NUT-Charged Black Holes in Gauss-Bonnet Gravity

We investigate the existence of Taub-NUT/bolt solutions in Gauss-Bonnet gravity and obtain the general form of these solutions in $d$ dimensions. We find that for all non-extremal NUT solutions of Einstein gravity having no curvature singularity at $r=N$, there exist NUT solutions in Gauss-Bonnet gravity that contain these solutions in the limit that the Gauss-Bonnet parameter $\alpha$ goes to zero. Furthermore there are no NUT solutions in Gauss-Bonnet gravity that yield non-extremal NUT solutions to Einstein gravity having a curvature singularity at $r=N$ in the limit $$. Indeed, we have non-extreme NUT solutions in $2+2k$ dimensions with non-trivial fibration only when the $2k$-dimensional base space is chosen to be $\mathbb{CP}^{2k}$. We also find that the Gauss-Bonnet gravity has extremal NUT solutions whenever the base space is a product of 2-torii with at most a 2-dimensional factor space of positive curvature. Indeed, when the base space has at most one positively curved two dimensional space as one of its factor spaces, then Gauss-Bonnet gravity admits extreme NUT solutions, even though there a curvature singularity exists at $r=N$. We also find that one can have bolt solutions in Gauss-Bonnet gravity with any base space with factor spaces of zero or positive constant curvature. The only case for which one does not have bolt solutions is in the absence of a cosmological term with zero curvature base space.Comment: 20 pages, referrence added, a few typos correcte

Localizing gravity on exotic thick 3-branes

We consider localization of gravity on thick branes with a non trivial structure. Double walls that generalize the thick Randall-Sundrum solution, and asymmetric walls that arise from a Z_2-symmetric scalar potential, are considered. We present a new asymmetric solution: a thick brane interpolating between two AdS_5 spacetimes with different cosmological constants, which can be derived from a ``fake supergravity'' superpotential, and show that it is possible to confine gravity on such branes.Comment: Final version, minor changes, references adde

An integrated care pathway for menorrhagia across the primary–secondary interface : patients' experience, clinical outcomes, and service utilisation

Background: ‘‘Referral’’ characterises a significant area of interaction between primary and secondary care. Despite advantages, it can be inflexible, and may lead to duplication. Objective: To examine the outcomes of an integrated model that lends weight to general practitioner (GP)-led evidence based care. Design: A prospective, non-random comparison of two services: women attending the new (Bridges) pathway compared with those attending a consultant-led one-stop menstrual clinic (OSMC). Patients’ views were examined using patient career diaries, health and clinical outcomes, and resource utilisation. Follow-up was for 8 months. Setting: A large teaching hospital and general practices within one primary care trust (PCT). Results: Between March 2002 and June 2004, 99 women in the Bridges pathway were compared with 94 women referred to the OSMC by GPs from non-participating PCTs. The patient career diary demonstrated a significant improvement in the Bridges group for patient information, fitting in at the point of arrangements made for the patient to attend hospital (ease of access) (p,0.001), choice of doctor (p = 0.020), waiting time for an appointment (p,0.001), and less ‘‘limbo’’ (patient experience of non-coordination between primary and secondary care) (p,0.001). At 8 months there were no significant differences between the two groups in surgical and medical treatment rates or in the use of GP clinic appointments. Significantly fewer (traditional) hospital outpatient appointments were made in the Bridges group than in the OSMC group (p,0.001). Conclusion: A general practice-led model of integrated care can significantly reduce outpatient attendance while improving patient experience, and maintaining the quality of care

