650 research outputs found
Evaluation of extreme wave probability on the basis of long-term data analysis
A method of calculation of wind wave height probability based on the
significant wave height probability is described (Chalikov and Bulgakov,
2017). The method can also be used for estimation of the height of extreme waves
of any given cumulative probability. The application of the method on the
basis of long-term model data is presented. Examples of averaged annual and
seasonal fields of extreme wave heights obtained using the above method are
given. Areas where extreme waves can appear are shown.</p
TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME
The article reviews modern approaches in complex treatment of patients with diabetic foot syndrome. Authors present their experience with the patients who arrived in planned and emergency order, the criteria of choice of the strategy of surgical treatment of diabetic foot syndrome. Direct and remote results of introduced scheme are studied and. its advantages and. disadvantages are revealed
SCREENING OF POTENTIAL LIGANDS FOR THE MAIN PROTEASE OF THE SARS-COV-2 CORONAVIRUS BY USING MOLECULAR DOCKING
An RNA virus from the Coronaviridae family, a subgroup of Coronavirinae, was first identified in late 2019 as the cause of severe acute respiratory infection in China.1 Despite the fact that clinical guidelines have been developed for the treatment of a new coronavirus infection, there are currently no specific medicine of preventing and treating a new coronavirus infection
Clinical Experience of Luminescent Diagnostics of Precancerous Diseases and Cervical Cancer
The article summarizes the experience of using luminescent diagnostics with the use of ytterbium porphyrin complexes in gynecology and oncology. A pharmaceutical composition based on the Yb complex of 2,4-dimethoxyhematoporphyrin IX was used as the luminescent markers within the infrared range. The determination of luminescence characteristics (luminescence intensity) was carried out using a laserfiber fluorimeter in the range of 900-1100 nm. A new method for diagnosis of cervical disease has been proposed. The method of luminescent diagnostics allows to conduct a survey of a large number of patients in a short time. The method of luminescent diagnostics using the ytterbium complexes of porphyrins is not invasive. The method can be used as a screening. Differences between normal and pathologically altered cervical tissue have been identified and differences between pathological changes in the cervix HSIL (CIN II, CIN III) and cervical cancer are reliable.
Keywords: Cervical cancer, squamous cell carcinoma, diagnosis of cervical cancer, squamous intraepithelial lesions of high grade – HSIL, luminescent diagnostics, luminescing in the near infrared (NIR) spectral region, porphyrins, ytterbium complexes of porphyrins
Increasing the efficiency of investments on survey of abundant land for their return to agricultural us
The "“State program for the effective involvement of abundant agricultural land in the use and the development of the reclamation complex of the Russian Federation” for 2021–2030" assumes the return of 12 million hectares out of 44 million hectares of all abandoned agricultural land (AAL) in the Russian Federation. The costs of 12 million hectares survey can be considered productive, while the costs of surveying the remaining 32 million hectares should be considered unproductive. The application of the new geoinformation database of “Soils of agricultural lands of the Russian Federation” (DB SALRU) developed by the Federal Research Centre “V.V Dokuchaev Soil Sience Institute” allows reduction of unproductive costs. By the example of the Vladimir region, a typical Russian region with AAL, the option of ranking AAL by their quality was demonstrated to determine the order of their return to agricultural use. The soil quality criteria are the bonitet and the normative yield of grain crops, which are part of the DB SALRU. It is proposed to consider the expenditures on the survey of AAL for the soils, which are first to be returned to agricultural use, as productive costs. These soils occupy 25% of the AAL of the region. The best quality soils are characterized by more than 40 points of bonitet and the standard yield of grain crops of more than 20 centners/ha. The cost of surveying the lands of the first order of returning to agricultural use is 10 million 80 thousand rubles. Survey of AAL soils of II–IV orders of involvement in agricultural use, with relatively poor quality compared to the soils of the first order, is proposed to be conducted in the case of expansion of the State program in the future. This would save the unproductive expenses for the survey of AAL for the Vladimir region by 30 million 165.5 thousand rubles. The application of the proposed GIS-approach makes it possible to reduce unproductive expenses for the survey of AAL in the Russian Federation nearly by 5.600 million rubles
MODERN TREATMENT MINIMALLY INVASIVE TECHNOLOGIES RENOVASCULAR HYPERTENSION
The purpose of the research was the study of the effectiveness of balloon angioplasty and stenting of renal arteries to improve the microcirculation of the kidneys in patients with renovascular hypertension. During the period from 2010 to 2012 inclusive in the vascular compartment BSMU clinic were examined and treated 32 patients with renal artery stenosis. Inclusion criteria were: presence of verified violations of regional circulation in the kidney, the presence of symptomatic renovascular hypertension. Measures the average systolic and diastolic blood pressure mast. Patients received antihypertensive treatment to endovascular treatment. Treatment with antihypertensive medication was effective only in 9.8 % of cases. Diagnostic angiography of the renal arteries was performed using angiographic complex INNOVA 3131 IQ. After analyzing the data, the question of stenting or balloon angioplasty. After a detailed survey of 32 patients underwent endovascular intervention for renal artery 6 balloon angioplasty and stenting 26. Following the procedure, the hypotensive effect was observed in all cases. Evaluation of the results showed a significant reduction in the maximum rise in systolic blood pressure by 28 %, diastolic - 21 %. After endovascular intervention, the mean systolic blood pressure decreased by 10%, the average diastolic blood pressure - 15 %. Mean arterial pressure decreased by 8 %. In a review of the effectiveness of endovascular procedures with the original length and the degree of hypertension. Thus, roentgenendovascular treatment improves microcirculation in the renal tissue, which leads to the hypotensive effect of a predominantly marked reduction of maximum systolic blood pressure
