Weak corrections to Higgs hadroproduction in association with a top-quark pair

We present the calculation of the next-to-leading contribution of order $\alpha_S^2\alpha^2$ to the production of a Standard Model Higgs boson in association with a top-quark pair at hadron colliders. All effects of weak and QCD origin are included, whereas those of QED origin are ignored. We work in the MadGraph5_aMC@NLO framework, and discuss sample phenomenological applications at a 8, 13, and 100 TeV $pp$ collider, including the effects of the dominant next-to-leading QCD corrections of order $\alpha_S^3\alpha$.Comment: 29 pages, 38 figure

Electroweak and QCD corrections to top-pair hadroproduction in association with heavy bosons

We compute the contribution of order $\alpha_S^2\alpha^2$ to the cross section of a top-antitop pair in association with at least one heavy Standard Model boson -- $Z$, $W^\pm$, and Higgs -- by including all effects of QCD, QED, and weak origin and by working in the automated MadGraph5_aMC@NLO framework. This next-to-leading order contribution is then combined with that of order $\alpha_S^3\alpha$, and with the two dominant lowest-order ones, $\alpha_S^2\alpha$ and $\alpha_S\alpha^2$, to obtain phenomenological results relevant to a 8, 13, and 100~TeV $pp$ collider.Comment: 27 pages, 8 figure

The automation of next-to-leading order electroweak calculations

We present the key features relevant to the automated computation of all the leading- and next-to-leading order contributions to short-distance cross sections in a mixed-coupling expansion, with special emphasis on the first subleading NLO term in the QCD+EW scenario, commonly referred to as NLO EW corrections. We discuss, in particular, the FKS subtraction in the context of a mixed-coupling expansion; the extension of the FKS subtraction to processes that include final-state tagged particles, defined by means of fragmentation functions; and some properties of the complex mass scheme. We combine the present paper with the release of a new version of MadGraph5_aMC@NLO, capable of dealing with mixed-coupling expansions. We use the code to obtain illustrative inclusive and differential results for the 13-TeV LHC.Comment: 121 pages, 16 figure

Deciphering species-specific pollen tube guidance in Solanum

Small, secreted cysteine-rich proteins (CRPs)combine a highly stable cysteine spacing,ensuring conservation of their 3D structure andfunction, and hypervariable inter-cysteine blocks, allowing quick evolution of specific recognition domains. Interestingly, several CRPs were shown to control key pollen-pistil interactions in aspecies-specific way. The most emblematicexample is perhaps the LURE defensin-likefamily, controlling directional guidance of pollentubes (PTs) in Torenia and Arabidopsis.We chose wild potatoes (Solanum sect. Petota) asa case study to investigate the impact of rapidCRP divergence in plant speciation. Gathering ~200 close species with overlapping distribution areas, this taxon indeed exhibits strong reproductive isolation. Lab-on-a-chipmicrofluidic experiments carried out on 4 species show that species-preferential PT attraction is a key factor in this isolation. We suspect polymorphic CRPs to control this attraction. High-throughput sequencing technologies were applied to profile the ovule secretome as well as the reproductive transcriptomes of our 4 speciesof interest. To screen out candidate genes, we developped KAPPA, a sequence search algorithm specifically dedicated to CRPs, and obtained a set of 32 defensin-like groups expressed in ovules. Five promising chemoattractant candidates exhibiting (i) ovule-specific expression, (ii) down-regulation in guidance-defective ovules, and (iii) interspecific divergence were selectedfor further characterization. They are currently being investigated with on-gel assays and specific microfluidic devices tailored for Solanum PTs. This study will lead to a better understanding of CRP-mediated PT chemoattraction as one of the major species-specificity checkpoints that mustbe unlocked by pollen tubes in the pistil.Fil: Joly, V.. Institut de Recherche En Biologie Végétale; CanadáFil: Viallet, C.. Institut de Recherche En Biologie Végétale; CanadáFil: Liu, Y.. Institut de Recherche En Biologie Végétale; CanadáFil: Zaro, A.. Universidad de Barcelona; EspañaFil: Ceriotti, Luis Federico. Universidad Nacional de Cuyo. Facultad de Ciencias Exactas y Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Biología Agrícola de Mendoza. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Instituto de Biología Agrícola de Mendoza; ArgentinaFil: Matton, D. P.. Institut de Recherche En Biologie Végétale; CanadáEastern Regional MeetingMontrealCanadáCanadian Society of Plant BiologistsMcGill Universit

Model-independent extraction of ∣Vtq∣|V_{tq}| matrix elements from top-quark measurements at hadron colliders