Taub-NUT/Bolt Black Holes in Gauss-Bonnet-Maxwell Gravity

We present a class of higher dimensional solutions to Gauss-Bonnet-Maxwell equations in $2k+2$ dimensions with a U(1) fibration over a $2k$-dimensional base space $\mathcal{B}$. These solutions depend on two extra parameters, other than the mass and the NUT charge, which are the electric charge $q$ and the electric potential at infinity $V$. We find that the form of metric is sensitive to geometry of the base space, while the form of electromagnetic field is independent of $\mathcal{B}$. We investigate the existence of Taub-NUT/bolt solutions and find that in addition to the two conditions of uncharged NUT solutions, there exist two other conditions. These two extra conditions come from the regularity of vector potential at $r=N$ and the fact that the horizon at $r=N$ should be the outer horizon of the black hole. We find that for all non-extremal NUT solutions of Einstein gravity having no curvature singularity at $r=N$, there exist NUT solutions in Gauss-Bonnet-Maxwell gravity. Indeed, we have non-extreme NUT solutions in $2+2k$ dimensions only when the $2k$-dimensional base space is chosen to be $\mathbb{CP}^{2k}$. We also find that the Gauss-Bonnet-Maxwell gravity has extremal NUT solutions whenever the base space is a product of 2-torii with at most a 2-dimensional factor space of positive curvature, even though there a curvature singularity exists at $r=N$. We also find that one can have bolt solutions in Gauss-Bonnet-Maxwell gravity with any base space. The only case for which one does not have black hole solutions is in the absence of a cosmological term with zero curvature base space.Comment: 23 pages, 3 figures, typos fixed, a few references adde

Role of neuropeptides, hormones, and growth factors in regulating thymopoiesis in middle to old age

The deterioration in adaptive immunity and T-lymphocyte output and the narrowing of the T cell receptor repertoire with age are largely attributable to thymic involution. The loss of thymic function with age may be due to diminished numbers of early thymic progenitors and epithelial cells, and the loss of critical tropic factors within the thymic microenvironment. Here we review some of the recent literature demonstrating a role for neuropeptides, hormones, and growth factors that can influence thymopoiesis associated with stress and aging

qPrimerDepot: a primer database for quantitative real time PCR

Gene expression studies employing high throughput real time PCR methods require finding uniform conditions for optimal amplification of multiple targets, often a daunting task. We developed a primer database, qPrimerDepot, which provides optimized primers for all human and mouse RefSeq genes. These primers are designed to amplify desired templates under unified annealing temperature. For most intron-bearing genes, primers flank one of the largest introns thus minimizing background noise due to genomic DNA contamination. The qPrimerDepot database can be accessed at and

Relativistic Acoustic Geometry

Sound wave propagation in a relativistic perfect fluid with a non-homogeneous isentropic flow is studied in terms of acoustic geometry. The sound wave equation turns out to be equivalent to the equation of motion for a massless scalar field propagating in a curved space-time geometry. The geometry is described by the acoustic metric tensor that depends locally on the equation of state and the four-velocity of the fluid. For a relativistic supersonic flow in curved space-time the ergosphere and acoustic horizon may be defined in a way analogous the non-relativistic case. A general-relativistic expression for the acoustic analog of surface gravity has been found.Comment: 14 pages, LaTe

Applying the National Health Educator Competencies Update Project Model to Health Education

A brief overview of the six-year National Health Educator Competencies Update Project (CUP) research is provided as an introduction to a discussion of applications of the resulting CUP Hierarchical Model. Considerations for application of the model to the professional preparation, credentialing and professional development of health educators are explored. In addition, examples of the applicability of the CUP Hierarchical Model to three different work settings are presented at the Entry, Advanced 1, and Advanced 2 levels of professional practice. The benefits of being guided by a validated practice model are discussed with implications for future research endeavors

Colliding axisymmetric pp-waves

An exact solution is found describing the collision of axisymmetric pp-waves with M=0. They are impulsive in character and their coordinate singularities become point curvature singularities at the boundaries of the interaction region. The solution is conformally flat. Concrete examples are given, involving an ultrarelativistic black hole against a burst of pure radiation or two colliding beam- like waves.Comment: 6 pages, REVTeX, some misprints are correcte