Luminescence in anion-deficient hafnia nanotubes
Hafnia-based nanostructures and other high-k dielectrics are promising
wide-gap materials for developing new opto- and nanoelectronics devices. They
possess a unique combination of physical and chemical properties such as
insensitivity to electrical and optical degradation, radiation damage
stability, a high specific surface area, and an increased concentration of the
appropriate active electron-hole centers. The present paper aims to investigate
the structural, optical, and luminescent properties of anodized
non-stoichiometric nanotubes. As-grown amorphous hafnia nanotubes and
nanotubes annealed at 700{\deg}C with a monoclinic crystal lattice served as
samples. It has been shown that the bandgap for direct allowed
transitions amounts to eV for amorphous and eV for
monoclinic nanotubes. For the first time, we have studied the features of the
intrinsic cathodoluminescence and photoluminescence of the obtained nanotubular
structures with an atomic deficiency in the anion sublattice at
temperatures of 10 and 300 K. A broad emission band with a maximum of 2.3-2.4
eV has been revealed. We have also conducted an analysis of the kinetic
dependencies of the observed photoluminescence for synthesized samples
in the millisecond range at room temperature. It showed that there are several
types of optically active capture and emission centers based on vacancy states
in the and positions with different coordination numbers and
a varied number of localized charge carriers (, , and ). The
uncovered regularities can be used to optimize the functional characteristics
of developed-surface luminescent media based on nanotubular and nanoporous
modifications of hafnia.Comment: 15 pages, 6 figures, 3 tables, 50 reference
High frequency magnetic oscillations of the organic metal -(ET)ZnBr(CHCl) in pulsed magnetic field of up to 81 T
De Haas-van Alphen oscillations of the organic metal
-(ET)ZnBr(CHCl) are studied in pulsed magnetic
fields up to 81 T. The long decay time of the pulse allows determining reliable
field-dependent amplitudes of Fourier components with frequencies up to several
kiloteslas. The Fourier spectrum is in agreement with the model of a linear
chain of coupled orbits. In this model, all the observed frequencies are linear
combinations of the frequency linked to the basic orbit and to the
magnetic-breakdown orbit .Comment: 6 pages, 4 figure
Сущность криптовалют: дескриптивный и сравнительный анализ
The aim of the article is to systematize the views on the concept of cryptocurrency from the literature and among international and national organizations and regulators, to analyze its economic essence and the place in the modern monetary and financial system. The definition and the functions of cryptocurrency are discussed in the framework of descriptive and theoretical analysis. The paper systematized the existing approaches to the concept analysis of cryptocurrency; the place of cryptocurrency in modern economic theory is shown.The article concludes that cryptocurrencies are often determined through the set of basic characteristics. Cryptocurrencies are not money, though they can perform the main function of money — to be a means of payment; they can be a means of making settlements, assets, platforms for concluding smart contracts, a means for crowdfunding. They are not private money in Hayek’s interpretation. Cryptocurrencies can be described in the framework of the models of new monetarism (payment economics).Цель статьи — систематизация существующих в литературе и у международных и национальных организаций регуляторов взглядов на понятие криптовалюты, анализ ее экономической сущности и места в современной денежнофинансовой системе. В рамках дескриптивного и теоретического анализа обсуждаются определения и функции криптовалюты. Дана систематизация существующих в литературе подходов к анализу понятия криптовалюты, показано место криптовалюты в современной экономической теории. В рамках сравнительного анализа проведено сопоставление криптовалют между собой, а также с деньгами и платежными системами. В результате исследования сделаны следующие выводы: криптовалюты зачастую определяются через набор базовых характеристик, которым они удовлетворяют; не являются деньгами, при этом могут выполнять основную функцию денег — быть средством платежа; могут быть по своей сути средством осуществления расчетов, активами, платформами для заключения смарт-контрактов, средством для краудфандинга; не являются частными деньгами в трактовке Хайека; могут быть описаны в рамках моделей нового монетаризма (экономики платежей)
Relative luminosity measurement of the LHC with the ATLAS forward calorimeter
In this paper it is shown that a measurement of the relative luminosity
changes at the LHC may be obtained by analysing the currents drawn from the
high voltage power supplies of the electromagnetic section of the forward
calorimeter of the ATLAS detector. The method was verified with a reproduction
of a small section of the ATLAS forward calorimeter using proton beams of known
beam energies and variable intensities at the U-70 accelerator at IHEP in
Protvino, Russia. The experimental setup and the data taking during a test beam
run in April 2008 are described in detail. A comparison of the measured high
voltage currents with reference measurements from beam intensity monitors shows
a linear dependence on the beam intensity. The non-linearities are measured to
be less than 0.5 % combining statistical and systematic uncertainties.Comment: 16 page
- …