Orientation of drill core by use of borehole geophysical imaging

Borehole core must be orientated relative to a geographic coordinate system if meaningful geological, structural and geotechnical information is to be derived from it. This can be achieved by matching core features with features revealed by geophysical images of the borehole wall. The orientation of a reference line marked on the drill core can thereby be calculated, along with the dip and azimuth of any significant features found in the core. A technique developed by the British Geological Survey (BGS) on the basis of borehole imaging is described here and evaluated in the light of results obtained in the orientation of core extracted on behalf of United Kingdom Nirex, Ltd (Nirex)

Study of the dependence of 198Au half-life on source geometry

We report the results of an experiment to determine whether the half-life of \Au{198} depends on the shape of the source. This study was motivated by recent suggestions that nuclear decay rates may be affected by solar activity, perhaps arising from solar neutrinos. If this were the case then the $\beta$-decay rates, or half-lives, of a thin foil sample and a spherical sample of gold of the same mass and activity could be different. We find for \Au{198}, $(T_{1/2})_{\rm foil}/(T_{1/2})_{\rm sphere} = 0.999 \pm 0.002$, where $T_{1/2}$ is the mean half-life. The maximum neutrino flux at the sample in our experiments was several times greater than the flux of solar neutrinos at the surface of the Earth. We show that this increase in flux leads to a significant improvement in the limits that can be inferred on a possible solar contribution to nuclear decays.Comment: 5 pages, 1 figur

Application of the group-theoretical method to physical problems

The concept of the theory of continuous groups of transformations has attracted the attention of applied mathematicians and engineers to solve many physical problems in the engineering sciences. Three applications are presented in this paper. The first one is the problem of time-dependent vertical temperature distribution in a stagnant lake. Two cases have been considered for the forms of the water parameters, namely water density and thermal conductivity. The second application is the unsteady free-convective boundary-layer flow on a non-isothermal vertical flat plate. The third application is the study of the dispersion of gaseous pollutants in the presence of a temperature inversion. The results are found in closed form and the effect of parameters are discussed

Motivation as a predictor of outcomes in school-based humanistic counselling

Recent years have seen a growth in the provision of counselling within UK secondary schools, and research indicates that it is associated with significant reductions in psychological distress. However, little is known about the moderators and mediators of positive therapeutic benefit. In the field of adult mental health, motivation has been found to be one of the strongest predictors of therapeutic outcomes, and it was hypothesised that this may also be a predictor of outcomes for young people in school-based counselling services. To assess the relationship between young people’s motivation for counselling and its effectiveness within a secondary school setting. Eighty-one young people (12 - 17 years old) who attended school-based humanistic counselling services in Scotland. Clients completed a measure of motivation for counselling at the commencement of their therapeutic work and a measure of psychological wellbeing at the commencement and termination of counselling. Motivation for counselling was not found to be significantly related to outcomes. The results indicate that the association between motivation and outcomes may be weaker in young people as compared with adults. However, a number of design factors may also account for the non-significant findings: insufficient participants, marginal reliability of the motivation measure and social desirability effects

Energy Scaling of Minimum-Bias Tunes

We propose that the flexibility offered by modern event-generator tuning tools allows for more than just obtaining "best fits" to a collection of data. In particular, we argue that the universality of the underlying physics model can be tested by performing several, mutually independent, optimizations of the generator parameters in different physical regions. For regions in which these optimizations return similar and self-consistent parameter values, the model can be considered universal. Deviations from this behavior can be associated with a breakdown of the modeling, with the nature of the deviations giving clues as to the nature of the breakdown. We apply this procedure to study the energy scaling of a class of minimum-bias models based on multiple parton interactions (MPI) and pT-ordered showers, implemented in the Pythia 6.4 generator. We find that a parameter controlling the strength of color reconnections in the final state is the most important source of non-universality in this model.Comment: 17 pages, 3 figures, 4 table

Searches for solar-influenced radioactive decay anomalies using Spacecraft RTGs

Experiments showing a seasonal variation of the nuclear decay rates of a number of different nuclei, and decay anomalies apparently related to solar flares and solar rotation, have suggested that the Sun may somehow be influencing nuclear decay processes. Recently, Cooper searched for such an effect in $^{238}$Pu nuclei contained in the radioisotope thermoelectric generators (RTGs) on board the Cassini spacecraft. In this paper we modify and extend Cooper's analysis to obtain constraints on anomalous decays of $^{238}$Pu over a wider range of models, but these limits cannot be applied to other nuclei if the anomaly is composition-dependent. We also show that it may require very high sensitivity for terrestrial experiments to discriminate among some models if such a decay anomaly exists, motivating the consideration of future spacecraft experiments which would require less precision.Comment: 8 pages, 4 figures (to appear in Astroparticle Physics

