A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFECT OF TANDULIYAKA IN GARBHINI PANDU W.S.R. TO ANAEMIA DURING PREGNANCY

Under-nutrition and micronutrient deficiencies are widespread and affect mainly women and children. To address these problems, increased consumption of leafy vegetables is promoted as sources of both micronutrients and bio-active compounds. Widely promoted leafy vegetables include Amaranthus sp., Species of this genus are used as pseudo-cereals in Europe and America, and are mostly planted as vegetables in Africa. Amaranthus has been rediscovered as a promising food crop mainly due to its resistance to heat, drought, diseases and pests, and the high nutritional value of both seeds and leaves. Leaves are rich in proteins and micronutrients such as iron, calcium, zinc, vitamin C and vitamin A. Pregnancy induces some physiological changes that often confuse the diagnosis of several disorders and the assessment of the suitable treatments. This is especially true in case of anaemia. The World Health Organization estimates that 58% of pregnant women in developing countries are anaemic. The two most common causes of anaemia during pregnancy are iron deficiency and acute blood loss. Iron deficiency anaemia is the most common nutritional disorder in the world that affects particularly women of reproductive age. In the present study Amaranthus capsules showed significant improvement in terms of subjective parameters like Panduta, Hrid-drava, Shrama, Swasa, Aruchi, as well as objective parameters like Hb%, MCV, PCV, RBC etc. This study has revealed that Amaranthus capsules provided statistically significant improvement in the cardinal features of Garbhinipandu as well as it has showed good effect on jatharagni and nourishment of pregnant women and foetus without any side-effects, due to its properties like deepana, pachana, and high nutritional value

A COMPREHENSIVE REVIEW OF A HEALING HERB: TRIDAX PROCUMBENS LINN.

Nature has been a source of medicinal agents for thousands of years and an impressive number of medicinal drugs have been isolated from natural resources. It is now a known fact that nature has given cure of every disease in one way or another but the only need is to explore them wisely. So the researchers today are emphasizing on evolution & characterization of various plants & plant constituents against different diseases. The essential uses of many plants have been worked out & published but many useful and valuable plants are still unexplored upto date. One such plant/drug is Tridax procumbens Linn commonly called as coat button in English and Ghamra in Hindi. Though it has been used in folklore practices for hundreds of years but still it is considered a useless weed in many parts of the world. It is a multifaceted weed available throughout the continent which can act as a substitute for many herbs. The present endeavour is an attempt to analyse the updated information of Tridax identification, phytochemical, pharmacogonostic study and its pharmacological activities like hepatoprotective activity, antimicrobial activity, immunomodulating property, defluoridation activity, hypotensive action, anti viral action, anti oxidant action, antiurolithiatic action and anti inflammatory action to serve the ailing mankind by its magical action

MUSALI - A DIVINE HERB WITH ITS MEDICINAL USES

Musali is one of the reputed drug mentioned in the ancient books of Ayurveda and Siddha. It is good for all round development of health Musali is called as Divine Medicine for its medicinal qualities. Musali is also called Talamuli, Suvaha, Talamulika, Deerghakandika, Talapatri in Ayurveda. Acharya Charaka describe Musali in the treatment of respiratory disorders. Sushruta mentioned it in the treatment of Urolithiasis and in the treatment of Chronic obstructive pulmonary disease. In Rajnighantu it has been described as sweet, cooling, mucilaginous, increase Kapha and reduces Pitta daha (burning sensation), act as stimulant, gives strength. It is one of the important Rasayana drugs of Ayurvedic Materia Medica for vigour and vitality. It is an important ingredient of many Ayurvedic preparation and is considered to have aphrodisiac, immunostimulant, hepatoprotective, antioxidant, anticancer and antidiabetic activities. Hence the present study include its general introduction its type, Ayuredic literature, pharmacological activities and variable uses of Musali in several disease.&nbsp

AJAMODA (APIUM LEPTOPHYLUM)- A NATURAL PAINKILLER

Ajamoda is an important drug of Ayurveda, Siddha and Unani systems of medicine, which consists of umbelliferous fruits.  The drug to be used in the formulations are fruits of Apium leptophyllum. Apium is a genus of about 20 species of flowering plants in the family Apiaceae. Some species are edible, notably Apium graveolance, Apium leptophylum, which includes the commercially important vegetables celery, celeriac and chinese celery. It is grown extensively in the South Asia, Southeast Asia, and Indonesia. Its aromatic dried fruits, like its close relative ajwain, are often used in Bengali cuisine but are rarely used in the rest of India. The fresh leaves are used as an herb in Thailand and it is used medicinally in Myanmar. The small dried fruits, commonly referred to as seeds, are similar in appearance to those of ajwain, celery, and caraway. Because of their similarity in both appearance and flavor, it is often confused or substituted with celery seed. Ajamoda consists of dried, aromatic fruits of Apium leptophyllum (Pers.) F. V. M. ex Benth. (Fam. Umbelliferae); an annual herb cultivated in Andhra Pradesh, Gujarat, Madhya Pradesh and Karnataka; collected by thrashing plants on a mat and dried in shade or in drying sheds. The oil of seeds of Ajamoda is also used in compounding Ayurvedic formulations. While, fatty oil of seeds is antispasmodic and nerve stimulant, seeds of celery are rich in vitamin-B

