Progress in the Verification and Validation Efforts for START: A Spent Fuel Routing Tool

The US Department of Energys Office of Nuclear Energy is planning for an integrated waste management approach to transport, store, and eventually dispose of spent nuclear fuel and other high-level radioactive waste as part of the Integrated Waste Management program. In support of this effort, the Stakeholder Tool for Assessing Radioactive Transportation is being developed within the IWM program. This is a web-based decision support tool that can be used to analyze geospatial data related to the transportation of SNF and HLW.Comment: Presented at the '2023 ANS Winter Conference and Expo

Coherent state triplets and their inner products

It is shown that if H is a Hilbert space for a representation of a group G, then there are triplets of spaces F_H, H, F^H, in which F^H is a space of coherent state or vector coherent state wave functions and F_H is its dual relative to a conveniently defined measure. It is shown also that there is a sequence of maps F_H -> H -> F^H which facilitates the construction of the corresponding inner products. After completion if necessary, the F_H, H, and F^H, become isomorphic Hilbert spaces. It is shown that the inner product for H is often easier to evaluate in F_H than F^H. Thus, we obtain integral expressions for the inner products of coherent state and vector coherent state representations. These expressions are equivalent to the algebraic expressions of K-matrix theory, but they are frequently more efficient to apply. The construction is illustrated by many examples.Comment: 33 pages, RevTex (Latex2.09) This paper is withdrawn because it contained errors that are being correcte

Diversity of regulatory T cells in various immuno-physiological conditions

Background: Regulatory T cells (Tregs) play an active role in abrogating immune responses during microbial infections and are thus essential to maintain immune homeostasis and self-tolerance. Aberrant expression of Tregs can lead to spectrum of manifestations from allergy, chronic infections to immunopathological conditions such as autoimmunity and cancer. It is critical to have a clear understanding about the Tregs biology before attempting any possible interventions in humans. This study was undertaken to analyze the differential expression of Tregs in various physiological conditions.Methods: Peripheral blood mononuclear cells (PBMCs) were extracted from normal human subjects (n=30), pregnant females (n=10), cord blood (n=10) and patients with various immunopathological conditions such as cancer (newly diagnosed non-Hodgkin’s lymphoma, n=10), autoimmune conditions such as (type 1 diabetes mellitus-T1DM, Hashimoto’s disorder, and other autoimmune disorders, n=10 each) and in donor grafts (n=10) following allogeneic hematopoietic stem cell transplant. Flow cytometry was performed to detect CD4+CD25+FOXP3+Tregs and CD4+CD25+CD127dim/-Tregs.Results: The levels of Tregs was found to be were significantly higher in cord blood from newborn infants, patients with T1DM and Hashimoto’s disorder. In addition, the difference in Tregs level in pregnant females, patients with stem cell transplants, non-Hodgkin’s lymphoma and other autoimmune disorders were not significant.Conclusions: Till date, no comparative study was available about the status of Tregs population in normal and different physiological conditions from India. This is the first preliminary quantitative analysis of association of Tregs with different disorders. A clear cognizance of Tregs biology among various physiological conditions will be vital for targeting of these cells for any possible therapeutic modalities

Synthesis of Benzofuran Derivatives and their Evaluation of Antimicrobial Activity

2-Acetyl benzofuran (1) was synthesized by refluxing salicylaldehyde and dry chloroacetone in presence of potassium carbonate. The product formed was reacted with 2-aminobenzothiazole with catalyst p-toluene sulphonic acid to form N-[(1Z)-1-(benzofuran-2-yl)ethylidene]1,3-benzothiazol-2-amine (2). In cold condition, Staudinger reaction was carried out for compound (2) with various acid chlorides in presence of triethylamine to synthesize 4-[1-benzofuran-2-yl]-1-[1, 3-benzothiazol-2-yl]-4-methylazetidin-2-one (3a-3j). All the synthesized compounds were characterized on the basis of analytical data. The compounds were screened for their antimicrobial activities. Compound 3b,3cand 3d exhibited moderate activity

Adding and multiplying random matrices: a generalization of Voiculescu's formulae

In this paper, we give an elementary proof of the additivity of the functional inverses of the resolvents of large $N$ random matrices, using recently developed matrix model techniques. This proof also gives a very natural generalization of these formulae to the case of measures with an external field. A similar approach yields a relation of the same type for multiplication of random matrices.Comment: 11 pages, harvmac. revised x 2: refs and minor comments adde

Vector coherent state representations, induced representations, and geometric quantization: I. Scalar coherent state representations