Evaluation of the exposure, dose-response and fate in the lung and pleura of chrysotile-containing brake dust compared to TiO2, chrysotile, crocidolite or amosite asbestos in a 90-day quantitative inhalation toxicology study – Interim results Part 1: Experimental design, aerosol exposure, lung burdens and BAL

Abstract: This 90-day repeated-dose inhalation toxicology study of brake-dust (BD) (brakes manufactured with chrysotile) in rats provides a comprehensive understanding of the biokinetics and potential toxicology in the lung and pleura. Exposure was 6 h/d, 5d/wk., 13wks followed by lifetime observation (~20 % survival). Control groups included a particle control (TiO2), chrysotile, commercial crocidolite and amosite asbestos. Aerosol fiber distributions of the chrysotile, crocidolite and amosite were similar (fibers L > 20 μm/cm3 : chrysotile-Low/High 29/72; crocidolite 24; amosite 47 fibers/cm3 ; WHO-fibers/cm3 : chrysotile-Low/High 119/ 233; crocidolite 181; amosite 281 fibers/cm3 ). The number of particles/cm3 in the BD was similar to that in the chrysotile, crocidolite & amosite exposures (BD 470–715; chrysotile 495–614; crocidolite 415; amosite 417 particles/cm3 ). In the BD groups, few fibers L > 20 μm were observed in the lungs at the end of exposure and no fibers L > 20 μm at 90d post exposure. In the chrysotile groups, means of 204,000 and 290,000 fibers(L > 20 μm)/ lung were measured at 89d. By 180d, means of 1 and 3.9 fibers were counted on the filter corresponding to 14,000 and 55,000 fibers(L > 20 μm)/lung. In the crocidolite and amosite groups mean lung concentrations were 9,055,000 and 11,645,000 fibers (L > 20 μm)/lung at 89d. At 180d the means remained similar with 8,026,000 and 11,591,000 fibers (L > 20 μm)/lung representing 10–13% of the total lung fibers. BAL determined the total number of macrophages, lymphocytes, neutrophils, eosinophils, epithelial-cells and IL-1 beta, TNF-alpha and TGF-beta. At the moderate aerosol concentrations used in this study, neutrophil counts increased ~5 fold in the amphibole asbestos exposure groups. All other groups and parameters showed no important differences at these exposure concentrations. The exposure and lung burden results provide a sound basis for assessing the potential toxicity of the brake dust in comparison to the TiO2 particle control and the chrysotile, crocidolite and amosite asbestos control groups. The BAL results provide an initial indication of the differential response. Part 2 presents the presentation and discussion of the histopathological and confocal microscopy findings in this study through 90 days post exposure

Defective protein prenylation is a diagnostic biomarker of mevalonate kinase deficiency

Contains fulltext : 177329.pdf (Publisher’s version ) (Open Access

Translation to practice: a randomised controlled study of an evidenced based booklet targeted at breast care nurses in the United Kingdom

BACKGROUND: In the United Kingdom (UK), it was documented that a problem of knowledge transfer existed within the speciality of breast-cancer care, thus depriving patients of receiving optimal care. Despite increasingly robust research evidence indicating recommendation of whole body exercise for people affected by breast cancer, commensurate changes to practice were not noted amongst breast-care nurses (BCNs). AIM: To evaluate the effect of a targeted booklet, Exercise and Breast Cancer: A Booklet for Breast-Care Nurses, on changes in knowledge, reported practice, and attitudes of BCNs in the UK. METHOD: A prospective, experimental approach was used for designing a pre- and post-test randomised controlled study. Comparisons of knowledge, reported practice, and attitudes based on responses to a questionnaire were made at two time-points in two groups of BCNs (control and experimental). The unit of randomisation and analysis was hospital clusters of BCNs. The sample comprised 92 nurses from 62 hospitals. Analysis consisted of descriptive statistics and clustered regression techniques: clustered logistic regression for knowledge items, clustered linear regression for knowledge scores, ologit for attitude and reported practice items, and clustered multiple regression for paired and multiple variable analysis. RESULTS: A statistically significant increase in knowledge and changes in reported practice and attitudes were found. Robust variables affecting knowledge acquisition were: promotion of health, promotion of exercise, and understanding how exercise can reduce cancer-related fatigue. DISCUSSION: The study has shown that evidence-based printed material, such as an information booklet, can be used as an effective research dissemination method when developed for needs, values, and context of a target audience. CONCLUSIONS: This practical approach to research dissemination could be replicated and applied to other groups of nurses.</p

Effect of Spatial Locality on an Evolutionary Algorithm for Multimodal Optimization

Abstract. To explore the effect of spatial locality, crowding differential evolu-tion is incorporated with spatial locality for multimodal optimization. Instead of random trial vector generations, it takes advantages of spatial locality to generate fitter trial vectors. Experiments were conducted to compare the proposed algo-rithm (CrowdingDE-L) with the state-of-the-art algorithms. Further experiments were also conducted on a real world problem. The experimental results indicate that CrowdingDE-L has a competitive edge over the other algorithms tested.