Feasibility study of an Integrated Program for Aerospace vehicle Design (IPAD). Volume 3: Support of the design process

The user requirements for computer support of the IPAD design process are identified. The user-system interface, language, equipment, and computational requirements are considered

Analytical solutions of the Schr\"{o}dinger equation with the Woods-Saxon potential for arbitrary ll state

In this work, the analytical solution of the radial Schr\"{o}dinger equation for the Woods-Saxon potential is presented. In our calculations, we have applied the Nikiforov-Uvarov method by using the Pekeris approximation to the centrifugal potential for arbitrary $l$ states. The bound state energy eigenvalues and corresponding eigenfunctions are obtained for various values of $n$ and $l$ quantum numbers.Comment: 14 page

Mortality study of 18 000 patients treated with omeprazole.

Background: The long term safety of potent gastric acid suppressive therapy has yet to be established. Method: General practice record review at a median interval of 26 months followed by retrieval of details of all deaths within four years using the UK National Health Service Central Registers in 17 936 patients prescribed omeprazole in 1993–1995. Death rates were compared with general population rates. Results: Records of 17 489 patients (97.5%) were examined. A total of 12 703 patients received further scripts for antisecretory drugs, 8097 for omeprazole only (65.6%): 3097 patients have died. All cause mortality was higher in the first year (observed/expected (O/E) 1.44 (95% confidence intervals (CI) 1.34–1.55); p<0.0001) but had fallen to population expectation by the fourth year. There were significant mortality increases in the first year, falling to or below population expectation by the fourth year, for deaths ascribed to neoplasms (1.82 (95% CI 1.58–2.08); p<0.0001), circulatory diseases (1.27 (95% CI 1.13–1.43); p<0.0001), and respiratory diseases (1.37 (95% CI 1.12–1.64); p<0.001). Increased mortality ascribed to digestive diseases (2.56 (95% CI 1.87–3.43); p<0.0001) persisted, although reduced. Increased mortality rates for cancers of the stomach (4.06 (95% CI 2.60–6.04); p<0.0001), colon and rectum (1.40 (95% CI 0.84–2.18); p=0.075), and trachea, bronchus, and lung (1.64 (95% CI 1.19–2.19); p<0.01) seen in the first year had disappeared by the fourth year but that for cancer of the oesophagus had not (O/E 7.35 (95% CI 5.20–10.09) (p<0.0001) in year 1; 2.88 (95% CI 1.62–4.79) (p<0.001) in year 4). Forty of 78 patients dying of oesophageal cancer had the disease present at registration. Twenty seven of those remaining cases had clinical evidence of Barrett’s disease, stricture, ulcer, or oesophagitis at registration (O/E 3.30 (95% CI 2.17–4.80)). Six deaths occurred in patients with hiatal hernia or reflux only (O/E 1.02 (95% CI 0.37–2.22)) and five in patients without oesophageal disease (O/E 0.77 (95% CI 0.25–1.80)). No relationships were detected with numbers of omeprazole scripts received. Conclusions: Increases in mortality associated with treatment are due to pre- existing illness, including pre-existing severe oesophageal disease. There was no evidence of an increased risk of oesophageal adenocarcinoma in those without oesophageal mucosal damage recorded at registration

Asymptotic behavior of the least common multiple of consecutive arithmetic progression terms

Let $l$ and $m$ be two integers with $l>m\ge 0$, and let $a$ and $b$ be integers with $a\ge 1$ and $a+b\ge 1$. In this paper, we prove that $\log {\rm lcm}_{mn<i\le ln}\{ai+b\} =An+o(n)$, where $A$ is a constant depending on $l, m$ and $a$.Comment: 8 pages. To appear in Archiv der Mathemati

Helical, Angular and Radial Ordering in Narrow Capillaries

To enlighten the nature of the order-disorder and order-order transitions in block copolymer melts confined in narrow capillaries we analyze peculiarities of the conventional Landau weak crystallization theory of systems confined to cylindrical geometry. This phenomenological approach provides a quantitative classification of the cylindrical ordered morphologies by expansion of the order parameter spatial distribution into the eigenfunctions of the Laplace operator. The symmetry of the resulting ordered morphologies is shown to strongly depend both on the boundary conditions (wall preference) and the ratio of the cylinder radius and the wave length of the critical order parameter fluctuations, which determine the bulk ordering of the system under consideration. In particular, occurrence of the helical morphologies is a rather general consequence of the imposed cylindrical symmetry for narrow enough capillaries. We discuss also the ODT and OOT involving some other simplest morphologies. The presented results are relevant also to other ordering systems as charge-density waves appearing under addition of an ionic solute to a solvent in its critical region, weakly charged polyelectrolyte solutions in poor solvent, microemulsions etc.Comment: 6 pages, 3 figure

