a modern clinical decision making tool in breast cancer
Current management of breast cancer (BC) relies on risk stratification based on well-defined clinicopathologic factors. Global gene expression profiling studies have demonstrated that BC comprises distinct molecular classes with clinical relevance. In this study, we hypothesized that molecular features of BC are a key driver of tumour behaviour and when coupled with a novel and bespoke application of established clinicopathologic prognostic variables, can predict both clinical outcome and relevant therapeutic options more accurately than existing methods. In the current study, a comprehensive panel of biomarkers with relevance to BC was applied to a large and well-characterised series of BC, using immunohistochemistry and different multivariate clustering techniques, to identify the key molecular classes. Subsequently, each class was further stratified using a set of well-defined prognostic clinicopathologic variables. These variables were combined in formulae to prognostically stratify different molecular classes, collectively known as the Nottingham Prognostic Index Plus (NPI+). NPI+ was then used to predict outcome in the different molecular classes with.Seven core molecular classes were identified using a selective panel of 10 biomarkers. Incorporation of clinicopathologic variables in a second stage analysis resulted in identification of distinct prognostic groups within each molecular class (NPI+). Outcome analysis showed that using the bespoke NPI formulae for each biological breast cancer class provides improved patient outcome stratification superior to the traditional NPI. This study provides proof-of-principle evidence for the use of NPI+ in supporting improved individualised clinical decision making
Relating the CMSSM and SUGRA models with GUT scale and Super-GUT scale Supersymmetry Breaking
While the constrained minimal supersymmetric standard model (CMSSM) with
universal gaugino masses, m_{1/2}, scalar masses, m_0, and A-terms, A_0,
defined at some high energy scale (usually taken to be the GUT scale) is
motivated by general features of supergravity models, it does not carry all of
the constraints imposed by minimal supergravity (mSUGRA). In particular, the
CMSSM does not impose a relation between the trilinear and bilinear soft
supersymmetry breaking terms, B_0 = A_0 - m_0, nor does it impose the relation
between the soft scalar masses and the gravitino mass, m_0 = m_{3/2}. As a
consequence, tan(\beta) is computed given values of the other CMSSM input
parameters. By considering a Giudice-Masiero (GM) extension to mSUGRA, one can
introduce new parameters to the K\"ahler potential which are associated with
the Higgs sector and recover many of the standard CMSSM predictions. However,
depending on the value of A_0, one may have a gravitino or a neutralino dark
matter candidate. We also consider the consequences of imposing the
universality conditions above the GUT scale. This GM extension provides a
natural UV completion for the CMSSM.Comment: 16 pages, 11 figures; added erratum correcting several equations and
results in Sec.2, Sec.3 and 4 remain unaffected and conclusions unchange
Theoretical predictions for the direct detection of neutralino dark matter in the NMSSM
We analyse the direct detection of neutralino dark matter in the framework of
the Next-to-Minimal Supersymmetric Standard Model. After performing a detailed
analysis of the parameter space, taking into account all the available
constraints from LEPII, we compute the neutralino-nucleon cross section, and
compare the results with the sensitivity of detectors. We find that sizable
values for the detection cross section, within the reach of dark matter
detectors, are attainable in this framework. For example, neutralino-proton
cross sections compatible with the sensitivity of present experiments can be
obtained due to the exchange of very light Higgses with m_{h_1^0}\lsim 70
GeV. Such Higgses have a significant singlet composition, thus escaping
detection and being in agreement with accelerator data. The lightest neutralino
in these cases exhibits a large singlino-Higgsino composition, and a mass in
the range 50\lsim m_{\tilde\chi_1^0}\lsim 100 GeV.Comment: Final version to appear in JHEP. References added. LaTeX, 53 pages,
23 figure
On B_s -> mu+ mu- and Cold Dark Matter Scattering in the MSSM with Non-Universal Higgs Masses
