5,388 research outputs found

    Computer program analyzes Buckling Of Shells Of Revolution with various wall construction, BOSOR

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    Computer program performs stability analyses for a wide class of shells without unduly restrictive approximations. The program uses numerical integration, finite difference of finite element techniques to solve with reasonable accuracy almost any buckling problem for shells exhibiting orthotropic behavior

    Buckling of shells of revolution with various wall constructions. Volume 2 - Basic equations and method of solution

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    Basic equations and method of solution for computerized analysis of shells of revolution with axisymmetric collapse and nonsymmetric bifurcation buckling behavio

    Buckling of shells of revolution with various wall constructions. Volume 3 - User's manual for BOSOR

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    Computer program for analysis of shells of revolution with axisymmetric loadin

    Buckling of shells of revolution with various wall constructions. Volume 1 - Numerical results

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    Numerical results of buckling of shells of revolution for computer progra

    Vaginal Mucormycosis: A Case Report

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    Although Zygomycetes cause life-threatening, opportunistic infections in immunocompromised hosts, the first case of vaginitis caused by Mucor species in a healthy woman is reported. Mucor vaginitis, which caused mild symptoms only, was refractory to conventional azole therapy and resistant to flucytosine. Cure was achieved with topical amphotericin B

    Trichomoniasis as Seen in a Chronic Vaginitis Clinic

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    Objective: We sought to determine the clinical and laboratory features of trichomonas vaginitis (TV) in a chronic vaginitis clinic

    Fast Genome-Wide QTL Association Mapping on Pedigree and Population Data

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    Since most analysis software for genome-wide association studies (GWAS) currently exploit only unrelated individuals, there is a need for efficient applications that can handle general pedigree data or mixtures of both population and pedigree data. Even data sets thought to consist of only unrelated individuals may include cryptic relationships that can lead to false positives if not discovered and controlled for. In addition, family designs possess compelling advantages. They are better equipped to detect rare variants, control for population stratification, and facilitate the study of parent-of-origin effects. Pedigrees selected for extreme trait values often segregate a single gene with strong effect. Finally, many pedigrees are available as an important legacy from the era of linkage analysis. Unfortunately, pedigree likelihoods are notoriously hard to compute. In this paper we re-examine the computational bottlenecks and implement ultra-fast pedigree-based GWAS analysis. Kinship coefficients can either be based on explicitly provided pedigrees or automatically estimated from dense markers. Our strategy (a) works for random sample data, pedigree data, or a mix of both; (b) entails no loss of power; (c) allows for any number of covariate adjustments, including correction for population stratification; (d) allows for testing SNPs under additive, dominant, and recessive models; and (e) accommodates both univariate and multivariate quantitative traits. On a typical personal computer (6 CPU cores at 2.67 GHz), analyzing a univariate HDL (high-density lipoprotein) trait from the San Antonio Family Heart Study (935,392 SNPs on 1357 individuals in 124 pedigrees) takes less than 2 minutes and 1.5 GB of memory. Complete multivariate QTL analysis of the three time-points of the longitudinal HDL multivariate trait takes less than 5 minutes and 1.5 GB of memory
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