Coherent state theory is shown to reproduce three categories of representations of the spectrum generating algebra for an algebraic model: (i) classical realizations which are the starting point for geometric quantization; (ii) induced unitary representations corresponding to prequantization; and (iii) irreducible unitary representations obtained in geometric quantization by choice of a polarization. These representations establish an intimate relation between coherent state theory and geometric quantization in the context of induced representations.Comment: 29 pages, part 1 of two papers, published versio

Dynamic Query Forms for Non-Relational Database

With quick advancement of investigative databases and web data databases are turning out to be exceptionally colossal in size and complex in nature. These databases hold extensive and heterogeneous information, with huge number of relations and qualities. So it is exceptionally hard to outline an arrangement of static inquiry structures to answer different specially appointed database inquirieson these cutting edge databases. Along these lines there is need of such framework which create Query Forms powerfully as indicated by the clients need at run time. The proposed framework Dynamic Query Form i.e.DQF framework going to give an answer by the inquiry interface in extensive and complex databases. In proposed framework, the center idea is to catch client intrigues all through client associations and to adjust the inquiry sort iteratively. Each cycle comprises of 2 sorts of client collaborations: Query Form Enrichment and Query Execution. In Query Form Enrichment DQF would prescribe a positioned rundown of question structure part to client so he/she can choose sought structure segments into current inquiry structure. In Query Execution client fills current inquiry shape and submit question, DQF going to show result and take input from client on gave question results. A client would have office to fill the inquiry frame and submit questions to see the inquiry result at every cycle. So that a question structure could be progressively refined till the client fulfills with the inquiry results

Radio masers on WX UMa : hints of a Neptune-sized planet, or magnetospheric reconnection?

RDK acknowledges funding received from the Irish Research Council (IRC) through the Government of Ireland Postgraduate Scholarship Programme. RDK and AAV acknowledges funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 817540, ASTROFLOW). We acknowledge the provisions of the Space Weather Modelling Framework (SWMF) code from the Center for Space Environment Modeling (CSEM) at the University of Michigan, and the computational resources of the Irish Centre for High End Computing (ICHEC), both of which were utilised in this work.The nearby M dwarf WX UMa has recently been detected at radio wavelengths with LOFAR. The combination of its observed brightness temperature and circular polarisation fraction suggests that the emission is generated via the electron-cyclotron maser instability. Two distinct mechanisms have been proposed to power such emission from low-mass stars: either a sub-Alfvénic interaction between the stellar magnetic field and an orbiting planet, or reconnection at the edge of the stellar magnetosphere. In this paper, we investigate the feasibility of both mechanisms, utilising the information about the star’s surrounding plasma environment obtained from modelling its stellar wind. Using this information, we show that a Neptune-sized exoplanet with a magnetic field strength of 10 – 100 G orbiting at ∼0.034 au can accurately reproduce the observed radio emission from the star, with corresponding orbital periods of 7.4 days. Due to the stellar inclination, a planet in an equatorial orbit is unlikely to transit the star. While such a planet could induce radial velocity semi-amplitudes from 7 to 396 m s−1, it is unlikely that this signal could be detected with current techniques due to the activity of the host star. The application of our planet-induced radio emission model here illustrates its exciting potential as a new tool for identifying planet-hosting candidates from long-term radio monitoring. We also develop a model to investigate the reconnection-powered emission scenario. While this approach produces less favourable results than the planet-induced scenario, it nevertheless serves as a potential alternative emission mechanism which is worth exploring further.PostprintPeer reviewe

Induction of systemic resistance in banana (Musa spp.) against Banana bunchy top virus (BBTV) by combining chitin with root-colonizing Pseudomonas fluorescens strain CHA0

Pseudomonas fluorescens strains CHA0 and Pf1 were investigated for their biocontrol efficacy against Banana bunchy top virus (BBTV) in banana (Musa spp.) alone and in combination with chitin under glasshouse and field conditions. Bioformulation of P. fluorescens strain CHA0 with chitin was effective in reducing the banana bunchy top disease (BBTD) incidence in banana under glasshouse and field conditions. In addition to disease control, the bioformulation increased the economic yield significantly compared to the untreated control. Increased accumulation of oxidative enzymes, peroxidase (PO), polyphenol oxidase (PPO), phenylalanine ammonia lyase (PAL), pathogenesis-related (PR) proteins, chitinase, beta-1,3-glucanase and phenolics were observed in CHA0 bioformulation amended with chitin-treated plants challenged with BBTV under glasshouse conditions. Indirect ELISA indicated the reduction in viral antigen concentration in P. fluorescens strain CHA0 with chitin-treated banana plants corresponding to reduced disease ratings. The present study revealed that induction of defence enzymes by P. fluorescens with chitin amendment reduced the BBTD incidence and increased bunch yield in banana