Current methods to extract the quark-mixing matrix element $|V_{tb}|$ from single-top production measurements assume that $|V_{tb}|\gg |V_{td}|, |V_{ts}|$: top quarks decay into $b$ quarks with 100% branching fraction, s-channel single-top production is always accompanied by a $b$ quark and initial-state contributions from $d$ and $s$ quarks in the $t$-channel production of single top quarks are neglected. Triggered by a recent measurement of the ratio $R=\frac{|V_{tb}|^{2}}{|V_{td}|^{2}+|V_{ts}|^{2}+|V_{tb}|^{2}}=0.90 \pm 0.04$ performed by the D0 collaboration, we consider a $|V_{tb}|$ extraction method that takes into account non zero d- and s-quark contributions both in production and decay. We propose a strategy that allows to extract consistently and in a model-independent way the quark mixing matrix elements $|V_{td}|$, $|V_{ts}|$, and $|V_{tb}|$ from the measurement of $R$ and from single-top measured event yields. As an illustration, we apply our method to the Tevatron data using a CDF analysis of the measured single-top event yield with two jets in the final state one of which is identified as a $b$-quark jet. We constrain the $|V_{tq}|$ matrix elements within a four-generation scenario by combining the results with those obtained from direct measurements in flavor physics and determine the preferred range for the top-quark decay width within different scenarios.Comment: 36 pages, 17 figure

MFGE8 links absorption of dietary fatty acids with catabolism of enterocyte lipid stores through HNF4γ-dependent transcription of CES enzymes

Enterocytes modulate the extent of postprandial lipemia by storing dietary fats in cytoplasmic lipid droplets (cLDs). We have previously shown that the integrin ligand MFGE8 links absorption of dietary fats with activation of triglyceride (TG) hydrolases that catabolize cLDs for chylomicron production. Here, we identify CES1D as the key hydrolase downstream of the MFGE8-αvβ5 integrin pathway that regulates catabolism of diet-derived cLDs. Mfge8 knockout (KO) enterocytes have reduced CES1D transcript and protein levels and reduced protein levels of the transcription factor HNF4γ. Both Ces1d and Hnf4γ KO mice have decreased enterocyte TG hydrolase activity coupled with retention of TG in cLDs. Mechanistically, MFGE8-dependent fatty acid uptake through CD36 stabilizes HNF4γ protein level; HNF4γ then increases Ces1d transcription. Our work identifies a regulatory network that regulates the severity of postprandial lipemia by linking dietary fat absorption with protein stabilization of a transcription factor that increases expression of hydrolases responsible for catabolizing diet-derived cLDs

Plan de negocio para una fintech que colabora en la colocaci?n y uso de tarjetas de cr?dito de consumo de las empresas financieras y banca m?ltiple

Se realiz? un plan de negocio para formar una Fintech cuyo prop?sito es de colaborar en la colocaci?n y uso de tarjetas de cr?ditos para la banca m?ltiple y financieras, brindando a sus consumidores finales, informaci?n personalizada acerca de los beneficios y promociones de la tarjeta de cr?dito mediante una plataforma digital de recomendaciones. Existen problemas en las entidades bancarias para enviar la informaci?n de los beneficios a los consumidores, tales como: campa?as que no son efectivas al no tener el consentimiento de las personas por la ley de protecci?n de datos y como los consumidores finales no pueden acceder a la informaci?n de una forma f?cil y confiable para utilizar los beneficios y promociones de las tarjetas de cr?ditos. Se realiz? dos estudios de mercado: se valid? las necesidades de los consumidores para medir la intenci?n de uso de beneficios, por ultimo se verific? la necesidad que tienen la financieras en entregar la informaci?n a los consumidores (Banco Falabella y Financiera oh). Por lo tanto, se concluye que la utilizaci?n de la plataforma de recomendaciones para beneficios y promociones es viable por la intenci?n de uso de los consumidores finales y banca m?ltiple y adem?s se demuestra viabilidad econ?mica y tecnol?gica para el plan de negocio de la tesis

Les Houches 2015: Physics at TeV Colliders Standard Model Working Group Report

This Report summarizes the proceedings of the 2015 Les Houches workshop on Physics at TeV Colliders. Session 1 dealt with (I) new developments relevant for high precision Standard Model calculations, (II) the new PDF4LHC parton distributions, (III) issues in the theoretical description of the production of Standard Model Higgs bosons and how to relate experimental measurements, (IV) a host of phenomenological studies essential for comparing LHC data from Run I with theoretical predictions and projections for future measurements in Run II, and (V) new developments in Monte Carlo event generators.Comment: Proceedings of the Standard Model Working Group of the 2015 Les Houches Workshop, Physics at TeV Colliders, Les Houches 1-19 June 2015. 227 page