135 research outputs found
Understanding the formation of deep eutectic solvents: betaine as a universal hydrogen bond acceptor
© 2020 Wiley-VCH GmbH The mechanism of formation of betaine-based deep eutectic solvents (DES) is presented for the first time. Due to its polarity unbalance, it was found that betaine displays strong negative deviations from ideality when mixed with a variety of different organic substances. These results pave the way for a comprehensive design of novel deep eutectic solvents. A connection to biologically relevant systems was made using betaine (osmolyte) and urea (protein denaturant), showing that these two compounds formed a DES, the molecular interactions of which were greatly enhanced in the presence of water.This work was developed within the scope of the projects
CICECO-Aveiro Institute of Materials, UIDB/50011/2020 &
UIDP/50011/2020, financed by national funds through the
Portuguese Foundation for Science and Technology/MCTES, and
CIMO-Mountain Research Center, UIDB/00690/2020, financed
by national funds through the FCT/MEC and when appropriate cofinanced
by FEDER under the PT2020 Partnership Agreement.info:eu-repo/semantics/publishedVersio
Estimativa do custo de produção de leite na região bragantina.
bitstream/item/61969/1/Belem-Doc2.pd
Human induced pluripotent stem cell-derived endothelial cells in thrombosis-on-a-chip devices
A microfluidic thrombosis-on-a-chip platform was developed to compare the pro-thrombotic response of healthy and inflamed monolayers of human umbilical vein endothelial cells (HUVECs) and human induced pluripotent stem cell-derived endothelial cells (hiPSC-ECs). Inflammation was induced by exposing the endothelial cells (ECs) to an inflammatory cytokine Tumor Necrosis Factor-α (TNF-α). After human whole blood perfusion at an arterial shear rate, the platelet coverage and average clot size were determined. Healthy endothelium showed a lower platelet coverage than inflamed endothelium. A minor difference was measured for both platelet coverage and average clot sizes on inflamed HUVECs versus hiPSC-ECs
Compartimentalização e redistribuição de zinco em plantas de milho sob dois níveis de adubação em Latossolo no Cerrado.
Solos e avaliação do potencial agrossilvipastoril das microrregiões Paracatu e Unaí - Minas Gerais.
Feeding habits of six anuran (Amphibia: Anura) species in a rainforest fragment in Northeastern Brazil
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