Mass as a Relativistic Quantum Observable

A field state containing photons propagating in different directions has a non vanishing mass which is a quantum observable. We interpret the shift of this mass under transformations to accelerated frames as defining space-time observables canonically conjugated to energy-momentum observables. Shifts of quantum observables differ from the predictions of classical relativity theory in the presence of a non vanishing spin. In particular, quantum redshift of energy-momentum is affected by spin. Shifts of position and energy-momentum observables however obey simple universal rules derived from invariance of canonical commutators.Comment: 5 pages, revised versio

Closed form representation for a projection onto infinitely dimensional subspace spanned by Coulomb bound states

The closed form integral representation for the projection onto the subspace spanned by bound states of the two-body Coulomb Hamiltonian is obtained. The projection operator onto the $n^2$ dimensional subspace corresponding to the $n$-th eigenvalue in the Coulomb discrete spectrum is also represented as the combination of Laguerre polynomials of $n$-th and $(n-1)$-th order. The latter allows us to derive an analog of the Christoffel-Darboux summation formula for the Laguerre polynomials. The representations obtained are believed to be helpful in solving the breakup problem in a system of three charged particles where the correct treatment of infinitely many bound states in two body subsystems is one of the most difficult technical problems.Comment: 7 page

Dynamic properties of the spin-1/2 XY chain with three-site interactions

We consider a spin-1/2 XY chain in a transverse (z) field with multi-site interactions. The additional terms introduced into the Hamiltonian involve products of spin components related to three adjacent sites. A Jordan-Wigner transformation leads to a simple bilinear Fermi form for the resulting Hamiltonian and hence the spin model admits a rigorous analysis. We point out the close relationships between several variants of the model which were discussed separately in previous studies. The ground-state phases (ferromagnet and two kinds of spin liquid) of the model are reflected in the dynamic structure factors of the spin chains, which are the main focus in this study. First we consider the zz dynamic structure factor reporting for this quantity a closed-form expression and analyzing the properties of the two-fermion (particle-hole) excitation continuum which governs the dynamics of transverse spin component fluctuations and of some other local operator fluctuations. Then we examine the xx dynamic structure factor which is governed by many-fermion excitations, reporting both analytical and numerical results. We discuss some easily recognized features of the dynamic structure factors which are signatures for the presence of the three-site interactions.Comment: 28 pages, 10 fugure

Microbiological influences on fracture surfaces of intact mudstone and the implications for geological disposal of radioactive waste

The significance of the potential impacts of microbial activity on the transport properties of host rocks for geological repositories is an area of active research. Most recent work has focused on granitic environments. This paper describes pilot studies investigating changes in transport properties that are produced by microbial activity in sedimentary rock environments in northern Japan. For the first time, these short experiments (39 days maximum) have shown that the denitrifying bacteria, Pseudomonas denitrificans, can survive and thrive when injected into flow-through column experiments containing fractured diatomaceous mudstone and synthetic groundwater under pressurized conditions. Although there were few significant changes in the fluid chemistry, changes in the permeability of the biotic column, which can be explained by the observed biofilm formation, were quantitatively monitored. These same methodologies could also be adapted to obtain information from cores originating from a variety of geological environments including oil reservoirs, aquifers and toxic waste disposal sites to provide an understanding of the impact of microbial activity on the transport of a range of solutes, such as groundwater contaminants and gases (e.g. injected carbon dioxide)

The least common multiple of a sequence of products of linear polynomials

Let $f(x)$ be the product of several linear polynomials with integer coefficients. In this paper, we obtain the estimate: $\log {\rm lcm}(f(1), ..., f(n))\sim An$ as $n\rightarrow\infty$, where $A$ is a constant depending on $f$.Comment: To appear in Acta Mathematica Hungaric