CASE REPORT ON MOCHARASA (HAEMOSTYPTIC DRUG)- ACTION AND USES

Medicinal plants are resources of newer drug evolution and form the basis of all alternative medicine system. Mocharasa-reddish brown colored secondary metabolite in the form of exudate from Silk - Cotton Tree (Salmali malabarica) and is in demand in pharmaceutical industries for preparation of formulations used for bleeding disorders. Mochrasa is one of source for the life saving drug and known by synonyms like “Niryasa, Pichha, Pichhalsaar, Salmaliveshtaka, Mochsrava, Mochsaar denoting its sticky characteristic. Their therapeutic uses are well described in Ayurvedic, Unani and Siddha literature in various bleeding disorders like menorragia, haemptysis, bloody dysentery, diarrhoea mainly. It has good potential of cooling, demulscent, haemostyptic and astringent nature. Due to its binding nature used to heal wounds, ulcers, inflammation and in skin disorders. It is well known for aphrodiasic action in traditional practices as well. It is mild in nature and can be used in pregnant women and children. In Shodhana process of Panchkarma, it is main content of “ Pichha basti †which is given per rectal route which proves its mild astringent and styptic action. Main chemical constituents are L-arbanose, gallic acid, tannic acid with other alkaloids. Various formulations containing Mochrasa are Sunisnaak Changeri Ghrita, Bilwaadi churna, Kutajastak avhleha, Sammangaadi Churna, Changeri Ghrita etc. Various newer trials for antioxidant, analgesic, hepatoprotective action etc. are going on the basis of properties to revalidate the ancient knowledge. Here is an attempt to through light on collection process, purification and availability of raw drug as well extracts in market by collecting data from various sources on every aspect of Mocharasa and their therapeutic and folklore uses

Successful use of steroids and ureteric stents in 24 patients with idiopathic retroperitoneal fibrosis : a retrospective study

Original article can be found at : http://content.karger.com/ Copyright Karger [Full text of this article is not available in the UHRA]Background/Aims: Retroperitoneal fibrosis (RPF) is a chronic inflammatory disorder causing obstructive nephropathy and renal failure. We reviewed our management of this condition. Method: All patients with RPF treated at a single center over a 15-year period were identified. A full review of notes and computer records was undertaken. Results: Data was available on 27 patients, 3 of which were excluded from later analysis. Diagnosis was based on clinical history and cross-sectional imaging. Retroperitoneal biopsy was undertaken in 3 patients. 96% had significant renal impairment at presentation with a mean serum creatinine of 688 μmol/l. 46% required emergency hemodialysis. All patients were treated with a combination of ureteric stents and/or steroids with an excellent clinical response. The mean best creatinine reached by the cohort was 136 μmol/l, and renal function remained stable in the long term. No patients required chronic dialysis. Ureteric stents were removed within 12 months and low-dose steroids were continued for a mean of 34 months. Recurrent disease was observed in 25% of patients, who all responded well to further steroid therapy. Mean duration of follow-up was 76 months. Conclusions: RPF is very effectively treated by a combination of ureteric stents and steroids, with excellent long-term results using this approach. Continued follow-up is advised because of the possibility of recurrent disease.Peer reviewe

