8 research outputs found

    NN<sup>k</sup> networks for Content-Based Image Retrieval

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    This paper describes a novel interaction technique to support content-based image search in large image collections. The idea is to represent each image as a vertex in a directed graph. Given a set of image features, an arc is established between two images if there exists at least one combination of features for which one image is retrieved as the nearest neighbour of the other. Each arc is weighted by the proportion of feature combinations for which the nearest neighbour relationship holds. By thus integrating the retrieval results over all possible feature combinations, the resulting network helps expose the semantic richness of images and thus provides an elegant solution to the problem of feature weighting in content-based image retrieval.We give details of the method used for network generation and describe the ways a user can interact with the structure. We also provide an analysis of the network’s topology and provide quantitative evidence for the usefulness of the technique

    The <i>Ectocarpus</i> genome and the independent evolution of multicellularity in brown algae

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    Brown algae (Phaeophyceae) are complex photosynthetic organisms with a very different evolutionary history to green plants, to which they are only distantly related1. These seaweeds are the dominant species in rocky coastal ecosystems and they exhibit many interesting adaptations to these, often harsh, environments. Brown algae are also one of only a small number of eukaryotic lineages that have evolved complex multicellularity (Fig. 1).We report the 214 million base pair (Mbp) genome sequence of the filamentous seaweed Ectocarpus siliculosus (Dillwyn) Lyngbye, a model organism for brown algae, closely related to the kelps (Fig. 1). Genome features such as the presence of an extended set of light-harvesting and pigment biosynthesis genes and new metabolic processes such as halide metabolism help explain the ability of this organism to cope with the highly variable tidal environment. The evolution of multicellularity in this lineage is correlated with the presence of a rich array of signal transduction genes. Of particular interest is the presence of a family of receptor kinases, as the independent evolution of related molecules has been linked with the emergence of multicellularity in both the animal and green plant lineages. The Ectocarpus genome sequence represents an important step towards developing this organism as a model species, providing the possibility to combine genomic and genetic2 approaches to explore these and other aspects of brown algal biology further

    Three Interfaces for Content-Based Access to Image Collections

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    Abstract. This paper describes interfaces for a suite of three recently developed techniques to facilitate content-based access to large image and video repositories. Two of these techniques involve content-based retrieval while the third technique is centered around a new browsing structure and forms a useful complement to the traditional query-byexample paradigm. Each technique is associated with its own user interface and allows for a different set of user interactions. The user can move between interfaces whilst executing a particular search and thus may combine the particular strengths of the different techniques. We illustrate each of the techniques using topics from the TRECVID 2003 contest.

    Explosive Electric Power for Mining Applications

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    Pulsed-power driven explosion of water or other dense media is a challenging area of research, applications, and commercialization. This work gives a simplified description of involved mechanisms and a selection of test results. Applications for mining, drilling, excavation, off-shore and on-shore are in development.</p

    Assessing User Behaviour in News Video Retrieval

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    Abstract. In this paper we present the results of a study in which we assess search behaviour of people querying a news archive using an interactive video retrieval system. 242 Search sessions by 39 participants on 24 topics were analysed. Before, during and after the study, participants filled in questionnaires about their expectations of a search. The questionnaire data, logged user actions on the system, queries formulated by users, and a quality measure of each search were studied. The results of the study show that topics concerning ‘specific ’ people or objects were better retrieved than topics concerning ‘general ’ objects and scenes. Users were able to estimate the overall quality of a search but did not know when the optimal result was reached within the search process. Analysis of the results at various stages in the retrieval process suggests that retrieval based on transcriptions of the speech in video data adds more to the average precision of the result than content-based image retrieval based on low-level visual features. The latter is particularly useful in providing the user with an overview of the dataset and thus an indication of the success of a search. Based on the results we discuss implications for the design of user interfaces of video retrieval systems.

    Evolution of translational control and the emergence of genes and open reading frames in human and non-human primate hearts

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    Evolutionary innovations can be driven by changes in the rates of RNA translation and the emergence of new genes and small open reading frames (sORFs). In this study, we characterized the transcriptional and translational landscape of the hearts of four primate and two rodent species through integrative ribosome and transcriptomic profiling, including adult left ventricle tissues and induced pluripotent stem cell-derived cardiomyocyte cell cultures. We show here that the translational efficiencies of subunits of the mitochondrial oxidative phosphorylation chain complexes IV and V evolved rapidly across mammalian evolution. Moreover, we discovered hundreds of species-specific and lineage-specific genomic innovations that emerged during primate evolution in the heart, including 551 genes, 504 sORFs and 76 evolutionarily conserved genes displaying human-specific cardiac-enriched expression. Overall, our work describes the evolutionary processes and mechanisms that have shaped cardiac transcription and translation in recent primate evolution and sheds light on how these can contribute to cardiac development and disease

    Cocaine Cardiotoxicity

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