We show that present experimental constraints on B_s -> mu+ mu- decay and the
CDMS upper limit on the cold dark matter elastic scattering cross section
already have significant impact on the parameter space of the minimal
supersymmetric extension of the Standard Model (MSSM) with non-universal
supersymmetry-breaking scalar masses for the Higgs multiplets (NUHM). The
relaxation of scalar universality in the MSSM allows the possibility of a
relatively light mass M_A for the pseudoscalar Higgs boson. The present upper
limit on B_s -> mu+ mu- already excludes much of the scope for this possibility
in the NUHM, in contrast to the constrained MSSM with universal scalar masses
(CMSSM), where B_s -> mu+ mu- decay does not exclude any ranges of parameters
not already excluded by b -> s \gamma decay. Cold dark matter scattering is
also enhanced for small M_A, but the impact of present upper limit on B_s ->
mu+ mu- on the NUHM parameter space is in many cases greater than that of the
CDMS scattering limit, particularly at large tanb.Comment: 17 pages, 14 eps figure
Reheating Temperature and Gauge Mediation Models of Supersymmetry Breaking
For supersymmetric theories with gravitino dark matter, the maximal reheating
temperature consistent with big bang nucleosynthesis bounds arises when the
physical gaugino masses are degenerate. We consider the cases of a stau or
sneutrino next-to-lightest superpartner, which have relatively less constraint
from big bang nucleosynthesis. The resulting parameter space is consistent with
leptogenesis requirements, and can be reached in generalized gauge mediation
models. Such models illustrate a class of theories that overcome the well-known
tension between big bang nucleosynthesis and leptogenesis.Comment: 30 pages, 4 figures; v2: refs adde
WMAP-Compliant Benchmark Surfaces for MSSM Higgs Bosons
We explore `benchmark surfaces' suitable for studying the phenomenology of
Higgs bosons in the minimal supersymmetric extension of the Standard Model
(MSSM), which are chosen so that the supersymmetric relic density is generally
compatible with the range of cold dark matter density preferred by WMAP and
other observations. These benchmark surfaces are specified assuming that
gaugino masses m_{1/2}, soft trilinear supersymmetry-breaking parameters A_0
and the soft supersymmetry-breaking contributions m_0 to the squark and slepton
masses are universal, but not those associated with the Higgs multiplets (the
NUHM framework). The benchmark surfaces may be presented as M_A-tan_beta planes
with fixed or systematically varying values of the other NUHM parameters, such
as m_0, m_{1/2}, A_0 and the Higgs mixing parameter mu. We discuss the
prospects for probing experimentally these benchmark surfaces at the Tevatron
collider, the LHC, the ILC, in B physics and in direct dark-matter detection
experiments. An Appendix documents developments in the FeynHiggs code that
enable the user to explore for her/himself the WMAP-compliant benchmark
surfaces.Comment: Minor corrections, references added. 43 pages, 10 figures. Version to
appear in JHE
Neutralino-Nucleon Cross Section and Charge and Colour Breaking Constraints
We compute the neutralino-nucleon cross section in several supersymmetric
scenarios, taking into account all kind of constraints. In particular, the
constraints that the absence of dangerous charge and colour breaking minima
imposes on the parameter space are studied in detail. In addition, the most
recent experimental constraints, such as the lower bound on the Higgs mass, the
branching ratio, and the muon are considered. The
astrophysical bounds on the dark matter density are also imposed on the
theoretical computation of the relic neutralino density, assuming thermal
production. This computation is relevant for the theoretical analysis of the
direct detection of dark matter in current experiments. We consider first the
supergravity scenario with universal soft terms and GUT scale. In this scenario
the charge and colour breaking constraints turn out to be quite important, and
\tan\beta\lsim 20 is forbidden. Larger values of can also be
forbidden, depending on the value of the trilinear parameter . Finally, we
study supergravity scenarios with an intermediate scale, and also with
non-universal scalar and gaugino masses where the cross section can be very
large.Comment: Final version to appear in JHE
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