A PRECIOUS HERB - GMELINA ARBOREA LINN. W.S.R TO ITS MEDICINAL USES AND PHARMACOLOGICAL ACTIVITY

Traditional medicines play an important role in health services around the globe. About three quarter of the world population relies on plants and plant product for health care. Gmelina arborea Linn. an important medicinal plant is one of the most widely cultivated species of the family Verbenaceae. It is commonly known as Gambhari,  the term actually used by tribal people of Bihar. It is one of the herb mentioned in all ancient literature of Ayurveda in diseases like ulcer, diarrhoea, thirst, anaemia, leprosy, vaginal discharge, piles, fever and varieties of ailments. It is highly valued from the immemorial because of its vast medicinal properties. Gambhari is a fast growing deciduous tree occurring naturally throughout greater part of India at altitudes up to 1,500 meters. It is an essential component of Dashamula dravya (group of ten roots) and has been used for its valuable medicinal properties like Medhya (Intellect power), Keshya (Hair tonic) and Rasayana (Rejuvenator). Acharya Charaka mentioned Gambhari in Sothahara, Dahaprasamana, Virecanopaga mahakasaya and also explain its fruit as best among Rakta-Sangrahaka and Raktapittahara. The roots,  fruits and the leaves of Gambhari have great medicinal value therefore traditionally it was widely used as anthelmintic, antimicrobial, anti-diabetic, anti-aging, analgesic, diuretic, hepato-protective and antiepileptic agent. The present article provides all necessary information regarding its classical literature, general introduction, medicinal uses of its roots, leaves, flowers, fruit, bark, and pharmacological studies conducted till date

A CRITICAL REVIEW ON GUGGULU [COMMIPHORA WIGHTII (ARN.) BHAND.] & ITS MIRACULOUS MEDICINAL USES

Guggulu has been a key component in ancient Indian Ayurvedic system of medicine. It has been used extensively by Ayurvedic physicians for centuries to treat a wide variety of disorders, besides its use in pharmaceutical and perfumery industries. Guggulu is a gum or resin extracted from the plant Commiphora wightii (Arn.) Bhand. (Syn. Commiphora mukul Hook. ex. Stocks) or Guggulu tree. Guggulu is a shrub or small tree belonging to Burseraceae family. Guggulu contains volatile oil, gum resin, gugulipids, guggulsterones, guggulsterols, mukolol and other steroids. Guggulu is very much used in Ayuvedic system of medicine as astringent, anti-septic, expectorant, aphrodisiac, carminative, anti-spasmodic, emmenagogue. In Ayurveda, Guggulu is the best among herbs that are used for Medoroga and Vata disorders. It is widely used for obesity and it is also known as fat burning agent all over the world. It helps to lower cholesterol and triglycerides level. Guggulu is very effective in rheumatoid arthritis, gout and sciatica. It is also one of the most important Rasayana of Ayurveda. In addition it treats sluggish liver, stimulates libido, nervous diseases, bronchial congestion, cardiac and circulatory problems, weak digestion, wounds, abscess, foetid ear, fractures, gynaecological problems and various skin diseases. Guggulu is a very important and trustworthy herb in Ayurvedic medicine. Basically it is used almost in every kind of illness due to its amazing treating power. This review is an attempt to describe the pharmacological activities of Guggulu and variable uses of Guggulu in several diseases

A INTACT REVIEW ON NELUMBO NUCIFERA W.S.R TO ITS THERAPEUTIC POTENTIAL

Last few decades have again shown a notable interest in herbal products for food or in medicinal aspect, the reason behind this is the increasing awareness about the limitations of the synthetic agents. Kamal is a well known plant in ancient medical sciences. It is extensively described in almost all Samhitas and Nighantus of Ayurveda, which reflects its great medicinal value. It has been used extensively by Ayurvedic Physicians for centuries to treat a wide variety of disorders. It is edible used for food and medicine both. Kamal is Nelumbo nucifera Grertn (syn. Nelumbium speciosum Willd.; Nymphaea nelumbo Linn.) of Nelumbonaceae family. It is a perennial aquatic herb bearing the famous red lotus flowers. It has miraculous cooling effect and anti-haemorrhagic property. Its flowers contain robinin an glucoside. Leaves contains nuciferine an alkaloid, asmilobine & irinidine. Root contain isoliensinine neferine, seed contains armeparine. The different part contains different chemical constituents which enhance its medicinal value in different diseases. This article review the Ayurvedic literature, traditional uses, phytochemistry & therapeutic reports on different parts of N. nucifera. The review also describes various compound isolated from different parts of this plant & the therapeutic benefits derived from those phytoconstituents

A Multicast Protocol for Content-Based Publish-Subscribe Systems

The publish/subscribe (or pub/sub) paradigm is a simple and easy to use model for interconnecting applications in a distributed environment. Many existing pub/sub systems are based on pre-defined subjects, and hence are able to exploit multicast technologies to provide scalability and availability. An emerging alternative to subject-based systems, known as content-based systems, allow information consumers to request events based on the content of published messages. This model is considerably more flexible than subject-based pub/sub, however it was previously not known how to efficiently multicast published messages to interested content-based subscribers within a network of broker (or router) machines. In this paper, we develop and evaluate a novel and efficient technique for multicasting within a network of brokers in a content-based subscription system, thereby showing that content-based pub/sub can be deployed in large or geographically distributed settings